Pharmacokinetics of drugs in blood I. Unusual distribution of gentamicin

1981 ◽  
Vol 2 (1) ◽  
pp. 89-97 ◽  
Author(s):  
Myung G. Lee ◽  
Mei-Ling Chen ◽  
Shiew-Mei Huang ◽  
Win L. Chiou
Keyword(s):  
Unusual Distribution ◽  
Drugs In Blood

Pharmacokinetics of drugs in blood VII: Unusual distribution and blood storage effect of vancomycin

1992 ◽  
Vol 13 (4) ◽  
pp. 305-310 ◽  
Author(s):  
Wan G. Shin ◽  
Myung G. Lee ◽  
Min H. Lee ◽  
Nak D. Kim
Keyword(s):  
Storage Effect ◽  
Blood Storage ◽  
Unusual Distribution ◽  
Drugs In Blood

Genomic insights from Monoglobus pectinilyticus: a pectin-degrading specialist bacterium in the human colon

2020 ◽  
Author(s):  
CC Kim ◽  
GR Healey ◽  
WJ Kelly ◽  
ML Patchett ◽  
Z Jordens ◽  
...  
Keyword(s):  
Cell Surface ◽  
Degradation Products ◽  
Model Organism ◽  
Human Colon ◽  
Surface Proteins ◽  
Human Gut ◽  
Pectate Lyases ◽  
Unusual Distribution ◽  
Degrading Bacteria ◽  
Acetyl Esterases

© 2019, International Society for Microbial Ecology. Pectin is abundant in modern day diets, as it comprises the middle lamellae and one-third of the dry carbohydrate weight of fruit and vegetable cell walls. Currently there is no specialized model organism for studying pectin fermentation in the human colon, as our collective understanding is informed by versatile glycan-degrading bacteria rather than by specialist pectin degraders. Here we show that the genome of Monoglobus pectinilyticus possesses a highly specialized glycobiome for pectin degradation, unique amongst Firmicutes known to be in the human gut. Its genome encodes a simple set of metabolic pathways relevant to pectin sugar utilization, and its predicted glycobiome comprises an unusual distribution of carbohydrate-active enzymes (CAZymes) with numerous extracellular methyl/acetyl esterases and pectate lyases. We predict the M. pectinilyticus degradative process is facilitated by cell-surface S-layer homology (SLH) domain-containing proteins, which proteomics analysis shows are differentially expressed in response to pectin. Some of these abundant cell surface proteins of M. pectinilyticus share unique modular organizations rarely observed in human gut bacteria, featuring pectin-specific CAZyme domains and the cell wall-anchoring SLH motifs. We observed M. pectinilyticus degrades various pectins, RG-I, and galactan to produce polysaccharide degradation products (PDPs) which are presumably shared with other inhabitants of the human gut microbiome (HGM). This strain occupies a new ecological niche for a primary degrader specialized in foraging a habitually consumed plant glycan, thereby enriching our understanding of the diverse community profile of the HGM.

scholarly journals The Unusual Period Distribution of the RR Lyrae Variables in NGC 5897

1989 ◽  
Vol 111 ◽  
pp. 287-287
Author(s):  
Amelia Wehlau
Keyword(s):  
Light Curves ◽  
Instability Strip ◽  
Rr Lyrae Stars ◽  
Rr Lyrae ◽  
Period Distribution ◽  
Unusual Distribution ◽  
Photoelectric Observations ◽  
Lyrae Stars ◽  
Branch Star ◽  
Central Concentration

AbstractAttention is called to the rather unusual distribution of the periods of the RR Lyrae variables in NGC 5897, a metal-poor halo globular cluster with a very low central concentration. Of the seven RR Lyrae stars known in the cluster, three have periods between 0.797 and 0.856 day and two have periods of 0.45 and 0.42 day. The other two have periods of 0.34 and 0.35 day with much lower amplitudes of variation. Due to the lack of crowding in this cluster photoelectric observations and Fourier decompositions of the resulting light curves should be possible for at least six of the RR Lyrae variables. In addition, the cluster appears to contain a non-variable horizontal branch star, SK 120, lying within the instability strip. As this is the only well documented case of such a star, photoelectric observations of this star would also be desirable.

Non-optimal onsets in Chamicuro: an inventory maximised in coda position

Phonology ◽  
2001 ◽  
Vol 18 (3) ◽  
pp. 361-386 ◽  
Author(s):  
Steve Parker
Keyword(s):  
Side Effect ◽  
Final Position ◽  
Unusual Distribution ◽  
Positional Markedness

The widely attested onset/coda asymmetry involves a situation in which the inventory of phonemes in syllable-final position in a particular language is a subset of those which contrast in onsets. The inverse of this pattern has been claimed to never occur (Goldsmith 1990, Beckman 1998). However, this prediction is falsified by Chamicuro, a Peruvian language in which /h/ and /[glottal plosive]/ are systematically restricted to coda position. Since no permutation of all known constraints can account for this unusual distribution, a new constraint is necessary. I propose that we invoke HAVEPLACE and subcategorise it for onsets. This positional markedness filter permits placeless (laryngeal) consonants to surface in codas, but blocks them in onsets. A beneficial side-effect of this analysis is that it preserves the onset/coda asymmetry while allowing /[glottal plosive]/ and /h/ to be the only principled exceptions to it.

Revision ofTrassedia(Hymenoptera: Ceraphronidae), an Evolutionary Relict With an Unusual Distribution

2018 ◽  
Vol 2 (6) ◽  
Author(s):  
István Mikó ◽  
Carolyn Trietsch ◽  
Thomas van de Kamp ◽  
Lubomír Masner ◽  
Jonah M Ulmer ◽  
...  
Keyword(s):  
Unusual Distribution

Evidence for an unusual distribution of chlorphentermine in vivo

1974 ◽  
Vol 282 (2) ◽  
pp. 113-122 ◽  
Author(s):  
K. -U. Seiler ◽  
O. Wassermann
Keyword(s):  
Unusual Distribution
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