scholarly journals The influence of age at symptom onset and length of followup on mortality in patients with recent-onset inflammatory polyarthritis

2008 ◽  
Vol 58 (4) ◽  
pp. 985-989 ◽  
Author(s):  
Sophia M. Naz ◽  
Tracey M. Farragher ◽  
Diane K. Bunn ◽  
Deborah P. M. Symmons ◽  
Ian N. Bruce
Keyword(s):  
Symptom Onset ◽  
Recent Onset ◽  
Inflammatory Polyarthritis

Influence of age and sex on functional outcome over time in a cohort of patients with recent-onset inflammatory polyarthritis: Results from the Norfolk arthritis register

2011 ◽  
Vol 63 (12) ◽  
pp. 1745-1752 ◽  
Author(s):  
Elizabeth M. Camacho ◽  
Suzanne M. M. Verstappen ◽  
Mark Lunt ◽  
Diane K. Bunn ◽  
Deborah P. M. Symmons
Keyword(s):  
Functional Outcome ◽  
Recent Onset ◽  
Inflammatory Polyarthritis ◽  
Over Time ◽  
Age And Sex

scholarly journals Impending radiographic erosive progression over the following year in a cohort of consecutive patients with inflammatory polyarthritis: prediction by serum biomarkers

RMD Open ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. e001191 ◽  
Author(s):  
Nathalie Carrier ◽  
Artur J de Brum-Fernandes ◽  
Patrick Liang ◽  
Ariel Masetto ◽  
Sophie Roux ◽  
...  
Keyword(s):  
Positive Predictive Value ◽  
Treatment Strategies ◽  
Serum Biomarkers ◽  
C Reactive Protein ◽  
Recent Onset ◽  
Reactive Protein ◽  
Erosion Score ◽  
Erosive Progression ◽  
Generalised Estimating Equations ◽  
Inflammatory Polyarthritis

Background/PurposeTo evaluate biomarkers as predictors of impending erosion progression.MethodsVariables were measured at baseline and annually up to 5 years in patients with recent-onset polyarthritis treated to zero swollen joints. Erosive status was defined as ≥5 Units in Sharp/van der Heijde Erosion Score; Rapid Erosive Progression (REP) was defined as an increase ≥5 Units in Erosion Scores between consecutive visits. Generalised estimating equations (GEEs) evaluated the effect on REP of positive anticyclic citrullinated peptides (ACPAs) and/or rheumatoid factor (RF), C-reactive protein ˃8.0 mg/L (High-CRP) and 14-3-3η protein ≥0.50 ng/mL (High-14-3-3η), alone and in combinations.ResultsOut of 2155 evaluations in 749 consecutive patients, REP occurred after 186 (8.6%) visits, including 13 (2.2%) in patients recruited since 2010. Only 18/537 (3.4%; 6/411 (1.5%) in non-erosive vs 12/126 (9.5%) in patients already erosive) visits without any positive biomarker were followed by REP; at least one biomarker was positive prior to REP in 168/186 (90.3%) visits. Being positive for all four biomarkers conferred a positive predictive value (PPV) of 30.0% (RR 21.8) in patients non-erosive at the visit versus 35.5% (RR 3.07) in those already erosive. High-14-3-3η increased REP only in visits with High-CRP (eg, RR 2.5 to 3.9 when ACPA also positive) and in patients with non-erosive status (eg, RR from 4.3 to 9.4 when also High-CRP).ConclusionsAdding High-14-3-3η to positive antibodies and CRP improves prediction of impending REP. Although REP is becoming rarer, signatures of biomarkers might help to adapt treatment strategies in at-risk individuals, even those already erosive.

scholarly journals Predictors and outcomes of sustained, intermittent or never achieving remission in patients with recent onset inflammatory polyarthritis: results from the Norfolk Arthritis Register

Rheumatology ◽  
2016 ◽  
Vol 55 (9) ◽  
pp. 1601-1609 ◽  
Author(s):  
Michael J. Cook ◽  
Janet Diffin ◽  
Carlo A. Scirè ◽  
Mark Lunt ◽  
Alex J. MacGregor ◽  
...  
Keyword(s):  
Recent Onset ◽  
Inflammatory Polyarthritis

scholarly journals Outcomes in recent-onset inflammatory polyarthritis differ according to initial titers, persistence over time, and specificity of the autoantibodies

2010 ◽  
Vol 62 (11) ◽  
pp. 1624-1632 ◽  
Author(s):  
Marie-Caroline Guzian ◽  
Nathalie Carrier ◽  
Pierre Cossette ◽  
Artur J. de Brum-Fernandes ◽  
Patrick Liang ◽  
...  
Keyword(s):  
Recent Onset ◽  
Inflammatory Polyarthritis ◽  
Over Time

A recent onset inflammatory polyarthritis register in Spain: factors that predict remission

2007 ◽  
Vol 36 (5) ◽  
pp. 378-385 ◽  
Author(s):  
S. Reneses ◽  
L. Pestana ◽  
A. Fernandez‐Suarez ◽  
R. Criado ◽  
I. Wichmann ◽  
...  
Keyword(s):  
Recent Onset ◽  
Inflammatory Polyarthritis
Sign in / Sign up

Export Citation Format

Share Document