Association of accelerated switch from vertebral end-plate Modic I to Modic 0 signal changes with clinical benefit of intradiscal corticosteroid injection for chronic low back pain

2011 ◽  
Vol 63 (9) ◽  
pp. 2828-2831 ◽  
Author(s):  
Christelle Nguyen ◽  
Marc Bénichou ◽  
Michel Revel ◽  
Serge Poiraudeau ◽  
François Rannou
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Clinical Benefit ◽  
Corticosteroid Injection ◽  
Low Back ◽  
End Plate ◽  
Signal Changes

scholarly journals High-sensitivity C-reactive protein in chronic low back pain with vertebral end-plate modic signal changes

2007 ◽  
Vol 57 (7) ◽  
pp. 1311-1315 ◽  
Author(s):  
François Rannou ◽  
Walid Ouanes ◽  
Isabelle Boutron ◽  
Bianca Lovisi ◽  
Fouad Fayad ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
High Sensitivity ◽  
Low Back ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
End Plate ◽  
Signal Changes

scholarly journals Treatment of degenerative chronic low back pain with fluoroscopically guided epidural procaine-corticosteroid injection

2008 ◽  
Vol 65 (7) ◽  
pp. 507-511 ◽  
Author(s):  
Slobodan Culafic ◽  
Dara Stefanovic ◽  
Dragan Dulovic ◽  
Ljubodrag Minic ◽  
Andrijana Culafic
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Conservative Therapy ◽  
Corticosteroid Injection ◽  
Pain Reduction ◽  
Lumbosacral Spine ◽  
Low Back ◽  
Military Medical Academy ◽  
Reduction Of Pain

Background/Aim. Low back pain is one of the most common painful conditions in the modern age. Therefore, it is very important to establish the most effective protocol for the treatment of this condition. The aim of this study was to find out if fluoroscopically, guided epidural procainecorticosteroid injection is effective in the treatment of degenerative chronic low back pain. Methods. This prospective cohort study was performed in the Military Medical Academy from September 2005 to June 2006 and included 60 patients of both sexes, 34-85 years of age. Degenerative changes of lumbosacral spine were determined by magnetic resonance imaging. The intensity of low back pain was evaluated by subjective (Roland's scale) and objective parameter (Lazarevic sign). Epidural procaine-corticosteroid injection was applied in the patients with low back pain not responding to conservative therapy. After the application of injection, effects of the therapy were followed up. Results. In 92% of the patients there was a reduction of pain intensity for three months, in 4.8% a reduction for a month, but after another injection they felt pain reduction for the next three months. One patient (2.3%) had pain reduction for one month. Conclusion. In the treatment of degenerative chronic low back pain, not responding to conservative therapy with nonsteroidal anti-inflammatory drugs, epidural procaine-corticosteroid injection have a satisfactory short-term as well as a long-term analgesic effect.

Epidural corticosteroid injection and amitriptyline for the treatment of chronic low back pain associated with radiculopathy

2003 ◽  
Vol 15 (3) ◽  
pp. 247-253 ◽  
Author(s):  
L. Pirbudak ◽  
G. Karakurum ◽  
U. Oner ◽  
A. Gulec ◽  
H. Karadasli
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Corticosteroid Injection ◽  
Low Back

Assessment of Ankylosing Spondylitis Criteria in Patients with Chronic Low Back Pain and Vertebral Endplate Modic I Signal Changes

2010 ◽  
Vol 37 (11) ◽  
pp. 2334-2339 ◽  
Author(s):  
CHRISTELLE NGUYEN ◽  
IMAD BENDEDDOUCHE ◽  
KATHERINE SANCHEZ ◽  
MARYLÈNE JOUSSE ◽  
AGATHE PAPELARD ◽  
...  
Keyword(s):  
Low Back Pain ◽  
Back Pain ◽  
Ankylosing Spondylitis ◽  
Chronic Low Back Pain ◽  
Tertiary Care ◽  
Low Back ◽  
Hla B27 ◽  
Vertebral Endplate ◽  
Mri Findings ◽  
Signal Changes

Objective.Patients with chronic low back pain (cLBP) and vertebral endplate Modic I signal changes on lumbar magnetic resonance imaging (MRI) have clinical features that could mimic inflammatory back pain related to spondyloarthritis (SpA) and/or ankylosing spondylitis (AS). We aimed to assess whether such patients fulfilled criteria for SpA and/or AS.Methods.For 5 months in 2008, all patients (n = 314) referred to a tertiary care physical medicine and rehabilitation facility in France were consecutively screened. A total of 185 hospitalized for non-specific cLBP were prospectively assessed. Forty patients fulfilling inclusion criteria were consecutively enrolled and included in 2 groups according to MRI findings: Modic I (n = 15) and non-Modic I (n = 25). MRI findings were assessed independently by 2 spine specialists and a radiologist. HLA-B27 status was determined. Data were collected on clinical measurements and fulfillment of Amor criteria (AC) and modified New York criteria (mNYC). All assessors were blinded to HLA-B27 status.Results.Whatever the Modic group, no patient fulfilled AC or mNYC, and mean total scores were comparable [3 ± 2 (range 0–22; p = 0.977), 1 ± 1 (range 0–3; p = 1.000), and 0 ± 0 (range 0–1; p = 1.000) for AC and clinical and radiological mNYC, respectively]. HLA-B27 status was similar in both groups [n = 2 (13%) vs n = 0 (0%); p = 0.135].Conclusion.Patients with cLBP and Modic I vertebral endplate signal changes on lumbar MRI do not fulfill widely used and validated criteria for SpA and/or AS. Such cases are clinically distinct from SpA and AS.

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