In vitro self-assembly of proepicardial cell aggregates: An embryonic vasculogenic model for vascular tissue engineering

2006 ◽  
Vol 288A (7) ◽  
pp. 700-713 ◽  
Author(s):  
José M. Pérez-Pomares ◽  
V. Mironov ◽  
Juan A. Guadix ◽  
David Macías ◽  
Roger R. Markwald ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Self Assembly ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Cell Aggregates

Surface Modification by Nanobiomaterials for Vascular Tissue Engineering Applications

2020 ◽  
Vol 27 (10) ◽  
pp. 1634-1646 ◽  
Author(s):  
Huey-Shan Hung ◽  
Shan-hui Hsu
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Thrombus Formation ◽  
Vascular Grafts ◽  
Vascular Tissue Engineering ◽  
Great Success ◽  
Natural Polymers ◽  
Vascular Biomaterials

Treatment of cardiovascular disease has achieved great success using artificial implants, particularly synthetic-polymer made grafts. However, thrombus formation and restenosis are the current clinical problems need to be conquered. New biomaterials, modifying the surface of synthetic vascular grafts, have been created to improve long-term patency for the better hemocompatibility. The vascular biomaterials can be fabricated from synthetic or natural polymers for vascular tissue engineering. Stem cells can be seeded by different techniques into tissue-engineered vascular grafts in vitro and implanted in vivo to repair the vascular tissues. To overcome the thrombogenesis and promote the endothelialization effect, vascular biomaterials employing nanotopography are more bio-mimic to the native tissue made and have been engineered by various approaches such as prepared as a simple surface coating on the vascular biomaterials. It has now become an important and interesting field to find novel approaches to better endothelization of vascular biomaterials. In this article, we focus to review the techniques with better potential improving endothelization and summarize for vascular biomaterial application. This review article will enable the development of biomaterials with a high degree of originality, innovative research on novel techniques for surface fabrication for vascular biomaterials application.

Hemocompatibility evaluation of poly(glycerol-sebacate) in vitro for vascular tissue engineering

Biomaterials ◽  
2006 ◽  
Vol 27 (24) ◽  
pp. 4315-4324 ◽  
Author(s):  
Delara Motlagh ◽  
Jian Yang ◽  
Karen Y. Lui ◽  
Antonio R. Webb ◽  
Guillermo A. Ameer
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering

Hemocompatibility evaluation of poly(diol citrate)in vitro for vascular tissue engineering

2007 ◽  
Vol 82A (4) ◽  
pp. 907-916 ◽  
Author(s):  
Delara Motlagh ◽  
Josephine Allen ◽  
Ryan Hoshi ◽  
Jian Yang ◽  
Karen Lui ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering

scholarly journals Vascular Tissue Engineering: Polymers and Methodologies for Small Caliber Vascular Grafts

2021 ◽  
Vol 7 ◽  
Author(s):  
Bruna B. J. Leal ◽  
Naohiro Wakabayashi ◽  
Kyohei Oyama ◽  
Hiroyuki Kamiya ◽  
Daikelly I. Braghirolli ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Thrombus Formation ◽  
Treatment Options ◽  
Vascular Grafts ◽  
Vascular Tissue Engineering ◽  
Engineering Polymers ◽  
Autologous Grafts

Cardiovascular disease is the most common cause of death in the world. In severe cases, replacement or revascularization using vascular grafts are the treatment options. While several synthetic vascular grafts are clinically used with common approval for medium to large-caliber vessels, autologous vascular grafts are the only options clinically approved for small-caliber revascularizations. Autologous grafts have, however, some limitations in quantity and quality, and cause an invasiveness to patients when harvested. Therefore, the development of small-caliber synthetic vascular grafts (<5 mm) has been urged. Since small-caliber synthetic grafts made from the same materials as middle and large-caliber grafts have poor patency rates due to thrombus formation and intimal hyperplasia within the graft, newly innovative methodologies with vascular tissue engineering such as electrospinning, decellularization, lyophilization, and 3D printing, and novel polymers have been developed. This review article represents topics on the methodologies used in the development of scaffold-based vascular grafts and the polymers used in vitro and in vivo.

Beware of interspecies differences in vascular tissue engineering: in vitro and in vivo discrepancies

2013 ◽  
Vol 22 (3) ◽  
pp. e40
Author(s):  
Murielle Rémy ◽  
Patrick Menu ◽  
J.C. Voegel ◽  
J.F. Ponsot ◽  
M.F. Harmand ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Interspecies Differences

Vascular Tissue Regeneration of the Hybrid ePTFE Graft for Adult Patients

2005 ◽  
Vol 288-289 ◽  
pp. 55-58 ◽  
Author(s):  
In Sup Noh
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Tissue Regeneration ◽  
Vascular Graft ◽  
Vascular Tissue ◽  
Vascular Tissue Engineering ◽  
Tissue Formation ◽  
High Demand ◽  
Eptfe Graft

Vascular Tissue engineering has drawn high interest due to its high demand in its vascular graft applications. We tissue-engineered a hybrid vascular graft consisting of tissues layers and non-biodegradable ePTFE by in vitro cell culture. Tissue formation was obtained by culturing vascular smooth muscle cells on the biodegradable polylactide scaffolds on the ePTFE surfaces. The fabricated hybrid ePTFE graft consisted of three layers, i.e. two biodegradable polylactide layers and a non-biodegradable ePTFE layer. The biodegradable layer was fabricated to have a porous structure with 30-60 µm pore sizes. Connection of biodegradable layers and ePTFE was obtained by filtering the polylactide solution through the porous ePTFE wall. For a better tissue formation coating of gelatin was performed on the luminal polylactide scaffolds. The generated tissues replaced the biodegradable layers on both inside and outside surfaces of the ePTFE.

Sign in / Sign up

Export Citation Format

Share Document