Preparation of Cu(II)-chelated poly(vinyl alcohol) nanofibrous membranes for catalase immobilization

2011 ◽  
Vol 120 (6) ◽  
pp. 3291-3296 ◽  
Author(s):  
Quan Feng ◽  
Xin Xia ◽  
Anfang Wei ◽  
Xueqian Wang ◽  
Qufu Wei ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Nanofibrous Membranes

scholarly journals Electrospun Chitosan/Poly (Vinyl Alcohol)/Graphene Oxide Nanofibrous Membrane with Ciprofloxacin Antibiotic Drug for Potential WoundDressing Application

2019 ◽  
Vol 20 (18) ◽  
pp. 4395 ◽  
Author(s):  
Yang ◽  
Zhang ◽  
Zhang
Keyword(s):  
Graphene Oxide ◽  
Drug Release ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Burst Release ◽  
Drug Release Profile ◽  
Electrospinning Technique ◽  
Antibiotic Drugs ◽  
Antibiotic Drug ◽  
Nanofibrous Membranes

In this paper, nanofibrous membranes based on chitosan (CS), poly (vinyl alcohol) (PVA) and graphene oxide (GO) composites, loaded with antibiotic drugs, such as Ciprofloxacin (Cip) and Ciprofloxacin hydrochloride (CipHcl) were prepared via the electrospinning technique. The uniform and defect-free CS/PVA nanofibers were obtained and GO nanosheets, shaping spindle and spherical, were partially embedded into nanofibers. Besides, the antibiotic drugs were effectively loaded into the nanofibers and part of which were absorbed into GO nanosheets. Intriguingly, the release of the drug absorbed in GO nanosheets regulated the drug release profile trend, avoiding the “burst” release of drug at the release initial stage, and the addition of GO slightly improved the drug release ratio. Nanofibrous membranes showed the significantly enhanced antibacterial activity against Escherichia coli, Staphylococcus aureus and Bacillus subtilis after the addition of antibiotic drug. Moreover, the drug-loaded nanofibrous membranes exhibited excellent cytocompatibility with Melanoma cells, indicative to the great potential potential for applications in wound dressing.

High performance filtration nanofibrous membranes based on hydrophilic poly(vinyl alcohol-co-ethylene) copolymer

Desalination ◽  
2013 ◽  
Vol 329 ◽  
pp. 50-56 ◽  
Author(s):  
Mufang Li ◽  
Xiao Xue ◽  
Dong Wang ◽  
Ying Lu ◽  
Zhihong Wu ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
High Performance ◽  
Poly Vinyl Alcohol ◽  
Ethylene Copolymer ◽  
Nanofibrous Membranes

Characterization of the Properties of Electrospun Blended Hybrid Poly(Vinyl Alcohol)_Aloe Vera/Chitosan Nano-Emulsion Nanofibrous Membranes

2018 ◽  
Vol 792 ◽  
pp. 74-79 ◽  
Author(s):  
Harini Sosiati ◽  
Wahyu Nur Fatihah ◽  
Yusmaniar ◽  
M. Budi Nur Rahman
Keyword(s):  
Tensile Strength ◽  
Vinyl Alcohol ◽  
Tensile Modulus ◽  
Poly Vinyl Alcohol ◽  
Collector Plate ◽  
Fiber Properties ◽  
Fiber Size ◽  
Electrospun Membranes ◽  
Nanofibrous Membranes ◽  
Nano Emulsion

The spinning solution of blended hybrid poly (vinyl alcohol) (PVA)_Aloe Vera (AV) with various concentrations (0%, 3%, 10% and 15%) of chitosan nanoemulsion (CSNe) were electrospun under optimized conditions of high DC voltage 15 kV, distance of spinneret tip to collector plate 16.5 mm and spinneret diameter 0.8 mm. This work aims to manufacture the blended hybrid PVA_AV/CSNe nanofibrous membranes and characterize the solution and fiber properties, and tensile properties of the nanofibrous membranes by varying CSNe concentrations. Scanning electron microscopy (SEM) results revealed that beads-free fiber structure featured in all electrospun membranes with relatively homogeneous fiber size distribution. An increase of CSNe concentration from 0% to 15% reduces the average fiber size from 366 nm to 180 nm and increase tensile strength from 2,52  0.54 MPa to 6.18  0.15 MPa and tensile modulus from 7.5  1.06 MPa to 21.9  9.88 MPa of the membranes, respectively. The tensile strength of the present blended hybrid PVA_AV/CSNE nanofibrous membranes with 15% CSNe concentration and tensile modulus of that with all CSNe concentrations are included in the range of the natural skin properties: i.e. (5.00 – 30.00 MPa) and (4.6 – 20.0 MPa) for tensile strength and modulus, respectively. Such data suggest the potential use of the membranes as wound dressing material in the near future.

Electrospun poly(vinyl alcohol) nanofibrous membranes containing Coptidis Rhizoma extracts for potential biomedical applications

2018 ◽  
Vol 89 (17) ◽  
pp. 3506-3518 ◽  
Author(s):  
Jin Jeong ◽  
Seungsin Lee
Keyword(s):  
Antibacterial Activity ◽  
Vinyl Alcohol ◽  
Drug Carrier ◽  
Drug Loading ◽  
Antibacterial Properties ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Antibacterial Activity ◽  
Coptidis Rhizoma ◽  
Nanofibrous Membranes

Coptidis Rhizoma is a medicinal plant that is well known for its high antibacterial activity against various pathogens and its anti-inflammatory, antioxidant, and hemostatic effects. Here, nanofibrous membranes containing 10, 20, and 30 wt% of Coptidis Rhizoma extracts were fabricated by electrospinning using poly(vinyl alcohol) as the drug carrier and thermally treated to increase their aqueous stability. The antibacterial properties and release characteristics of Coptidis Rhizoma nanofibrous membranes were investigated. Coptidis Rhizoma-loaded nanocomposite fibers exhibited a high drug-loading efficiency ranging from 92% to 97%. The release profile from the nanofibrous membranes of Coptidis Rhizoma showed an initial fast release followed by a gradual release for 48 h. High antibacterial activity of the Coptidis Rhizoma-loaded nanofibrous membranes was exhibited against both Staphylococcus aureus and Staphylococcus epidermidis. These results demonstrate that poly(vinyl alcohol) nanofibrous membranes containing Coptidis Rhizoma extracts have considerable potential to be effective antimicrobial wound dressings based on natural substances.

Adsorption Characteristics of Triclosan on Chitosan/Poly(vinyl alcohol) Composite Nanofibrous Membranes

2013 ◽  
Vol 448-453 ◽  
pp. 134-138
Author(s):  
Si Jia Liu ◽  
Ran Xu
Keyword(s):  
Adsorption Capacity ◽  
Vinyl Alcohol ◽  
Contact Time ◽  
Removal Rate ◽  
Poly Vinyl Alcohol ◽  
Order Model ◽  
Langmuir Isotherm Model ◽  
Pseudo Second Order ◽  
Equilibrium Adsorption Capacity ◽  
Nanofibrous Membranes

Chitosan/Poly (vinyl alcohol) (CS/PVA) composite nanofibrous membranes with diameter between 150-350 nm have been fabricated by electrospinning. The effect of contact time, temperature, pH and concentration of triclosan on the adsorption capacity of the membranes were investigated. The equilibrium adsorption capacity of triclosan on CS/PVA nanofibrous membranes was 61.61 mg/g. The favorable pH for triclosan adsorption was pH 6. After five regeneration cycles, the removal rate of triclosan maintained above 67%. The adsorption of triclosan on the membranes fitted both Freundlich and Langmuir isotherm model. Its adsorption kinetics followed a pseudo-second-order model.

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