scholarly journals Bone density threshold and other predictors of vertebral fracture in patients receiving oral glucocorticoid therapy

2003 ◽  
Vol 48 (11) ◽  
pp. 3224-3229 ◽  
Author(s):  
T. P. Van Staa ◽  
R. F. Laan ◽  
I. P. Barton ◽  
S. Cohen ◽  
D. M. Reid ◽  
...  
Keyword(s):  
Vertebral Fracture ◽  
Bone Density ◽  
Glucocorticoid Therapy ◽  
Oral Glucocorticoid ◽  
Density Threshold

scholarly journals A154: Glucocorticoid Therapy and the Risk of Incident Vertebral Fracture in Children with Rheumatic Disorders

2014 ◽  
Vol 66 ◽  
pp. S199-S200 ◽  
Author(s):  
Claire M. A. LeBlanc ◽  
Jinhui Ma ◽  
Rosie Scuccimarri ◽  
David A. Cabral ◽  
Peter B. Dent ◽  
...  
Keyword(s):  
Vertebral Fracture ◽  
Glucocorticoid Therapy ◽  
Incident Vertebral Fracture

Comparison of efficacy and safety of parenteral versus parenteral and oral glucocorticoid therapy in Graves’ orbitopathy

2020 ◽  
Vol 74 (11) ◽  
Author(s):  
Biljana Nedeljkovic Beleslin ◽  
Jasmina Ciric ◽  
Mirjana Stojkovic ◽  
Slavica Savic ◽  
Tijana Lalic ◽  
...  
Keyword(s):  
Glucocorticoid Therapy ◽  
Efficacy And Safety ◽  
Oral Glucocorticoid ◽  
Graves Orbitopathy

scholarly journals Fracture risk with intermittent high-dose oral glucocorticoid therapy

2006 ◽  
Vol 56 (1) ◽  
pp. 208-214 ◽  
Author(s):  
Frank De Vries ◽  
Madelon Bracke ◽  
Hubert G. M. Leufkens ◽  
Jan-Willem J. Lammers ◽  
Cyrus Cooper ◽  
...  
Keyword(s):  
Fracture Risk ◽  
Glucocorticoid Therapy ◽  
High Dose ◽  
Oral Glucocorticoid ◽  
Dose Oral

Relationship Between Phalangeal Bone Density and Risk of Vertebral Fracture

2002 ◽  
Vol 5 (1) ◽  
pp. 11-15 ◽  
Author(s):  
Misako Ohtsuka ◽  
Daniel Michaeli ◽  
Richard D. Wasnich
Keyword(s):  
Vertebral Fracture ◽  
Bone Density ◽  
Phalangeal Bone

Effects of Oral Glucocorticoid Therapy on CD4+CD25+CD127- and CD4+CD25high T Cell Levels in Asthmatic Patients

Inflammation ◽  
2010 ◽  
Vol 33 (6) ◽  
pp. 415-420 ◽  
Author(s):  
Marcin Moniuszko ◽  
Anna Bodzenta-Lukaszyk ◽  
Milena Dabrowska
Keyword(s):  
T Cell ◽  
Glucocorticoid Therapy ◽  
Oral Glucocorticoid ◽  
Asthmatic Patients

Practice pattern variation in oral glucocorticoid therapy after the induction of response in proliferative lupus nephritis

Lupus ◽  
2010 ◽  
Vol 19 (5) ◽  
pp. 628-633 ◽  
Author(s):  
M. Walsh ◽  
D. Jayne ◽  
L. Moist ◽  
M. Tonelli ◽  
N. Pannu ◽  
...  
Keyword(s):  
Lupus Nephritis ◽  
Glucocorticoid Therapy ◽  
Practice Pattern ◽  
Oral Glucocorticoid ◽  
Proliferative Lupus Nephritis

Prevalence of vertebral fracture in women and the relationship with bone density and symptoms: The chingford study

2009 ◽  
Vol 8 (7) ◽  
pp. 817-822 ◽  
Author(s):  
Tim D. Spector ◽  
Eugene V. Mccloskey ◽  
David V. Doyle ◽  
John A. Kanis
Keyword(s):  
Vertebral Fracture ◽  
Bone Density ◽  
The Relationship

Bone Microarchitecture Assessment by High-Resolution Peripheral Quantitative Computed Tomography in Patients with Systemic Lupus Erythematosus Taking Corticosteroids

2010 ◽  
Vol 37 (7) ◽  
pp. 1473-1479 ◽  
Author(s):  
EDMUND K. LI ◽  
TRACY Y. ZHU ◽  
LAI-SHAN TAM ◽  
VIVIAN W. HUNG ◽  
JAMES F. GRIFFITH ◽  
...  
Keyword(s):  
Vertebral Fracture ◽  
Bone Density ◽  
Cortical Bone ◽  
Vertebral Fractures ◽  
Lupus Erythematosus ◽  
Bone Microarchitecture ◽  
Quantitative Computed Tomography ◽  
Peripheral Quantitative Computed Tomography ◽  
Cortical Bone Density ◽  
Chronic Corticosteroid

Objective.We assessed the relationship between vertebral fracture and bone microarchitecture in patients with systemic lupus erythematosus (SLE) on chronic corticosteroid therapy using high-resolution peripheral quantitative computed tomography (HR-pQCT).Methods.Fifty-nine Chinese women with SLE taking corticosteroid were selected to participate in a cross-sectional study. Vertebral fracture was confirmed semiquantitatively by lateral radiographs of the thoracic and lumbar spine. Density and microarchitecture at the distal radius were measured with HR-pQCT. Areal bone mineral density (aBMD) at hip and lumbar spine was measured by dual-energy x-ray absorptiometry (DEXA).Results.Twelve patients had vertebral fractures. The aBMD of spine or hip did not differ between those with and without vertebral fractures. Measures by HR-pQCT revealed that patients with vertebral fractures had significantly lower level of average bone density (p = 0.007), cortical bone density (p = 0.029), trabecular bone density (p = 0.024), trabecular bone volume to tissue volume (p = 0.023), and trabecular thickness (p = 0.011) than those without vertebral fractures. Independent explanatory variables associated with higher risk of vertebral fractures were older age (p = 0.013) and lower average cortical bone density (p = 0.029).Conclusion.Vertebral fracture in patients with SLE on chronic corticosteroid treatment was associated with alterations of bone density and microarchitectures measured by HR-pQCT and DEXA. However, alterations were more pronounced in measurements by HR-pQCT. Low cortical bone density and old age were significant predictors of vertebral fracture risk.

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