Simplified approach for determination of hepatic drug-oxidizing capacity using trimethadione metabolism as an indicator

1989 ◽  
Vol 10 (6) ◽  
pp. 617-620 ◽  
Author(s):  
Einosuke Tanaka ◽  
Shinichi Kobayashi ◽  
Koichi Nakamura ◽  
Eiji Uchida ◽  
Hajime Yasuhara
Keyword(s):  
Hepatic Drug ◽  
Simplified Approach

Influence of Inlet Conditions on the Thermohydrodynamic State of a Fully Circumferentially Grooved Journal Bearing

2000 ◽  
Vol 123 (3) ◽  
pp. 525-532 ◽  
Author(s):  
P. S. Keogh ◽  
M. M. Khonsari
Keyword(s):  
Temperature Distribution ◽  
Energy Equation ◽  
Journal Bearing ◽  
Hydrodynamic Bearing ◽  
Simplified Approach ◽  
Supply Pressure ◽  
Axial Temperature ◽  
Viscosity Variation ◽  
Inlet Conditions

A thermohydrodynamic (THD) analysis of a fully circumferentially grooved hydrodynamic bearing is presented. The pressure distribution is obtained using the short bearing approximation taking into account the viscosity variation in the radial and circumferential coordinates. The axial temperature variation is also included by an axial averaging technique, which incorporates the supply pressure and film entry temperature in the energy equation. It is found that the determination of the lubricant temperature at the entry to the film plays an important role in the overall temperature distribution in the bearing. A simplified approach for determining this temperature is presented. An extensive set of experimental results performed by Maki and Ezzat (1980, ASME J. Lubr. Technol., 102, pp. 8–14) is used for validation purposes. The results show that mixing in the inlet groove may cause the film entry temperature to be significantly different from the nominal supply temperature and hence have a significant influence on the bearing temperature.

scholarly journals On a Simplified Model for Numerical Simulation of Wear During Dry Rolling Contacts

2008 ◽  
Vol 131 (1) ◽  
Author(s):  
L. Chevalier ◽  
A. Eddhahak-Ouni ◽  
S. Cloupet
Keyword(s):  
Contact Area ◽  
Power Distribution ◽  
Contact Problems ◽  
Rolling Contact ◽  
Normal Loading ◽  
Fast Determination ◽  
Wear Process ◽  
Simplified Approach ◽  
Rolling Contacts

We deal with rolling contact between quasi-identical bodies. As normal and tangential problems are uncoupled in that case, the simplified approach to determine contact area and normal loading distribution for rolling contact problems is presented in Sec. 2. In Sec. 3, the solution of the tangential problem is used to update the rolling profiles and enables to follow the wear evolution versus time. The method used to solve the normal problem is called semi-Hertzian approach with diffusion. It allows fast determination of the contact area for non-Hertzian cases. The method is based on the geometrical indentation of bodies in contact: The contact area is found with correct dimensions but affected by some irregularities coming from the curvature’s discontinuity that may arise during a wear process. Diffusion between independent stripes smoothes the contact area and the pressure distribution. The tangential problem is also solved on each stripe of the contact area using an extension of the simplified approach developed by Kalker and called FASTSIM. At the end, this approach gives the dissipated power distribution in the contact during rolling and this power is related to wear by Archard’s law. This enables the profiles of the bodies to be updated and the evolution of the geometry to be followed.

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