Effect of CaO in the thermal crosslinking of maltodextrin and citric acid: A cooperative action of condensation and ionic interactions

2016 ◽  
Vol 133 (46) ◽  
Author(s):  
M. Castro-Cabado ◽  
A.L. Casado ◽  
J. San Román
Keyword(s):  
Citric Acid ◽  
Ionic Interactions ◽  
Cooperative Action ◽  
Thermal Crosslinking

scholarly journals Catalyst-Free Crosslinking Modification of Nata-de-Coco-Based Bacterial Cellulose Nanofibres Using Citric Acid for Biomedical Applications

Polymers ◽  
2021 ◽  
Vol 13 (17) ◽  
pp. 2966
Author(s):  
Rabiu Salihu ◽  
Mohamed Nainar Mohamed Ansari ◽  
Saiful Izwan Abd Razak ◽  
Nurliyana Ahmad Zawawi ◽  
Shafinaz Shahir ◽  
...  
Keyword(s):  
Citric Acid ◽  
Bacterial Cellulose ◽  
Materials Science ◽  
Tensile Modulus ◽  
Wound Dressings ◽  
Crosslinking Reaction ◽  
Catalyst Free ◽  
Thermal Crosslinking ◽  
Cellulose Nanofibres ◽  
Tissue Scaffolding

Bacterial cellulose (BC) has gained attention among researchers in materials science and bio-medicine due to its fascinating properties. However, BC’s fibre collapse phenomenon (i.e., its inability to reabsorb water after dehydration) is one of the drawbacks that limit its potential. To overcome this, a catalyst-free thermal crosslinking reaction was employed to modify BC using citric acid (CA) without compromising its biocompatibility. FTIR, XRD, SEM/EDX, TGA, and tensile analysis were carried out to evaluate the properties of the modified BC (MBC). The results confirm the fibre crosslinking phenomenon and the improvement of some properties that could be advantageous for various applications. The modified nanofibre displayed an improved crystallinity and thermal stability with increased water absorption/swelling and tensile modulus. The MBC reported here can be used for wound dressings and tissue scaffolding.

ENHANCED ASSOCIATION OF FIBRINOGEN WITH ITS PLATELET RECEPTOR DUE TO SODIUM CITRATE INDICATION FOR ONE FIBRINOGEN RECEPTOR ONLY

1987 ◽  
Author(s):  
S X Bowry
Keyword(s):  
Citric Acid ◽  
Binding Sites ◽  
Sodium Citrate ◽  
Specific Binding ◽  
Ionic Interactions ◽  
Single Class ◽  
Washed Platelet ◽  
Fibrinogen Receptor ◽  
Platelet Receptor ◽  
Scatchard Plots

Washed platelet suspensions are almost always prepared from blood anticoagulated with sodium citrate. As citrate has been implicated to affect platelet function and as estimates of the number of fibrinogen (Fbg) bindingsites on platelets range from 4,700 -82,500, we examined the involvement of citrate on the platelet-fibrinogen interaction. The binding of 125-1-fibrinogen to washed platelets from citrated blood (PCB) and thosefrom gel-filtered non-anticoagulated blood (PNB) from the same donor showed linear Scatchard plots for PNB and curvilinear plots for PCB. Assuming the presence of two classes of bindingsites, a high_.affinity site (5,540±760 molecules/ platelets; Kd, 1.29 x 10-7 M) and low affinity site (32,070 α 6,520 molecules/platelet; Kd 1.02 x 10-6 M) were determined for PCB. However, PNB indicated a single class of binding sites with 16,480α 2,800 Fbg molecules/platelet.When blood from one donor was collected into 10 mM and 20 mM citrate, increased binding of Fbg was observed onplatelets exposed to 20 mM citrate. The effects of citrate appear to be on theplatelet Fbg receptor since non-specific binding was not affected by the citrate. As no 14-C-citric acid binding to platelets was observed, citrate may affect the receptors without binding to the platelets. The dependence of binding on the pHof thecitrate suggests ionic interactions between platelets and citrate. Different amounts of Fbg were bound when four different preparations of sodium citrate varying in concentration and pH were used. Ourdata suggest that acombination of thedirect effects of citrate on the Fbg bindingof platelets, together with the variable concentrations and pH of the different citrate preparations routinelyused toanticoagulate blood, may explain why some investigators obtain upwardly concave Scatchard plotswhile others obtain linear plots. Ourresultsindicate that the major reasonfor the disparities in the Fbg binding datais due to the effects of citrate on platelets.

Coadministration of citric acid allows oxytetracycline dose reduction in yellowtail Seriola quinqueradiata infected with Vibrio anguillarum

2020 ◽  
Vol 140 ◽  
pp. 25-29
Author(s):  
K Akiyama ◽  
N Hirazawa ◽  
A Hatanaka
Keyword(s):  
Body Weight ◽  
Citric Acid ◽  
Effective Treatment ◽  
Dose Reduction ◽  
Vibrio Anguillarum ◽  
Enhancing Effect ◽  
Bacterial Diseases ◽  
Seriola Quinqueradiata ◽  
Poor Efficacy

Oxytetracycline (OTC) has been commonly used as an effective antibiotic against various fish bacterial diseases, including vibriosis. In this study, the absorption-enhancing effect of citric acid on oral OTC pharmacokinetics and treatment of artificial Vibrio anguillarum infection was evaluated in juvenile yellowtail Seriola quinqueradiata followed by serum OTC concentration analysis. When 25 mg kg-1 body weight (BW) OTC was administered in combination with 1250 mg kg-1 BW citric acid, the serum OTC concentration reached almost the same concentration as that of the group treated with 50 mg kg-1 BW OTC. This coadministration successfully suppressed mortality due to vibriosis similar to the group treated with 50 mg kg-1 BW OTC. Conversely, poor efficacy was observed when only 25 mg kg-1 BW OTC was administered. These results suggest that coadministration of citric acid can be beneficial in reducing the dose of OTC needed for effective treatment, and thus contributes to the goal of reduced use of this antibiotic in aquaculture.

EFFECT OF SERUM GONADOTROPHIN ON DEHYDROGENASES OF THE CITRIC ACID CYCLE IN THE OVARY OF THE RAT

1963 ◽  
Vol 42 (4) ◽  
pp. 480-484 ◽  
Author(s):  
B. Eckstein ◽  
R. Landsberg
Keyword(s):  
Citric Acid ◽  
Citric Acid Cycle ◽  
Age Groups ◽  
Succinic Dehydrogenase ◽  
Immature Rat ◽  
Acid Cycle ◽  
Immature Rats ◽  
Rat Ovary

ABSTRACT The succinic, malic and isocitric dehydrogenases in the ovary of immature and mature, normal and serum gonadotrophin injected rats were examined. The Qo2 of these enzymes were markedly enhanced in the gonadotrophin injected rats of both age groups, except in the case of succinic dehydrogenase in the ovary of the immature rats, where a slight non-significant decrease was noted. It is concluded that in the mature rat ovary, gonadotrophin administration stimulates the activity of all the examined dehydrogenases of the citric acid cycle, whereas in the immature rat ovary, at least the isocitric- and malic dehydrogenases are thus stimulated.

Early development of bovine embryos depends on the cooperative action between oxidative and endoplasmic reticulum stresses

2014 ◽  
Author(s):  
Seung-Bin Yoon ◽  
Hae-Jun Yang ◽  
Seong-Eun Mun ◽  
Pil-Soo Jeong ◽  
Seon-A Choi ◽  
...  
Keyword(s):  
Endoplasmic Reticulum ◽  
Early Development ◽  
Bovine Embryos ◽  
Cooperative Action
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