Effect of cyproterone acetate on structure and function of rhesus monkey reproductive organs

1992 ◽  
Vol 234 (1) ◽  
pp. 62-72 ◽  
Author(s):  
Jagdeep Kaur ◽  
P. R. Ramakrishnan ◽  
M. Rajalakshmi
Author(s):  
Nabil A. Khouri ◽  
Haytham M. Daradka ◽  
Mohammed Z. Allouh ◽  
Ahmad S. Alkofahi

Abstract: The effects of: Both plants were administered orally to two separate mice groups at a dose of 800 mg/kg/day for 35 days and compared with control group. After treatment, 5 mice of each group were sacrificed and total mice weights, reproductive organs’ weights, spermatogenesis, and androgenic serum markers were investigated. The remaining mice from all groups were allowed to mate with virgin female mice to explore male fertility potential.: Results indicated that body and organs’ weights were increased significantly in mice treated with: We can conclude that


Endocrinology ◽  
2001 ◽  
Vol 142 (6) ◽  
pp. 2435-2442 ◽  
Author(s):  
Xiangdong Li ◽  
Elina Nokkala ◽  
Wei Yan ◽  
Tomi Streng ◽  
Niina Saarinen ◽  
...  

2004 ◽  
Vol 101 (13) ◽  
pp. 4685-4689 ◽  
Author(s):  
L. T. Goldsmith ◽  
G. Weiss ◽  
S. Palejwala ◽  
T. M. Plant ◽  
A. Wojtczuk ◽  
...  

Toxics ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 94
Author(s):  
Peter Massányi ◽  
Martin Massányi ◽  
Roberto Madeddu ◽  
Robert Stawarz ◽  
Norbert Lukáč

Reproductive organs are essential not only for the life of an individual but also for the survival and development of the species. The response of reproductive organs to toxic substances differs from that of other target organs, and they may serve as an ideal “barometer” for the deleterious effects of environmental pollution on animal and human health. The incidence of infertility, cancers, and associated maladies has increased in the last fifty years or more, while various anthropogenic activities have released into the environment numerous toxic substances, including cadmium, lead, and mercury. Data from epidemiological studies suggested that environmental exposure to cadmium, lead, and mercury may have produced reproductive and developmental toxicity. The present review focused on experimental studies using rats, mice, avian, and rabbits to demonstrate unambiguously effects of cadmium, lead, or mercury on the structure and function of reproductive organs. In addition, relevant human studies are discussed. The experimental studies reviewed have indicated that the testis and ovary are particularly sensitive to cadmium, lead, and mercury because these organs are distinguished by an intense cellular activity, where vital processes of spermatogenesis, oogenesis, and folliculogenesis occur. In ovaries, manifestation of toxicity induced by cadmium, lead, or mercury included decreased follicular growth, occurrence of follicular atresia, degeneration of the corpus luteum, and alterations in cycle. In testes, toxic effects following exposure to cadmium, lead, or mercury included alterations of seminiferous tubules, testicular stroma, and decrease of spermatozoa count, motility and viability, and aberrant spermatozoa morphology.


Sign in / Sign up

Export Citation Format

Share Document