The ovary of the adult rat. I. Changes in growth of the follicle and in volume and mitotic activity of the granulosa and theca during the estrous cycle

1939 ◽  
Vol 73 (4) ◽  
pp. 429-442 ◽  
Author(s):  
Charles E. Lane ◽  
Forrest R. Davis
Keyword(s):  
Mitotic Activity ◽  
Estrous Cycle ◽  
Adult Rat

Mullerian Inhibiting Substance in the Adult Rat Ovary During Various Stages of the Estrous Cycle*

Endocrinology ◽  
1989 ◽  
Vol 125 (2) ◽  
pp. 1060-1066 ◽  
Author(s):  
SHIGERU UENO ◽  
TATSUO KURODA ◽  
DAVID T. MACLAUGHLIN ◽  
RICHARD C. RAGIN ◽  
THOMAS F. MANGANARO ◽  
...  
Keyword(s):  
Estrous Cycle ◽  
Adult Rat ◽  
Müllerian Inhibiting Substance ◽  
Rat Ovary ◽  
Mullerian Inhibiting Substance

Role of Ghrelin on Estrogen and Progesterone Secretion in the Adult Rat Ovary During Estrous Cycle

2011 ◽  
Vol 58 (2) ◽  
pp. 116-119 ◽  
Author(s):  
Fugui Fang ◽  
Lin Wang ◽  
Yunhai Zhang ◽  
Yunsheng Li ◽  
Shiping Su ◽  
...  
Keyword(s):  
Estrous Cycle ◽  
Adult Rat ◽  
Progesterone Secretion ◽  
Rat Ovary

scholarly journals Temporally Sensitive Trophic Responsiveness of the Adrenalectomized Rat Anterior Pituitary to Dexamethasone Challenge: Relationship between Mitotic Activity and Apoptotic Sensitivity

Endocrinology ◽  
2003 ◽  
Vol 144 (1) ◽  
pp. 212-219 ◽  
Author(s):  
L. A. Nolan ◽  
A. Levy
Keyword(s):  
Cell Cycle ◽  
Mitotic Activity ◽  
Cell Population ◽  
Anterior Pituitary ◽  
Apoptotic Cell ◽  
Apoptotic Response ◽  
Adult Rat ◽  
Step Down ◽  
Induced Apoptosis ◽  
Persistent Elevation

Abstract Depending on timing and dose, exogenous glucocorticoids induce a wave of apoptosis in the adult rat anterior pituitary, a response that is enhanced by adrenalectomy. In this study, we show that the size of the glucocorticoid-sensitive apoptotic population progressively increases during the week following surgical adrenalectomy, plateaus for a further week, then spontaneously declines to levels seen in intact animals by 4 wk. Mitotic activity, in contrast, rises rapidly post adrenalectomy but returns to baseline within 2 wk. Increased mitotic activity precedes the increase in the population of cells that undergo glucocorticoid-induced apoptosis and the subsequent decline in mitotic activity precedes the decline in apoptotic sensitivity despite persistent elevation of hypothalamic CRH and pituitary proopiomelanocortin transcripts. If glucocorticoid exposure is delayed until 4 wk post adrenalectomy when the apoptotic response has returned to baseline, glucocorticoid withdrawal, by transiently increasing mitotic activity, again primes the formation of an expanded glucocorticoid-sensitive apoptotic cell population. These data suggest that apoptotic sensitivity is largely confined to cells that have recently entered the cell cycle. This observation is further corroborated by demonstrating an abrupt glucocorticoid-induced step-down in the bromodeoxyuridine-labeling index to basal levels in rats given daily injections of bromodeoxyuridine during the week following adrenalectomy.

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