A Low‐Frequency Pulsed Magnetic Field Reduces Neuropathic Pain by Regulating NaV 1.8 and NaV 1.9 Sodium Channels at the Transcriptional Level in Diabetic Rats

2021 ◽  
Author(s):  
Cagil Coskun ◽  
Isil Ocal ◽  
Ismail Gunay
Keyword(s):  
Magnetic Field ◽  
Neuropathic Pain ◽  
Sodium Channels ◽  
Low Frequency ◽  
Diabetic Rats ◽  
Pulsed Magnetic Field ◽  
Transcriptional Level

scholarly journals Effect of low frequency pulsed magnetic field on gravitropic response and cell elongation in coleoptiles of maize seedlings

2016 ◽  
Vol 35 (04) ◽  
pp. 416-424
Author(s):  
Anna Kościarz-Grzesiok ◽  
Karolina Sieroń-Stołtny ◽  
Malgorzata Polak ◽  
Aleksander Sieroń ◽  
Waldemar Karcz
Keyword(s):  
Magnetic Field ◽  
Cell Elongation ◽  
Low Frequency ◽  
Pulsed Magnetic Field ◽  
Maize Seedlings ◽  
Gravitropic Response

Pulsed magnetic field enhances therapeutic efficiency of mesenchymal stem cells in chronic neuropathic pain model

2017 ◽  
Vol 38 (4) ◽  
pp. 255-264 ◽  
Author(s):  
Tufan Mert ◽  
Akif Hakan Kurt ◽  
İdiris Altun ◽  
Ahmet Celik ◽  
Furkan Baran ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Stem Cells ◽  
Mesenchymal Stem Cells ◽  
Neuropathic Pain ◽  
Pulsed Magnetic Field ◽  
Chronic Neuropathic Pain ◽  
Pain Model ◽  
Therapeutic Efficiency ◽  
Neuropathic Pain Model

Gender-Specific differences in pulsed magnetic field exposed to diabetic neuropathic rats

2019 ◽  
Author(s):  
Iþýl Öcal ◽  
M. Bertan Yýlmaz ◽  
Aykut Pelit ◽  
Fatma Çoban ◽  
Bora Taºtekin ◽  
...  
Keyword(s):  
Magnetic Field ◽  
Weight Loss ◽  
Type 1 Diabetes ◽  
Blood Glucose ◽  
Diabetic Rats ◽  
Pulsed Magnetic Field ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Mechanical Threshold

Type-1 diabetes mellitus is an insulin-dependent autoimmune disease, which is very common in the human populations regardless of gender. The aim of this study was to evaluate the effects of pulsed magnetic field (PMF), a non-invasive procedure, on male and female rats with type 1 diabetes, particularly on weight loss ratios, blood glucose levels and diabetic neuropathy. Before, the experimental groups were divided into three groups as control (C (F or M), diabetes (DM (F or M), controlled diabetes (DM(F)-INS or DM(M)-INS) groups according to their sex differences, then these experimental groups were exposed to magnetic field effect (PMF). The rats in the PMF groups were exposed to the pulsed magnetic field at 50 Hz (1.5 mT intensity) for 1h/5days/month. The body weights and blood glucose levels were measured once a week over a month. Female and male diabetic rats developing diabetic neuropathy were evaluated with thermal (thermal latency) and dynamic (mechanical threshold) plantar tests. After six-weeks of PMF treatment, the weight loss rate and increased blood glucose levels due to diabetes reversed in both female and male diabetic rats upon PMF treatment (p less than 0.05). In diabetic neuropathic female and male rats, the thermal latency values increased, while the mechanical threshold values decreased. The reduction in diabetic neuropathic rats were statistically significant in diabetic rats (p less than 0.05). The increased or decreased mechanical threshold and thermal latency values in diabetic neuropathic rats were statistically significant in only male diabetic rats (p less than 0.05). Our studies may imply that the effect of PMF in neuropathic pain is gender dependent further inferring that hormonal mechanisms were also important in PMF dependent regulation.

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