Extremely low-frequency electromagnetic field induces neural differentiation of hBM-MSCs through regulation of (Zn)-metallothionein-3

2017 ◽  
Vol 38 (5) ◽  
pp. 364-373 ◽  
Author(s):  
Anastasia Rosebud Aikins ◽  
Sung-Won Hong ◽  
Hyun-Jung Kim ◽  
Cheol-Ho Yoon ◽  
Joo-Hee Chung ◽  
...  
Keyword(s):  
Electromagnetic Field ◽  
Neural Differentiation ◽  
Low Frequency ◽  
Extremely Low Frequency

Extremely low-frequency electromagnetic field (EMF) generates alterations in the synthesis and secretion of oestradiol-17 β (E 2 ) in uterine tissues: An in vitro study

2018 ◽  
Vol 110 ◽  
pp. 86-95 ◽  
Author(s):  
Anna Koziorowska ◽  
Ewa Monika Waszkiewicz ◽  
Maria Romerowicz-Misielak ◽  
Kamila Zglejc-Waszak ◽  
Anita Franczak
Keyword(s):  
Electromagnetic Field ◽  
Low Frequency ◽  
In Vitro Study ◽  
Vitro Study ◽  
Extremely Low Frequency

scholarly journals Investigation of the Effect of Sodium Selenate on Acetylcholinesterase Activity under Extremely Low Frequency Electromagnetic Field

2012 ◽  
Vol 4 (1) ◽  
Author(s):  
Ezzatollah Fathi ◽  
Raheleh Farahzadi
Keyword(s):  
Electromagnetic Field ◽  
Structural Changes ◽  
Tertiary Structure ◽  
Low Frequency ◽  
Acetylcholinesterase Activity ◽  
The Elderly ◽  
Skin Aging ◽  
Sodium Selenate ◽  
Spectroscopic Techniques ◽  
Extremely Low Frequency

Acetylcholinestrase (AChE EC 3.1.1.7) is one of the most important enzymes in nervous system, which plays a role in Alzheimer’s disease. Selenium is a vital micronutrient and many investigations have been performed about the physiological, biochemical and behavioral effects of this element, such as postponing the Alzheimer's symptoms in the elderly and delaying the initiation signs of skin aging. Recent studies have shown that this element protects various enzymes against the toxicity caused by heavy metals such as; Pb, Al, Cu and Cd. AChE activity is altered under the influence of extremely low frequency electromagnetic field (ELF-EMF). In this study, the effects of ELF-EMF, with 0.3 mT field intensity and 50, 100, 217 Hz frequencies, were investigated on the AChE, in the presence of different concentrations of sodium selenate, using UV-Visible, fluorescence and circular dichroism spectroscopic techniques. The results demonstrated that the enzyme activity declined by increasing the frequency and the amount of sodium selenate. Also, significant structural changes occurred in the secondary and tertiary structures of AChE. Our results showed that with increasing the concentration of sodium selenate transition from α-helix to β-structure was appeared in the presence of ELF-EMF. In conclusion, according to changes observed in the secondary and tertiary structure of enzyme, it is proposed that these fields are able to affect the structure and dynamics of the active site gorge of AChE.

scholarly journals Effectiveness of Extremely Low Frequency Electromagnetic Field and Pulsed Low-Level Laser Therapy in Acute Stroke Treatment

2020 ◽  
Vol 7 (3) ◽  
pp. 127-131
Author(s):  
Farzad Ashrafi ◽  
Amir Rezaei ◽  
Arash Azhideh ◽  
Faraj Tabeie ◽  
Latif Gachkar ◽  
...  
Keyword(s):  
Electromagnetic Field ◽  
Medical Condition ◽  
Low Frequency ◽  
Cognitive Status ◽  
Low Level Laser Therapy ◽  
Stroke Treatment ◽  
Extremely Low Frequency ◽  
Level Laser ◽  
Significant Difference ◽  
Before And After

Introduction: Stroke is one of the most devastating neurologic conditions in the world. Despite all the efforts that have been made for effective treatment, the prevalence of this medical condition is still high. One of the new methods in the treatment of patients is the use of low power laser and pulsed magnetic fields. The previous studies investigated the effectiveness of these methods individually. However, the present study aimed to investigate their effectiveness in combination. Methods: We divided the patients into control (n=26) and experimental (n=26) groups. The primary variables included the Mini-Mental State Examination (MMSE) and the National Institute of Health Stroke Scale (NIHSS). The experimental group received extremely low-frequency electromagnetic field (EMF-ELF) treatment with 1 mT power and laser in rejection with a wavelength of 840 nm for 5 days and 45 min/d. Results: The variable measured during this study, in addition to comparing the results of the intervention between the control and experimental groups, showed a significant difference in all indicators before and after the intervention. The mean and standard deviations of the modified Rankin scale (mRS), functional status (Barthel’s index), and cognitive status (MMSE) (P<0.001) were signed between 2 groups. Conclusion: Laser and magnetic field combination can be effective in the treatment of stroke. Further studies are recommended to ensure a better comparison.

Extremely Low‐Frequency Electromagnetic Field Altered PPARγ and CCL2 Levels and Suppressed CD44 + / CD24 − Breast Cancer Cells Characteristics

2020 ◽  
Vol 41 (8) ◽  
pp. 812-823
Author(s):  
In‐Rok Oh ◽  
Bernardo Raymundo ◽  
Sung A Jung ◽  
Hyun Jung Kim ◽  
Jung‐Keug Park ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Electromagnetic Field ◽  
Cancer Cells ◽  
Breast Cancer Cells ◽  
Low Frequency ◽  
Extremely Low Frequency

scholarly journals Human Gingival Fibroblasts Exposed to Extremely Low-Frequency Electromagnetic Fields: In Vitro Model of Wound-Healing Improvement

2019 ◽  
Vol 20 (9) ◽  
pp. 2108 ◽  
Author(s):  
Erica Costantini ◽  
Bruna Sinjari ◽  
Chiara D’Angelo ◽  
Giovanna Murmura ◽  
Marcella Reale ◽  
...  
Keyword(s):  
Wound Healing ◽  
Electromagnetic Field ◽  
Electromagnetic Fields ◽  
Wound Repair ◽  
Healing Process ◽  
Low Frequency ◽  
Gingival Fibroblasts ◽  
Field Exposure ◽  
Extremely Low Frequency

Several clinical studies have suggested the impact of sinusoidal and pulsed electromagnetic fields in quickening wound repair processes and tissue regeneration. The clinical use of extremely low-frequency electromagnetic fields could represent a novel frontier in tissue repair and oral health, with an interesting clinical perspective. The present study aimed to evaluate the effect of an extremely low-frequency sinusoidal electromagnetic field (SEMF) and an extremely low-frequency pulsed electromagnetic field (PEMF) with flux densities of 1 mT on a model of oral healing process using gingival fibroblasts. An in vitro mechanical injury was produced to evaluate wound healing, migration, viability, metabolism, and the expression of selected cytokines and protease genes in fibroblasts exposed to or not exposed to the SEMF and the PEMF. Interleukin 6 (IL-6), transforming growth factor beta 1 (TGF-β), metalloproteinase 2 (MMP-2), monocyte chemoattractant protein 1 (MCP-1), inducible nitric oxide synthase (iNOS), and heme oxygenase 1 (HO-1) are involved in wound healing and tissue regeneration, favoring fibroblast proliferation, chemotaxis, and activation. Our results show that the exposure to each type of electromagnetic field increases the early expression of IL-6, TGF-β, and iNOS, driving a shift from an inflammatory to a proliferative phase of wound repair. Additionally, a later induction of MMP-2, MCP-1, and HO-1 was observed after electromagnetic field exposure, which quickened the wound-healing process. Moreover, electromagnetic field exposure influenced the proliferation, migration, and metabolism of human gingival fibroblasts compared to sham-exposed cells. This study suggests that exposure to SEMF and PEMF could be an interesting new non-invasive treatment option for wound healing. However, additional studies are needed to elucidate the best exposure conditions to provide the desired in vivo treatment efficacy.

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