Cytochemical study of the physiological activities in the pars intermedia of Rana pipiens

1954 ◽  
Vol 119 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Robert Ortman
Keyword(s):  
Rana Pipiens ◽  
Pars Intermedia ◽  
Cytochemical Study

A CYTOCHEMICAL STUDY OF THE ABSORPTION AND DISTRIBUTION OF IRON IN THE FROG, RANA PIPIENS

1950 ◽  
Vol 28d (3) ◽  
pp. 119-125 ◽  
Author(s):  
David J. McCallion ◽  
Joseph L. Scott
Keyword(s):  
Intestinal Mucosa ◽  
Large Dose ◽  
Metallic Iron ◽  
Rana Pipiens ◽  
Stellate Cells ◽  
Ferric Sulphate ◽  
Maximum Condition ◽  
Liver Iron ◽  
Cytochemical Study ◽  
Free Iron

Cytochemical studies for iron in starved frogs fed a single large dose (50 to 200 mgm.) of ferric sulphate or metallic iron showed that free iron was most readily absorbed by the intestinal mucosa of the duodenum. Liver iron increased slightly two hours after feeding, reached a maximum condition after six hours, and decreased considerably by 12 hr. The increased liver iron was found in the Kuppfer cells, the lining cells of the sinusoids, and the stellate cells of the pigment patches. Iron in the liver of control frogs was usually confined to the pigment patches. After ferric sulphate solution was fed there was an increase in the amount of free iron in the spleen and in the liver but not in the kidney. There was a marked increase in masked iron in the nuclei of the cells of the liver and spleen, and even in those of the kidney of these same animals.

Neuropeptide Y does not inhibit the release of α-MSH from the pars intermedia of the rat adenohypophysis

1988 ◽  
Vol 66 (3) ◽  
pp. 318-320 ◽  
Author(s):  
J. Kraicer ◽  
B. Lussier ◽  
S. Kotanen ◽  
B. C. Moor
Keyword(s):  
Neuropeptide Y ◽  
Rana Pipiens ◽  
Pars Intermedia ◽  
Regulatory Peptide

Neuropeptide Y in concentrations from 10−8 to 10−6 M inhibits the release of α-MSH from the frog (Rana pipiens) pituitary in a reversible, sustained, and concentration-related manner. However, it does not inhibit the release of α-MSH from the rat pars intermedia. Thus, while neuropeptide Y may play a role in the control of α-MSH release in amphibia, it appears not to be a regulatory peptide for the mammalian pars intermedia.

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