Development of a novel chemiluminescence method for the determination of cefazolin sodium in injectable powder and human urine based on a luminol-Cu(III) complex reaction in alkaline medium

Luminescence ◽  
2012 ◽  
Vol 28 (4) ◽  
pp. 592-596 ◽  
Author(s):  
Hanwen Sun ◽  
Juan Wang ◽  
Ting Wang
Keyword(s):  
Alkaline Medium ◽  
Human Urine ◽  
Complex Reaction ◽  
Chemiluminescence Method ◽  
Cefazolin Sodium

scholarly journals Determination of phenobarbital in human urine and serum usingflow injection chemiluminescence

2012 ◽  
Vol 58 (1) ◽  
pp. 88-94
Author(s):  
K. Li ◽  
L.Z. Nu ◽  
K.L. Khe ◽  
K.H. Song
Keyword(s):  
Human Urine ◽  
Pharmaceutical Preparations ◽  
Injection System ◽  
Chemiluminescence Method ◽  
Chemiluminescence Intensity ◽  
Complete Determination ◽  
Flow Injection System ◽  
Human Urine And Serum ◽  
Urine And Serum

A sensitive chemiluminescence method, based on the enhancive effect of phenobarbital on the chemiluminescence reaction between luminol and dissolved oxygen in a flow injection system, was proposed for the determination of phenobarbital. The chemiluminescence intensity responded to the concentration of phenobarbital linearly ranging from 0.05 to 10 ng⋅ml-1 with the detection limit of 0.02 ng⋅ml-1 (3σ). At a flow rate of 2.0 ml⋅min-1, a complete determination of phenobarbital, including sampling and washing, could be accomplished in 0.5 min, offering the sampling efficiency of 120 h-1 accordingly. The method was applied successfully in an assay of PB for pharmaceutical preparations, human urine and serum without any pretreatment with recovery from 95.7 to 106.7% and RSDs of less than 3.0%.

Determination of risperidone at picogram level in human urine by luminol—H2O2 chemiluminescence

2006 ◽  
Vol 60 (4) ◽  
Author(s):  
X. Xie ◽  
X. Shao ◽  
Z. Song
Keyword(s):  
Flow Injection ◽  
Human Urine ◽  
High Sensitivity ◽  
Chemiluminescence Method ◽  
Synergistic Enhancement ◽  
Relative Standard ◽  
Sensitive Determination ◽  
Flow Injection Chemiluminescence ◽  
Simple Flow

AbstractA simple flow-injection chemiluminescence method with synergistic enhancement has been investigated for the rapid and sensitive determination of antipsychotic risperidone. The synergistic action was significant in the chemiluminescence system of luminol—hydrogen peroxide with risperidone as an enhancer. The increased chemiluminescence intensity was correlated with risperidone concentration within the range from 10 pg mL−1 to 1.0 ng mL−1 with relative standard deviations lower than 5.0 % and the detection limit of 4 pg mL−1. At a flow rate of 2.0 mL min−1, the flow-injection chemiluminescence method exhibited both a high sensitivity and excellent selectivity giving a throughput of 120 times per hour. The proposed method was successfully applied to determine the risperidone content in human urine without any pretreatment. It was found that the excretive amounts of risperidone reached their maximum after taking 2.0 mg of risperidone for 1 h, with a total excretive ratio of 17.37 % in 8.5 h.

A CHEMICAL METHOD FOR THE DETERMINATION OF 2-HYDROXYOESTRONE IN HUMAN URINE

1973 ◽  
Vol 71 (4_Suppl) ◽  
pp. S110
Author(s):  
H. P. Gelbke ◽  
R. Knuppen
Keyword(s):  
Human Urine ◽  
Chemical Method
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