Effect of alcohol chain length on the enzymatic resolution of racemic mandelic acid and kinetic study

2014 ◽  
pp. n/a-n/a ◽  
Author(s):  
Yang Pan ◽  
Ke-Wen Tang ◽  
Chang-Qing He ◽  
Wei Yi ◽  
Wei Zhu ◽  
...  
Keyword(s):  
Kinetic Study ◽  
Chain Length ◽  
Mandelic Acid ◽  
Enzymatic Resolution

Kinetic Study on the Enzymatic Resolution of Homophenylalanine Ester Using Ionic Liquids

2003 ◽  
Vol 19 (3) ◽  
pp. 1016-1018 ◽  
Author(s):  
H. Zhao ◽  
R.G. Luo ◽  
S.V. Malhotra
Keyword(s):  
Ionic Liquids ◽  
Kinetic Study ◽  
Enzymatic Resolution

Kinetic Study on the Capping Reaction of Living Polyisobutylene with 1,1-Diarylethylenes. 2. Effect of Chain Length†

2000 ◽  
Vol 33 (3) ◽  
pp. 743-747 ◽  
Author(s):  
Helmut Schlaad ◽  
Younghwan Kwon ◽  
Rudolf Faust ◽  
Herbert Mayr
Keyword(s):  
Kinetic Study ◽  
Chain Length

Mechanism of Oxidative Decarboxylation of α-Hydroxy Acids by Bromine Water. Part I. Oxidation in Neutral and Alkaline Medium

1971 ◽  
Vol 49 (4) ◽  
pp. 649-653 ◽  
Author(s):  
Judith M. Pink ◽  
Ross Stewart
Keyword(s):  
Steady State ◽  
Kinetic Study ◽  
Oxidation Rate ◽  
Mandelic Acid ◽  
Oxidative Decarboxylation ◽  
Hydroxy Acids ◽  
Bromine Water ◽  
Benzilic Acid ◽  
Hydroxylic Proton ◽  
Good Agreement

A kinetic study of the oxidative decarboxylation of α-hydroxy acids by bromine water shows that above pH 6 Br2 is a much more significant oxidant for these compounds than is HOBr, and that OBr− is virtually inert. The rate law – d[oxidant]/dt = k[oxidant][substrate] is observed and the oxidation pattern differs from that of alcohols in that the α-hydrogen is not involved in the reaction.All the compounds studied (benzilic, mandelic, and 2-hydroxy-2-methylpropanoic acids) exhibit bell-shaped pH-rate profiles with maxima at about pH 8. A mechanism is proposed involving the attack of Br2 (or HOBr) at the carboxylate site concurrently with base-catalyzed loss of the hydroxylic proton. A steady state treatment based on this mechanism yields calculated rates in good agreement with the observed values. Furthermore, the same parameters predict the rates observed at lower pH in the presence of added excess bromide. The Br2 oxidation rate is greater than the HOBr rate by a factor of 60 for benzilic acid, 37 for 2-hydroxy-2-methylpropanoic acid, and 10 for mandelic acid.

Oxidation of mandelic acid by alkaline potassium permanganate. A kinetic study

1998 ◽  
Vol 11 (7) ◽  
pp. 448-454 ◽  
Author(s):  
Rafeek G. Panari ◽  
Ravindra B. Chougale ◽  
Sharanappa T. Nandibewoor
Keyword(s):  
Kinetic Study ◽  
Potassium Permanganate ◽  
Mandelic Acid
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