scholarly journals Suppression of Murine Lupus by CD 4+ and CD 8+ Treg Cells Induced by T Cell–Targeted Nanoparticles Loaded With Interleukin‐2 and Transforming Growth Factor β

2019 ◽  
Vol 71 (4) ◽  
pp. 632-640 ◽  
Author(s):  
David A. Horwitz ◽  
Sean Bickerton ◽  
Michael Koss ◽  
Tarek M. Fahmy ◽  
Antonio La Cava
Keyword(s):  
T Cell ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Interleukin 2 ◽  
Transforming Growth Factor Β ◽  
Treg Cells ◽  
Murine Lupus ◽  
Targeted Nanoparticles

scholarly journals Cell-Intrinsic Transforming Growth Factor-β Signaling Mediates Virus-Specific CD8+ T Cell Deletion and Viral Persistence In Vivo

Immunity ◽  
2009 ◽  
Vol 31 (1) ◽  
pp. 145-157 ◽  
Author(s):  
Roberto Tinoco ◽  
Victor Alcalde ◽  
Yating Yang ◽  
Karsten Sauer ◽  
Elina I. Zuniga
Keyword(s):  
T Cell ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Viral Persistence ◽  
Transforming Growth Factor Β ◽  
Cd8 T Cell ◽  
Cell Deletion

Transforming growth factor-β in T cell tolerance

2007 ◽  
pp. 3-6
Author(s):  
M. O. Li ◽  
Y. Laouar ◽  
Y. Peng ◽  
L. Gorelik ◽  
R. A. Flavell
Keyword(s):  
T Cell ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
T Cell Tolerance ◽  
Cell Tolerance

scholarly journals Latency-Associated Peptide of Transforming Growth Factor β Enhances Mycobacteriocidal Immunity in the Lung duringMycobacterium bovis BCG Infection in C57BL/6 Mice

2000 ◽  
Vol 68 (11) ◽  
pp. 6505-6508 ◽  
Author(s):  
K. A. Wilkinson ◽  
T. D. Martin ◽  
S. M. Reba ◽  
H. Aung ◽  
R. W. Redline ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
T Cell ◽  
Growth Factor ◽  
Mrna Expression ◽  
Mycobacterium Bovis ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Gamma Interferon ◽  
T Cell Proliferation

ABSTRACT Latency-associated peptide of transforming growth factor β (TGF-β) (LAP) was used to determine whether in vivo modulation of TGF-β bioactivity enhanced pulmonary immunity to Mycobacterium bovis BCG infection in C57BL/6 mice. LAP decreased BCG growth in the lung and enhanced antigen-specific T-cell proliferation and gamma interferon mRNA expression. Thus, susceptibility of the lung to primary BCG infection may be partially mediated by the immunosuppressive effects of TGF-β.

scholarly journals The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation

Immunity ◽  
2011 ◽  
Vol 34 (2) ◽  
pp. 201-212 ◽  
Author(s):  
Xing Chang ◽  
Fang Liu ◽  
Xiaofang Wang ◽  
Aiping Lin ◽  
Hongyu Zhao ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
T Cell ◽  
Growth Factor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
T Cell Differentiation ◽  
Helper T Cell

Transforming Growth Factor-β Pathway Serves as a Primary Tumor Suppressor in CD8+ T Cell Tumorigenesis

2004 ◽  
Vol 64 (18) ◽  
pp. 6524-6529 ◽  
Author(s):  
Philip J. Lucas ◽  
Nicole McNeil ◽  
Eva Hilgenfeld ◽  
Baishakhi Choudhury ◽  
Seong-Jin Kim ◽  
...  
Keyword(s):  
T Cell ◽  
Growth Factor ◽  
Tumor Suppressor ◽  
Primary Tumor ◽  
Transforming Growth Factor ◽  
Transforming Growth Factor Β ◽  
Cd8 T Cell
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