scholarly journals Presence of Galanin-Like Immunoreactivity in Mesenchymal and Neural Crest Origin Tissues During Embryonic Development in the Mouse

2009 ◽  
Vol 292 (4) ◽  
pp. 481-487 ◽  
Author(s):  
Melissa Jones ◽  
Paul Perumal ◽  
Maria Vrontakis
Keyword(s):  
Embryonic Development ◽  
Neural Crest ◽  
Neural Crest Origin

The Distribution of Sulphur in the Differentiating Visceral Cartilage of Xenopus

Development ◽  
1960 ◽  
Vol 8 (1) ◽  
pp. 54-59
Author(s):  
T. S. Okada ◽  
J. L. Sirlin
Keyword(s):  
Embryonic Development ◽  
Neural Crest ◽  
Early Embryo ◽  
Embryonic Tissues ◽  
Early Embryos ◽  
Neural Crest Origin ◽  
Different Tissues

During embryonic development the differentiation of different tissues depends largely on the synthesis of specific substances characteristic of each tissue. From this viewpoint it is of interest to study the uptake of sulphur by the early embryo, especially since the incorporation and retention of this isotope in sulpho-muco-polysaccharides has now been well established by various authors working on fully differentiated tissues (see review by Dziewiatkowski, 1958). So far some work has been done on the distribution of radiosulphate in early embryos (Amprino, 1955 a, b; Friberg & Ringertz, 1956; Johnston & Comar, 1957), but for amphibians in particular no information is yet available. The present paper deals with the incorporation of radiosulphate in various embryonic tissues of Xenopus, in particular in the visceral cartilage of ectomesodermal (neural crest) origin. Embryos of X. laevis in stages 29–47 (Nieuwkoop & Faber, 1956) were used.

An experimental study on neural crest migration in Barbus conchonius (Cyprinidae, Teleostei), with special reference to the origin of the enteroendocrine cells

Development ◽  
1981 ◽  
Vol 62 (1) ◽  
pp. 309-323
Author(s):  
C. H. J. Lamers ◽  
J. W. H. M. Rombout ◽  
L. P. M. Timmermans
Keyword(s):  
Neural Crest ◽  
Neural Tube ◽  
Ganglion Cells ◽  
Neural Crest Cells ◽  
Enteroendocrine Cells ◽  
Pigment Cells ◽  
Transplantation Technique ◽  
Spinal Ganglion Cells ◽  
Neural Crest Origin ◽  
Neural Crest Migration

A neural crest transplantation technique is described for fish. As in other classes ofvertebrates, two pathways of neural crest migration can be distinguished: a lateroventral pathway between somites and ectoderm, and a medioventral pathway between somites and neural tube/notochord. In this paper evidence is presented for a neural crest origin of spinal ganglion cells and pigment cells, and indication for such an origin is obtained for sympathetic and enteric ganglion cells and for cells that are probably homologues to adrenomedullary and paraganglion cells in the future kidney area. The destiny of neural crest cells near the developing lateral-line sense organs is discussed. When grafted into the yolk, neural crest cells or neural tube cells appear to differentiate into ‘periblast cells’; this suggests a highly activating influence of the yolk. Many neural crest cells are found around the urinary ducts and, when grafted below the notochord, even within the urinary duct epithelium. These neural crest cells do not invade the gut epithelium, even when grafted adjacent to the developing gut. Consequently enteroendocrine cells in fish are not likely to have a trunkor rhombencephalic neural crest origin. Another possible origin of these cells will be proposed.

scholarly journals Synergy of Nf2 and p53 mutations in development of malignant tumours of neural crest origin

Oncogene ◽  
2004 ◽  
Vol 23 (39) ◽  
pp. 6541-6547 ◽  
Author(s):  
Els Robanus-Maandag ◽  
Marco Giovannini ◽  
Martin van der Valk ◽  
Michiko Niwa-Kawakita ◽  
Vincent Abramowski ◽  
...  
Keyword(s):  
Neural Crest ◽  
P53 Mutations ◽  
Malignant Tumours ◽  
Neural Crest Origin

On the track of a human circulating mesenchymal stem cell of neural crest origin

2000 ◽  
Vol 54 (3) ◽  
pp. 146-162 ◽  
Author(s):  
M.L. Labat ◽  
G. Milhaud ◽  
M. Pouchelet ◽  
P. Boireau
Keyword(s):  
Stem Cell ◽  
Mesenchymal Stem Cell ◽  
Neural Crest ◽  
Neural Crest Origin

The developmental fate of the cephalic mesoderm in quail-chick chimeras

Development ◽  
1992 ◽  
Vol 114 (1) ◽  
pp. 1-15 ◽  
Author(s):  
G.F. Couly ◽  
P.M. Coltey ◽  
N.M. Le Douarin
Keyword(s):  
Neural Crest ◽  
Neural Crest Cells ◽  
Paraxial Mesoderm ◽  
Avian Embryo ◽  
Facial Skeleton ◽  
Developmental Fate ◽  
Prechordal Mesoderm ◽  
The Face ◽  
Neural Crest Origin ◽  
Neurula Stage

The developmental fate of the cephalic paraxial and prechordal mesoderm at the late neurula stage (3-somite) in the avian embryo has been investigated by using the isotopic, isochronic substitution technique between quail and chick embryos. The territories involved in the operation were especially tiny and the size of the transplants was of about 150 by 50 to 60 microns. At that stage, the neural crest cells have not yet started migrating and the fate of mesodermal cells exclusively was under scrutiny. The prechordal mesoderm was found to give rise to the following ocular muscles: musculus rectus ventralis and medialis and musculus oblicus ventralis. The paraxial mesoderm was separated in two longitudinal bands: one median, lying upon the cephalic vesicles (median paraxial mesoderm—MPM); one lateral, lying upon the foregut (lateral paraxial mesoderm—LPM). The former yields the three other ocular muscles, contributes to mesencephalic meninges and has essentially skeletogenic potencies. It contributes to the corpus sphenoid bone, the orbitosphenoid bone and the otic capsules; the rest of the facial skeleton is of neural crest origin. At 3-somite stage, MPM is represented by a few cells only. The LPM is more abundant at that stage and has essentially myogenic potencies with also some contribution to connective tissue. However, most of the connective cells associated with the facial and hypobranchial muscles are of neural crest origin. The more important result of this work was to show that the cephalic mesoderm does not form dermis. This function is taken over by neural crest cells, which form both the skeleton and dermis of the face. If one draws a parallel between the so-called “somitomeres” of the head and the trunk somites, it appears that skeletogenic potencies are reduced in the former, which in contrast have kept their myogenic capacities, whilst the formation of skeleton and dermis has been essentially taken over by the neural crest in the course of evolution of the vertebrate head.

The Occurrence and Morphogenesis of Melanocytes in the Connective Tissues of the PET/MCV Mouse Strain1

Development ◽  
1960 ◽  
Vol 8 (1) ◽  
pp. 24-32
Author(s):  
Stuart E. Nichols ◽  
Willie M. Reams
Keyword(s):  
Neural Crest ◽  
The Body ◽  
Connective Tissues ◽  
Medical College ◽  
Genital Apparatus ◽  
Mouse Tissues ◽  
Harderian Glands ◽  
Neural Crest Origin ◽  
The Brain ◽  
Made In

Mammals, as a rule, are described as having melanocytes of neural crest origin confined almost entirely to the skin. Of the organs other than skin which have been described as possessing melanocytes are portions of the gonado-genital apparatus of the Opossum (Burns, 1939), and, in the house mouse, tissues of the nictitans, the meninges of the brain, the parathyroids, the thymus and harderian glands (Markert & Silvers, 1956), and the parathyroids of C58 mice (Dunn, 1949). The present investigation has been made in a strain of mice in which melanocytes are found in the connective tissues throughout much of the body. This strain originated several years ago in the Department of Genetics, Medical College of Virginia, from a cross between inbred C3H and black mice of unknown breed obtained from a local pet shop. Because of the latter circumstance, the line-bred progeny have been termed the PET/MCV strain.

DeltaEF1, a zinc finger and homeodomain transcription factor, is required for skeleton patterning in multiple lineages

Development ◽  
1998 ◽  
Vol 125 (1) ◽  
pp. 21-31 ◽  
Author(s):  
T. Takagi ◽  
H. Moribe ◽  
H. Kondoh ◽  
Y. Higashi
Keyword(s):  
Neural Crest ◽  
Zinc Finger ◽  
Intervertebral Discs ◽  
Regulatory Function ◽  
Craniofacial Abnormalities ◽  
Tarsal Bone ◽  
Skeletal Defects ◽  
Neural Crest Origin ◽  
Brain And Spinal Cord ◽  
The Brain

DeltaEF1 is a DNA binding protein containing a homeodomain and two zinc finger clusters, and is regarded as a vertebrate homologue of zfh-1 (zinc finger homeodomain-containing factor-1) in Drosophila. In the developing embryo, deltaEF1 is expressed in the notochord, somites, limb, neural crest derivatives and a few restricted sites of the brain and spinal cord. To elucidate the regulatory function of deltaEF1 in mouse embryogenesis, we generated deltaEF1 null mutant (deltaEF1null(lacZ)) mice. The deltaEF1null(lacZ) homozygotes developed to term, but never survived postnatally. In addition to severe T cell deficiency of the thymus, the deltaEF1null(lacZ) homozygotes exhibited skeletal defects of various lineages. (1) Craniofacial abnormalities of neural crest origin: cleft palate, hyperplasia of Meckel's cartilage, dysplasia of nasal septum and shortened mandible. (2) Limb defects: shortening and broadening of long bones, fusion of carpal/tarsal bone and fusion of joints. (3) Fusion of ribs. (4) Sternum defects: split and asymmetric ossification pattern of the sternebrae associated with irregular sternocostal junctions. (5) Hypoplasia of intervertebral discs. These results indicate that deltaEF1 has an essential role in regulating development of these skeletal structures. Since the skeletal defects were not observed in deltaEF1deltaC727 mice, deltaEF1 bears distinct regulatory activities which are dependent on different domains of the molecule.

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