Isatin-SO3H coated on amino propyl modified magnetic nanoparticles (Fe3O4@APTES@isatin-SO3H) as a recyclable magnetic nanoparticle for the simple and rapid synthesis of pyrano[2,3-d] pyrimidines derivatives

2018 ◽  
Vol 33 (1) ◽  
pp. e4602 ◽  
Author(s):  
Sami Sajjadifar ◽  
Zohreh Gheisarzadeh
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Rapid Synthesis ◽  
Modified Magnetic Nanoparticles ◽  
Magnetic Nanoparticles Fe3o4

Thermo-responsive adsorption and separation of amino acid enantiomers using smart polymer-brush-modified magnetic nanoparticles

2016 ◽  
Vol 40 (4) ◽  
pp. 3194-3207 ◽  
Author(s):  
Ya-Ya Song ◽  
Xiao-Dong Song ◽  
Heng Yuan ◽  
Chang-Jing Cheng
Keyword(s):  
Amino Acid ◽  
Magnetic Nanoparticles ◽  
Chiral Recognition ◽  
Magnetic Nanoparticle ◽  
Polymer Brush ◽  
Smart Polymer ◽  
Amino Acid Enantiomers ◽  
Modified Magnetic Nanoparticles ◽  
Recognition Capability

A novel type of multifunctional magnetic nanoparticle with highly chiral recognition capability, excellent thermo-sensitive adsorption and decomplexation properties toward amino acid enantiomers, and recyclability was developed in this study.

Magnetic Nanoparticle–Polyelectrolyte Interaction: A Layered Approach for Biomedical Applications

2008 ◽  
Vol 8 (8) ◽  
pp. 4033-4040 ◽  
Author(s):  
John E. Wong ◽  
Akhilesh K. Gaharwar ◽  
Detlef Müller-Schulte ◽  
Dhirendra Bahadur ◽  
Walter Richtering
Keyword(s):  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Layer By Layer ◽  
Layer Deposition ◽  
Dimethylammonium Chloride ◽  
Modified Magnetic Nanoparticles ◽  
Post Modification ◽  
Nanoparticle Core ◽  
Modification Of The Surface

This study describes the surface modification of magnetic nanoparticles using two different approaches. The first approach consists of an in situ modification of the surface during the precipitation of the magnetic nanoparticles while the second approach consists of a post-modification of the surface after the formation of the magnetic nanoparticles. In the latter case, we adopted the Layer-by-Layer assembly of polyelectrolyte multilayers of poly(diallyl-dimethylammonium) chloride and poly(styrenesulfonate) to build a polymeric shell around the magnetic nanoparticle core, thereby intentionally conferring to this hybrid core–shell the same charge as the charge of the polyelectrolyte deposited in the last layer. Electrophoretic measurements reveal charge reversal indicating successful Layer-by-Layer deposition while magnetization studies show that the superparamagnetic behavior is not much affected by the presence of polyelectrolytes on the modified magnetic nanoparticles. Fourier transform infrared and thermogravimetry analysis results underline that the various polyelectrolytes employed, in both the methodologies adopted, were successfully bound to the nanoparticles.

Rapid and direct MALDI-MS identification of pathogenic bacteria from blood using ionic liquid-modified magnetic nanoparticles (Fe3O4@SiO2)

2014 ◽  
Vol 2 (29) ◽  
pp. 4671-4683 ◽  
Author(s):  
Mukesh L. Bhaisare ◽  
Hani Nasser Abdelhamid ◽  
Bo-Sgum Wu ◽  
Hui-Fen Wu
Keyword(s):  
Ionic Liquid ◽  
Magnetic Nanoparticles ◽  
Pathogenic Bacteria ◽  
Maldi Ms ◽  
Blood Samples ◽  
Bacteria Identification ◽  
Novel Method ◽  
Modified Magnetic Nanoparticles ◽  
Magnetic Nanoparticles Fe3o4

A novel method for pathogenic bacteria identification directly from blood samples using cationic ionic liquid-modified magnetic nanoparticles (CILMS) is reported.

scholarly journals Magnetic Heating of Nanoparticles Applied in the Synthesis of a Magnetically Recyclable Hydrogenation Nanocatalyst

Nanomaterials ◽  
2020 ◽  
Vol 10 (6) ◽  
pp. 1142
Author(s):  
Sašo Gyergyek ◽  
Darja Lisjak ◽  
Miloš Beković ◽  
Miha Grilc ◽  
Blaž Likozar ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Furfuryl Alcohol ◽  
Magnetic Nanoparticle ◽  
Conventional Heating ◽  
Support Material ◽  
Rapid Synthesis ◽  
Rapid Reduction ◽  
Selective Heating ◽  
Magnetic Heating ◽  
Furfural Hydrogenation

Utilization of magnetic nanoparticle-mediated conversion of electromagnetic energy into heat is gaining attention in catalysis as a source of heat needed for a substrate’s chemical reaction (electrification of chemical conversions). We demonstrate that rapid and selective heating of magnetic nanoparticles opens a way to the rapid synthesis of a nanocatalyst. Magnetic heating caused rapid reduction of Ru3+ cations in the vicinity of the support material and enabled preparation of a Ru nanoparticle-bearing nanocatalyst. Comparative synthesis conducted under conventional heating revealed significantly faster Ru3+ reduction under magnetic heating. The faster kinetic was ascribed to the higher surface temperature of the support material caused by rapid magnetic heating. The nanocatalyst was rigorously tested in the hydrotreatment of furfural. The activity, selectivity and stability for furfural hydrogenation to furfuryl alcohol, a valuable biobased monomer, remained high even after four magnetic recycles.

scholarly journals Understanding intracellular nanoparticle trafficking fates through spatiotemporally resolved magnetic nanoparticle recovery

2021 ◽  
Author(s):  
Emily Sheridan ◽  
Silvia Vercellino ◽  
Lorenzo Cursi ◽  
Laurent Adumeau ◽  
James A. Behan ◽  
...  
Keyword(s):  
Decision Making ◽  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Magnetic Extraction

We describe how magnetic nanoparticles can be used to study intracellular nanoparticle trafficking, and how magnetic extraction may be integrated with downstream analyses to investigate nanoscale decision-making events.

scholarly journals Therapeutic Potential of Magnetic Nanoparticle-Based Human Adipose-Derived Stem Cells in a Mouse Model of Parkinson’s Disease

2021 ◽  
Vol 22 (2) ◽  
pp. 654
Author(s):  
Ka Young Kim ◽  
Keun-A Chang
Keyword(s):  
Parkinson’S Disease ◽  
Stem Cells ◽  
Parkinson's Disease ◽  
Magnetic Nanoparticles ◽  
Substantia Nigra ◽  
Mouse Model ◽  
Magnetic Nanoparticle ◽  
Imaging System ◽  
Therapeutic Potential ◽  
Adipose Derived Stem Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra. Several treatments for PD have focused on the management of physical symptoms using dopaminergic agents. However, these treatments induce various adverse effects, including hallucinations and cognitive impairment, owing to non-targeted brain delivery, while alleviating motor symptoms. Furthermore, these therapies are not considered ultimate cures owing to limited brain self-repair and regeneration abilities. In the present study, we aimed to investigate the therapeutic potential of human adipose-derived stem cells (hASCs) using magnetic nanoparticles in a 6-hydroxydopamine (6-OHDA)-induced PD mouse model. We used the Maestro imaging system and magnetic resonance imaging (MRI) for in vivo tracking after transplantation of magnetic nanoparticle-loaded hASCs to the PD mouse model. The Maestro imaging system revealed strong hASCs signals in the brains of PD model mice. In particular, MRI revealed hASCs distribution in the substantia nigra of hASCs-injected PD mice. Behavioral evaluations, including apomorphine-induced rotation and rotarod performance, were significantly recovered in hASCs-injected 6-OHDA induced PD mice when compared with saline-treated counterparts. Herein, we investigated whether hASCs transplantation using magnetic nanoparticles recovered motor functions through targeted brain distribution in a 6-OHDA induced PD mice. These results indicate that magnetic nanoparticle-based hASCs transplantation could be a potential therapeutic strategy in PD.

Simulated Clustering Dynamics of Colloidal Magnetic Nanoparticles

Nanoscale ◽  
2021 ◽  
Author(s):  
Frederik Laust Durhuus ◽  
Lau Halkier Wandall ◽  
Mathias Hoeg Boisen ◽  
Mathias Kure ◽  
Marco Beleggia ◽  
...  
Keyword(s):  
Magnetic Nanoparticles ◽  
Self Assembly ◽  
Biomedical Applications ◽  
Magnetic Nanoparticle ◽  
Bottom Up ◽  
Novel Materials ◽  
Nanoparticle Clusters ◽  
Clustering Dynamics

Magnetically guided self-assembly of nanoparticles is a promising bottom-up method to fabricate novel materials and superstructures, such as, for example, magnetic nanoparticle clusters for biomedical applications. The existence of assembled...

scholarly journals Transient cell stiffening triggered by magnetic nanoparticle exposure

2021 ◽  
Vol 19 (1) ◽  
Author(s):  
Jose E. Perez ◽  
Florian Fage ◽  
David Pereira ◽  
Ali Abou-Hassan ◽  
Sophie Asnacios ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Magnetic Nanoparticles ◽  
Magnetic Nanoparticle ◽  
Early Time ◽  
Population Level ◽  
Short Time Scale ◽  
Initial Contact ◽  
Almost All ◽  
The Impact ◽  
Stiffening Effect

Abstract Background The interactions between nanoparticles and the biological environment have long been studied, with toxicological assays being the most common experimental route. In parallel, recent growing evidence has brought into light the important role that cell mechanics play in numerous cell biological processes. However, despite the prevalence of nanotechnology applications in biology, and in particular the increased use of magnetic nanoparticles for cell therapy and imaging, the impact of nanoparticles on the cells’ mechanical properties remains poorly understood. Results Here, we used a parallel plate rheometer to measure the impact of magnetic nanoparticles on the viscoelastic modulus G*(f) of individual cells. We show how the active uptake of nanoparticles translates into cell stiffening in a short time scale (< 30 min), at the single cell level. The cell stiffening effect is however less marked at the cell population level, when the cells are pre-labeled under a longer incubation time (2 h) with nanoparticles. 24 h later, the stiffening effect is no more present. Imaging of the nanoparticle uptake reveals almost immediate (within minutes) nanoparticle aggregation at the cell membrane, triggering early endocytosis, whereas nanoparticles are almost all confined in late or lysosomal endosomes after 2 h of uptake. Remarkably, this correlates well with the imaging of the actin cytoskeleton, with actin bundling being highly prevalent at early time points into the exposure to the nanoparticles, an effect that renormalizes after longer periods. Conclusions Overall, this work evidences that magnetic nanoparticle internalization, coupled to cytoskeleton remodeling, contributes to a change in the cell mechanical properties within minutes of their initial contact, leading to an increase in cell rigidity. This effect appears to be transient, reduced after hours and disappearing 24 h after the internalization has taken place.

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