scholarly journals Oxidative Stress and Diabetic Complications: The Role of Antioxidant Vitamins and Flavonoids

10.5772/57282 ◽  
2014 ◽  
Author(s):  
Omolola R. ◽  
Nicole L. ◽  
Oluwafemi O.
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications ◽  
Antioxidant Vitamins

Urate Synthesis and Oxidative Stress in Phenytoin Hepatotoxicity: The Role of Antioxidant Vitamins

2014 ◽  
Vol 17 (11) ◽  
pp. 1179-1184 ◽  
Author(s):  
Itemobong S. Ekaidem ◽  
Itoro F. Usoh ◽  
Monday I. Akpanabiat ◽  
Friday E. Uboh ◽  
Henry D. Akpan
Keyword(s):  
Oxidative Stress ◽  
Antioxidant Vitamins ◽  
And Oxidative Stress

scholarly journals Efficacy of Composite Extract from Leaves and Fruits of Medicinal Plants Used in Traditional Diabetic Therapy against Oxidative Stress in Alloxan-Induced Diabetic Rats

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Brahm Kumar Tiwari ◽  
Dileep Kumar ◽  
A. B. Abidi ◽  
Syed Ibrahim Rizvi
Keyword(s):  
Oxidative Stress ◽  
Body Weight ◽  
Diabetic Complications ◽  
Small Dose ◽  
Diabetic Rats ◽  
Vital Role ◽  
Special Focus ◽  
Wistar Strain ◽  
Glucose Plasma

Oxidative stress plays a vital role in diabetic complications. To suppress the oxidative stress mediated damage in diabetic pathophysiology, a special focus has been given on composite extract (CE) and making small dose of naturally occurring antidiabetic plants leaf and fruits. The aim of the present study was to evaluate the beneficial role of CE against alloxan- (ALX-) induced diabetes of Wistar strain rats. A dose-dependent study for CE (25, 50, and 100 mg/kg body weight) was carried out to find the effective dose of the composite compound in ALX-induced diabetic rats. ALX exposure elevated the blood glucose, plasma advanced oxidation product (AOPP), sialic acid demonstrating disturbed antioxidant status.CE at a dose of 100 mg/kg body weight restored/minimised these alterations towards normal values. In conclusion, small dose of CE possesses the capability of ameliorating the oxidative stress in ALX-induced diabetes and thus could be a promising approach in lessening diabetic complications.

The role of oxidative stress in neuropathy and other diabetic complications

1995 ◽  
Vol 11 (3) ◽  
pp. 181-192 ◽  
Author(s):  
P. Sytze Van Dam ◽  
Willem-Hendrik Gispen ◽  
Bert Bravenboer ◽  
B. Sweder Van Asbeck ◽  
D. Willem Erkelens ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications

scholarly journals Oxidative stress and increasing antioxidant defence in type 2 diabetes

2020 ◽  
Vol 1 (3) ◽  
pp. 127-136
Author(s):  
Khaider Khamzyarovich Sharafetdinov ◽  
Oxana A. Plotnikova ◽  
Victory V. Pilipenko ◽  
Dmitry B. Nikitjuk
Keyword(s):  
Oxidative Stress ◽  
Type 2 Diabetes ◽  
Antioxidant Properties ◽  
Vascular Complications ◽  
Food Products ◽  
Antioxidant Vitamins ◽  
Biologically Active ◽  
Number Of Patients

The article discusses topical issues reflecting the high prevalence of diabetes mellitus (DM), the continuing trend towards an increase in the number of patients, the high incidence of vascular complications that lead to early disability and high mortality. The review presents current data on the role of oxidative stress in the development and progression of vascular complications in patients with type 2 diabetes, as well as the mechanisms underlying the imbalance between prooxidants and the antioxidant defense system in this disease. The article presents the role of a balanced diet in achieving metabolic goals and increasing antioxidant protection in type 2 diabetes. The review provides data on the role of vitamins in the correction of metabolic disorders in type 2 diabetes. The increased need for antioxidant vitamins in diabetes is due to impaired glucose metabolism in this category of patients. Food products, which contain polyphenolic compounds, have a pronounced antioxidant and antithrombotic activity, which favorably affect metabolic parameters that contribute to weight loss. Thus, one of the ways to optimize the therapeutic nutrition of patients with type 2 diabetes is the inclusion in the standard hypocaloric diet of specialized food products containing antioxidant vitamins and minor biologically active substances with pronounced antioxidant properties.

Diabetic complications and oxidative stress: The role of phenolic‐rich extracts of saw palmetto and date palm seeds

2020 ◽  
Vol 44 (11) ◽  
Author(s):  
Amal Z. Barakat ◽  
Roqaya I. Bassuiny ◽  
Azza M. Abdel‐Aty ◽  
Saleh A. Mohamed
Keyword(s):  
Oxidative Stress ◽  
Diabetic Complications ◽  
Date Palm ◽  
Saw Palmetto ◽  
And Oxidative Stress
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