Utilizing 2‐phenylpropanal as coupling partner for C‐S bond formation via sequential thioarylation and decarbonylation process: A novel strategy for the synthesis of aryl alkyl sulfides

2019 ◽  
Vol 33 (11) ◽  
Author(s):  
Elham Shaikhi Shahidzadeh ◽  
Najmeh Nowrouzi ◽  
Mohammad Abbasi
Keyword(s):  
Bond Formation ◽  
Novel Strategy ◽  
Coupling Partner

Hybrid nanomaterials for asymmetric purposes: green enantioselective C–C bond formation by chiralization and multi-functionalization approaches

2020 ◽  
Vol 10 (24) ◽  
pp. 8240-8253 ◽  
Author(s):  
Sayed Ali Akbar Razavi ◽  
Kayhaneh Berijani ◽  
Ali Morsali
Keyword(s):  
Bond Formation ◽  
Hybrid Nanomaterials ◽  
Hybrid Nanomaterial ◽  
Novel Strategy

We present a simple and novel strategy for synthesis of a MOF-based chiral multi-functional hybrid nanomaterial through chiralization and multi-functionalization approaches for asymmetric purposes.

ChemInform Abstract: Copper Catalyzed C-N Bond Formation via a Sequential Acylation and Deacylation Process: A Novel Strategy for the Synthesis of Benzanilides.

ChemInform ◽  
2015 ◽  
Vol 46 (26) ◽  
pp. no-no
Author(s):  
Saurabh Kumar ◽  
Rajeshwer Vanjari ◽  
Tirumaleswararao Guntreddi ◽  
Krishna Nand Singh
Keyword(s):  
Bond Formation ◽  
Novel Strategy

scholarly journals Modular radical cross-coupling with sulfones enables access to sp3-rich (fluoro)alkylated scaffolds

Science ◽  
2018 ◽  
Vol 360 (6384) ◽  
pp. 75-80 ◽  
Author(s):  
Rohan R. Merchant ◽  
Jacob T. Edwards ◽  
Tian Qin ◽  
Monika M. Kruszyk ◽  
Cheng Bi ◽  
...  
Keyword(s):  
Bond Formation ◽  
Cross Coupling ◽  
Functional Materials ◽  
Single Electron ◽  
Carbon Bond ◽  
Carbon Carbon Bond ◽  
Coupling Partner

Cross-coupling chemistry is widely applied to carbon-carbon bond formation in the synthesis of medicines, agrochemicals, and other functional materials. Recently, single-electron–induced variants of this reaction class have proven particularly useful in the formation of C(sp2)–C(sp3) linkages, although certain compound classes have remained a challenge. Here, we report the use of sulfones to activate the alkyl coupling partner in nickel-catalyzed radical cross-coupling with aryl zinc reagents. This method’s tolerance of fluoroalkyl substituents proved particularly advantageous for the streamlined preparation of pharmaceutically oriented fluorinated scaffolds that previously required multiple steps, toxic reagents, and nonmodular retrosynthetic blueprints. Five specific sulfone reagents facilitate the rapid assembly of a vast set of compounds, many of which contain challenging fluorination patterns.

Copper catalysed C–N bond formation via a sequential acylation and deacylation process: a novel strategy for the synthesis of benzanilides

RSC Advances ◽  
2015 ◽  
Vol 5 (13) ◽  
pp. 9920-9924 ◽  
Author(s):  
Saurabh Kumar ◽  
Rajeshwer Vanjari ◽  
Tirumaleswararao Guntreddi ◽  
Krishna Nand Singh
Keyword(s):  
Bond Formation ◽  
Copper Catalysis ◽  
Novel Strategy ◽  
Oxidative Amidation

An efficient oxidative amidation of aldehydes using acetanilides as amine component has been developed by copper catalysis. The approach is versatile and proceeds through sequential acylation and deacylation to afford benzanilides.

scholarly journals Iodine-mediated C–N and N–N bond formation: a facile one-pot synthetic approach to 1,2,3-triazoles under metal-free and azide-free conditions

RSC Advances ◽  
2019 ◽  
Vol 9 (46) ◽  
pp. 27021-27031 ◽  
Author(s):  
Geeta Sai Mani ◽  
Kavitha Donthiboina ◽  
Siddiq Pasha Shaik ◽  
Nagula Shankaraiah ◽  
Ahmed Kamal
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Synthetic Approach ◽  
One Pot ◽  
Metal Free ◽  
Novel Strategy

A novel strategy towards the synthesis of 1,4-disubstituted 1,2,3-triazoles via C–N and N–N bond formation has been demonstrated under transition metal-free and azide-free conditions.

Transition-metal-free oxidative carboazidation of acrylamides via cascade C–N and C–C bond-forming reactions

2014 ◽  
Vol 12 (25) ◽  
pp. 4329-4334 ◽  
Author(s):  
Jun Qiu ◽  
Ronghua Zhang
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Efficient Method ◽  
Bond Formation ◽  
Cascade Process ◽  
Metal Free ◽  
Bond Forming ◽  
Bond Forming Reactions ◽  
Radical Cascade ◽  
Novel Strategy

A novel transition-metal-free oxidative carboazidation of acrylamides using inexpensive NaN3 and K2S2O8 was achieved, which not only provided an efficient method to prepare various N3-substituted oxindoles, but also represented a novel strategy for C–N and C–C bond formation via a free-radical cascade process.

Transition-metal-free halocarbocyclisation of acrylamides using K2S2O8

2017 ◽  
Vol 41 (6) ◽  
pp. 352-357 ◽  
Author(s):  
Haiwei Ye ◽  
Liping Zhou ◽  
Yunhua Chen ◽  
Jun Qiu
Keyword(s):  
Transition Metal ◽  
Bond Formation ◽  
Direct Transition ◽  
Metal Free ◽  
Novel Strategy

A novel and direct transition-metal-free oxidative halocarbocyclisation of acrylamides using inexpensive KX (X = I, Br, Cl) and K2S2O8 has been developed. This methodology not only provides an efficient way to construct valuable halogenated oxindoles in good to excellent yields, but also represents a novel strategy for C–X and C–C bond formation.

Sign in / Sign up

Export Citation Format

Share Document