Shear stress computation in a millimeter thin flat panel photobioreactor: Numerical design validated by experiments

2020 ◽  
Author(s):  
Wenbiao Jiang ◽  
Wendie Levasseur ◽  
Joel Casalinho ◽  
Thierry Martin ◽  
François Puel ◽  
...  
Keyword(s):  
Shear Stress ◽  
Flat Panel ◽  
Numerical Design ◽  
Stress Computation

Wall shear stress computation for blood vessels and estimation by machine leaning

2017 ◽  
Vol 2017.30 (0) ◽  
pp. 254
Author(s):  
Hiroshi SUITO ◽  
Viet Q.H. HUYNH ◽  
Kenji TAKIZAWA ◽  
Takuya UEDA
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Blood Vessels ◽  
Machine Leaning ◽  
Stress Computation ◽  
Wall Shear

scholarly journals Numerical Design and Laboratory Testing of Encapsulated PCM Panels for PCM-Air Heat Exchangers

2021 ◽  
Vol 11 (2) ◽  
pp. 676
Author(s):  
Thiago Santos ◽  
Luiz C. Wrobel ◽  
Nick Hopper ◽  
Maria Kolokotroni
Keyword(s):  
Heat Transfer ◽  
Pressure Drop ◽  
Heat Exchangers ◽  
Flat Panel ◽  
Cfd Simulations ◽  
Numerical Design ◽  
Laboratory Results ◽  
The Cost ◽  
Effective Design ◽  
Transfer Pressure

Heat transfer between encapsulated PCM panels and air plays an important role in PCM-Air heat exchangers. A new design for the encapsulation panel was developed considering practical aspects such as the cost of production and ease of manufacturing, in addition to heat transfer and pressure drop. A number of encapsulated panel surfaces were first investigated via 3D CFD simulations and compared with an existing panel in use by a commercial PCM-Air heat exchanger manufacturer. After validation, 2D CFD simulations were carried out for 32 different geometries to select the most effective design, which was fabricated and tested in the laboratory. Laboratory parameters tested included heat transfer, pressure drop and melting/solidifying. The laboratory results confirmed the improvements of the new panel in comparison with the existing panel and a flat panel. It was found that the proposed design doubled the heat transfer, holds 13.7% more material and the fan can overcome the increased pressure drop.

Numerical design and optimization of hydraulic resistance and wall shear stress inside pressure-driven microfluidic networks

Lab on a Chip ◽  
2015 ◽  
Vol 15 (21) ◽  
pp. 4187-4196 ◽  
Author(s):  
Hazem Salim Damiri ◽  
Hamzeh Khalid Bardaweel
Keyword(s):  
Shear Stress ◽  
Wall Shear Stress ◽  
Hydraulic Resistance ◽  
Design And Optimization ◽  
Microfluidic Network ◽  
Numerical Design ◽  
Microfluidic Networks ◽  
Wall Shear ◽  
Pressure Driven

Control of total wall shear stress in ann-generation microfluidic network.

Effect of shear stress on the growth of continuous culture of Synechocystis PCC 6803 in a flat-panel photobioreactor

2014 ◽  
Vol 31 (7) ◽  
pp. 1233-1236 ◽  
Author(s):  
Min-Gyu Sung ◽  
Won-Sub Shin ◽  
Woong Kim ◽  
Jong-Hee Kwon ◽  
Ji-Won Yang
Keyword(s):  
Shear Stress ◽  
Continuous Culture ◽  
Synechocystis Pcc 6803 ◽  
Flat Panel ◽  
Pcc 6803

The molecular mechanism of mechanotransduction in vascular homeostasis and disease

2020 ◽  
Vol 134 (17) ◽  
pp. 2399-2418
Author(s):  
Yoshito Yamashiro ◽  
Hiromi Yanagisawa
Keyword(s):  
Shear Stress ◽  
Blood Vessels ◽  
Vessel Wall ◽  
Vascular Diseases ◽  
Cell Interactions ◽  
Aortic Aneurysms ◽  
Cyclic Stretch ◽  
Mechanical Stimuli ◽  
Vascular Homeostasis ◽  
Matrix Cell

Abstract Blood vessels are constantly exposed to mechanical stimuli such as shear stress due to flow and pulsatile stretch. The extracellular matrix maintains the structural integrity of the vessel wall and coordinates with a dynamic mechanical environment to provide cues to initiate intracellular signaling pathway(s), thereby changing cellular behaviors and functions. However, the precise role of matrix–cell interactions involved in mechanotransduction during vascular homeostasis and disease development remains to be fully determined. In this review, we introduce hemodynamics forces in blood vessels and the initial sensors of mechanical stimuli, including cell–cell junctional molecules, G-protein-coupled receptors (GPCRs), multiple ion channels, and a variety of small GTPases. We then highlight the molecular mechanotransduction events in the vessel wall triggered by laminar shear stress (LSS) and disturbed shear stress (DSS) on vascular endothelial cells (ECs), and cyclic stretch in ECs and vascular smooth muscle cells (SMCs)—both of which activate several key transcription factors. Finally, we provide a recent overview of matrix–cell interactions and mechanotransduction centered on fibronectin in ECs and thrombospondin-1 in SMCs. The results of this review suggest that abnormal mechanical cues or altered responses to mechanical stimuli in EC and SMCs serve as the molecular basis of vascular diseases such as atherosclerosis, hypertension and aortic aneurysms. Collecting evidence and advancing knowledge on the mechanotransduction in the vessel wall can lead to a new direction of therapeutic interventions for vascular diseases.

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