The effects of prostaglandin F2? on the fine structure of the corpus luteum of the hysterectomized guinea pig

1975 ◽  
Vol 183 (2) ◽  
pp. 229-241 ◽  
Author(s):  
J. N. Bagwell ◽  
D. L. Davies ◽  
J. R. Ruby
1971 ◽  
Vol 115 (4) ◽  
pp. 473-493 ◽  
Author(s):  
Paula R. Crombie ◽  
Robert D. Burton ◽  
Nicola Ackland
Keyword(s):  

1989 ◽  
Vol 108 (1-2) ◽  
pp. 26-30 ◽  
Author(s):  
Toshihiko Kikuchi ◽  
Tomonori Takasaka ◽  
Akira Tonosaki ◽  
Hiroshi Watanabe
Keyword(s):  

1954 ◽  
Vol 43 (sup116) ◽  
pp. 298-303 ◽  
Author(s):  
Jan Wersäll ◽  
Hans Engström ◽  
Sture Hjorth

1982 ◽  
Vol 24 (4) ◽  
pp. 519-526 ◽  
Author(s):  
T.I. Azmi ◽  
J.D. O'Shea ◽  
C.S. Lee ◽  
r.J. Rodgers

1973 ◽  
Vol 115 (7) ◽  
pp. 901-911 ◽  
Author(s):  
Thomas M. Crisp ◽  
Dessouky A. Dessouky ◽  
Francis R. Denys

1972 ◽  
Vol 55 (3) ◽  
pp. 599-607 ◽  
Author(s):  
B. T. DONOVAN ◽  
A. N. LOCKHART

SUMMARY The release of ovulating hormone after acute treatment with gonadal steroids, or corpus luteum removal on different days of the oestrous cycle, was studied in the guinea-pig. Injection of 25, 50 or 100 μg oestradiol or 2·5 mg progesterone on day 13 of the cycle had no effect upon gonadotrophin secretion as judged by follicular histology, but markedly altered the sizes of the corpora lutea of the previous ovulation. Treatment with oestradiol on day 14 did not elicit gonadotrophin secretion. However, administration of the same hormones to animals given 10 μg oestradiol benzoate 24 h earlier caused ovulation or follicular luteinization. Progesterone (2·5 mg) appeared least effective in stimulating gonadotrophin release; 25 μg oestradiol were more effective when given at 12.00 h than at 24.00 h but treatment with both hormones caused ovulation when given at either time of day. Luteal volumes were not affected. Removal of corpora lutea during the second half of the cycle advanced the time of expected ovulation to day 15 or earlier when the procedure was carried out on days 8 or 9, but not on days 10–13. It is concluded that 4–5 days must elapse between the fall in plasma progesterone level associated with corpus luteum regression and the release of ovulating hormone.


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