scholarly journals Prevalence and Responsiveness to Treatment of Lung Abnormalities on Chest Computed Tomography in Patients With Microscopic Polyangiitis: A Multicenter, Longitudinal, Retrospective Study of One Hundred Fifty Consecutive Hospital-Based Japanese Patients

2016 ◽  
Vol 68 (3) ◽  
pp. 713-723 ◽  
Author(s):  
Mieko Yamagata ◽  
Kei Ikeda ◽  
Kenji Tsushima ◽  
Ken Iesato ◽  
Mitsuhiro Abe ◽  
...  
2021 ◽  
Vol 49 ◽  

Herewith we would like to inform our readers that the final version of the article doi: 10.18786/2072-0505-2021- 49-001, published online on 02.03.2021, was replaced with a corrected version on 15.03.2021. The corrected version, according to the authors request, includes the following changes: the author list and the affiliations, authors' contributions, acknowledgements sections. The article should be cited as “Korb TA, Gavrilov PV, Chernina VYu, Blokhin IA, Aleshina OO, Mokienko OA, Morozov SP, Gombolevskiy VA. Specificity of chest computed tomography in COVID-19-associated pneumonia: a retrospective study. Almanac of Clinical Medicine. 2021;49. doi: 10.18786/2072-0505-2021-49-001.


2013 ◽  
Vol 52 (22) ◽  
pp. 2503-2509 ◽  
Author(s):  
Izaya Nakaya ◽  
Mayumi Yahata ◽  
Satoko Takahashi ◽  
Tomomi Sasajima ◽  
Tsutomu Sakuma ◽  
...  

Author(s):  
Arshed Hussain Parry ◽  
Abdul Haseeb Wani ◽  
Naveed Nazir Shah ◽  
Majid Jehangir

Abstract Background The data on medium-term follow-up of coronavirus disease-19 (COVID-19) pneumonia survivors is scarce. Medium-term follow-up will generate knowledge and help in devising a structured follow-up plan and to facilitate enrolment in clinical trials assessing the role of antifibrotic drugs in modifying the course of disease in order to avert long-term pulmonary sequelae of disease. The study was aimed to evaluate the lung findings on a medium-term follow-up (3 months or more) chest computed tomography (CT) in COVID-19 pneumonia survivors, assess the rate of resolution or persistence of lung abnormalities and to identify the initial demographic, clinical, and imaging characteristics that could potentially predict the persistence of lung abnormalities on follow-up. Results Out of the total study cohort of 81 patients, 46 (56.8%) demonstrated complete resolution of lung findings and the remaining 35 (43.2%) had residual lung opacities on follow-up CT. The most common type of residual abnormality was ground glass opacity (GGO) (16/35; 45.7%), followed by parenchymal bands (9/35; 25.7%), mixed pattern of GGO and parenchymal bands (6/35; 17.2%), bronchiectasis (6/35; 17.2%), and interlobular septal thickening (4/35; 11.4%). Patients with residual abnormalities were older, had higher BMI, more comorbidities, lower SpO2, longer hospital stay, higher rate of intensive care unit (ICU) admission, higher WBC count, a higher CT severity score, and lower rate of steroid administration with all p values < 0.05. Conclusion Nearly half of post-COVID-19 survivors had residual lung abnormalities after ≥ 3 months of follow-up. Certain clinico-radiological characteristics have the potential to identify the individuals at risk of having residual lung abnormalities on medium-term follow-up.


2021 ◽  
Author(s):  
Takashi Nawata ◽  
Natsu Kinoshita ◽  
Shinichi Okuda ◽  
Makoto Kubo ◽  
Yasuaki Wada ◽  
...  

ABSTRACT Objectives Microscopic polyangiitis (MPA) affects various organs. However, echocardiographic findings of MPA are unclear. We aimed to evaluate the echocardiographic features of acute-phase MPA in Japanese patients. Methods This single-centre retrospective study included 15 patients with MPA who underwent echocardiography within 2 weeks of commencing steroid therapy for induction or reinduction. The echocardiography parameters of thetients were compared with those of 30 age- and sex-matched controls. Results No significant differences in left ventricular (LV) diameter, LV ejection fraction, or e’ were observed between the two groups. However, the MPA group showed a significantly higher left atrial (LA) diameter and LA volume index, as well as higher early diastolic filling velocity, diastolic pulmonary venous flow velocity, and trans-tricuspid pressure gradient, and a shorter deceleration time (DCT). Serum C-reactive protein levels were positively correlated with E wave, E/A, and DCT. These results may indicate that increased LV stiffness, rather than impairment of LV relaxation, contributed to LV diastolic function, resulting in LA enlargement. Conclusions Patients with acute-phase MPA had LA dilatation associated with LV diastolic dysfunction. This finding indicates the importance of cardiac assessment in patients with MPA, especially in patients with a strong inflammatory reaction.


2020 ◽  
Vol 17 (3) ◽  
pp. 282
Author(s):  
ZaidHadi Hammoodi ◽  
HasanFalah Al-Khafaji ◽  
ZeidHamid Al-Murib ◽  
HussainKetab Al-Esawy ◽  
AliSalih Baiee ◽  
...  

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