The role of oxidative stress and NF-κB activation in late diabetic complications

BioFactors ◽  
1999 ◽  
Vol 10 (2-3) ◽  
pp. 157-167 ◽  
Author(s):  
Abdel Khalek Mohamed ◽  
Angelika Bierhaus ◽  
Stephan Schiekofer ◽  
Hans Tritschler ◽  
Reinhard Ziegler ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications

scholarly journals Efficacy of Composite Extract from Leaves and Fruits of Medicinal Plants Used in Traditional Diabetic Therapy against Oxidative Stress in Alloxan-Induced Diabetic Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Brahm Kumar Tiwari ◽  
Dileep Kumar ◽  
A. B. Abidi ◽  
Syed Ibrahim Rizvi
Keyword(s):  
Oxidative Stress ◽  
Body Weight ◽  
Diabetic Complications ◽  
Small Dose ◽  
Diabetic Rats ◽  
Vital Role ◽  
Special Focus ◽  
Wistar Strain ◽  
Glucose Plasma

Oxidative stress plays a vital role in diabetic complications. To suppress the oxidative stress mediated damage in diabetic pathophysiology, a special focus has been given on composite extract (CE) and making small dose of naturally occurring antidiabetic plants leaf and fruits. The aim of the present study was to evaluate the beneficial role of CE against alloxan- (ALX-) induced diabetes of Wistar strain rats. A dose-dependent study for CE (25, 50, and 100 mg/kg body weight) was carried out to find the effective dose of the composite compound in ALX-induced diabetic rats. ALX exposure elevated the blood glucose, plasma advanced oxidation product (AOPP), sialic acid demonstrating disturbed antioxidant status.CE at a dose of 100 mg/kg body weight restored/minimised these alterations towards normal values. In conclusion, small dose of CE possesses the capability of ameliorating the oxidative stress in ALX-induced diabetes and thus could be a promising approach in lessening diabetic complications.

The role of oxidative stress in neuropathy and other diabetic complications

1995 ◽  
Vol 11 (3) ◽  
pp. 181-192 ◽  
Author(s):  
P. Sytze Van Dam ◽  
Willem-Hendrik Gispen ◽  
Bert Bravenboer ◽  
B. Sweder Van Asbeck ◽  
D. Willem Erkelens ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications

Diabetic complications and oxidative stress: The role of phenolic‐rich extracts of saw palmetto and date palm seeds

2020 ◽  
Vol 44 (11) ◽  
Author(s):  
Amal Z. Barakat ◽  
Roqaya I. Bassuiny ◽  
Azza M. Abdel‐Aty ◽  
Saleh A. Mohamed
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications ◽  
Date Palm ◽  
Saw Palmetto ◽  
And Oxidative Stress

The Role of Oxidative Stress in Diabetic Complications

2005 ◽  
Vol 43 (2) ◽  
pp. 289-330 ◽  
Author(s):  
Dana M. Niedowicz ◽  
David L. Daleke
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications
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