scholarly journals Complementing Pyridine‐2,6‐bis(oxazoline) with Cyclometalated N‐Heterocyclic Carbene for Asymmetric Ruthenium Catalysis

2020 ◽  
Vol 59 (30) ◽  
pp. 12392-12395 ◽  
Author(s):  
Long Li ◽  
Feng Han ◽  
Xin Nie ◽  
Yubiao Hong ◽  
Sergei Ivlev ◽  
...  
Keyword(s):  
Ruthenium Catalysis

Remote C–H Functionalizations by Ruthenium Catalysis

Synthesis ◽  
2021 ◽  
Author(s):  
Korkit Korvorapun ◽  
Ramesh C. Samanta ◽  
Torben Rogge ◽  
Lutz Ackermann
Keyword(s):  
Steric Hindrance ◽  
Late Stage ◽  
Crop Protection ◽  
Full Control ◽  
Site Selectivity ◽  
Important Approach ◽  
Distinct Character ◽  
Ruthenium Catalysis ◽  
Material Sciences ◽  
Site Selective

Synthetic transformations of otherwise inert C–H bonds have emerged as a powerful tool for molecular modifications during the last decades, with broad applications towards pharmaceuticals, material sciences and crop protection. Consistently, a key challenge in C–H activation chemistry is the full control of site-selectivity. In addition to substrate control through steric hindrance or kinetic acidity of C–H bonds, one important approach for the site-selective C–H transformation of arenes is the use of chelation-assistance through directing groups, therefore leading to proximity-induced ortho-C–H metalation. In contrast, more challenging remote C–H activations at the meta- or para-positions continue to be scarce. Within this review, we demonstrate the distinct character of ruthenium catalysis for remote C–H activations until March 2021, highlighting among others late-stage modifications of bio-relevant molecules. Moreover, we highlight important mechanistic insights by experiments and computation, highlighting the key importance of carboxylate-assisted C–H activation with ruthenium(II) complexes.

Synthesis of new terpene derivatives via ruthenium catalysis: rearrangement of silylated enynes derived from terpenoids

Tetrahedron ◽  
2003 ◽  
Vol 59 (47) ◽  
pp. 9425-9432 ◽  
Author(s):  
Jérôme Le Nôtre ◽  
Ana Acosta Martinez ◽  
Pierre H Dixneuf ◽  
Christian Bruneau
Keyword(s):  
Ruthenium Catalysis ◽  
Terpene Derivatives

scholarly journals Bio- and air-tolerant carbon–carbon bond formations via organometallic ruthenium catalysis

2009 ◽  
Vol 74 (7-8) ◽  
pp. 1023-1034 ◽  
Author(s):  
Louis Adriaenssens ◽  
Lukáš Severa ◽  
Jan Vávra ◽  
Tereza Šálová ◽  
Jakub Hývl ◽  
...  
Keyword(s):  
Organometallic Compound ◽  
Bond Formation ◽  
Diazo Compound ◽  
Carbon Bond ◽  
Cell Lysate ◽  
Bodily Fluids ◽  
Carbon Carbon Bond ◽  
Ruthenium Catalysis ◽  
Aqueous Conditions ◽  
Alkyne Coupling

Selected [2+2+2] cycloadditions, alkene–alkyne coupling and fusion of enyne with diazo compound, all triggered by an artificial organometallic ruthenium catalyst are demonstrated to proceed under ambient aerobic aqueous conditions in presence of bodily fluids or cell lysate. To the best of our knowledge, these are the first examples of bio- and air-tolerant C–C bond formation catalyzed by an artificial organometallic compound.

scholarly journals Ruthenium catalysis in organic synthesis

2002 ◽  
Vol 74 (1) ◽  
pp. 19-24 ◽  
Author(s):  
Shun-Ichi Murahashi ◽  
Hikaru Takaya ◽  
Takeshi Naota
Keyword(s):  
Organic Synthesis ◽  
Lewis Acid ◽  
Catalytic Reactions ◽  
Biologically Active ◽  
Hydride Complexes ◽  
Base Catalysts ◽  
Acid And Base ◽  
Ruthenium Catalysis ◽  
Lewis Acid And Base ◽  
Neutral Conditions

Ruthenium, rhodium, iridium, and rhenium hydride complexes are highly useful redox Lewis acid and base catalysts. Various substrates bearing hetero atoms are activated by these catalysts and undergo reactions with either nucleophiles or electrophiles under neutral conditions. These types of catalytic reactions are described together with their application to the preparation of various biologically active compounds.

ChemInform Abstract: Direct Allylation of Aromatic and α,β-Unsaturated Carboxamides under Ruthenium Catalysis.

ChemInform ◽  
2015 ◽  
Vol 46 (8) ◽  
pp. no-no
Author(s):  
Mirim Kim ◽  
Satyasheel Sharma ◽  
Neeraj Kumar Mishra ◽  
Sangil Han ◽  
Jihye Park ◽  
...  
Keyword(s):  
Ruthenium Catalysis

One-Pot Ring-Closing Metathesis/1,3-Dipolar Cycloaddition through Assisted Tandem Ruthenium Catalysis: Synthesis of a Dye with Isoindolo[2,1-a]quinoline Structure

2012 ◽  
Vol 125 (3) ◽  
pp. 1037-1041 ◽  
Author(s):  
Mitsuhiro Arisawa ◽  
Yuki Fujii ◽  
Hiroshige Kato ◽  
Hayato Fukuda ◽  
Takashi Matsumoto ◽  
...  
Keyword(s):  
Dipolar Cycloaddition ◽  
Ring Closing Metathesis ◽  
One Pot ◽  
Ruthenium Catalysis

scholarly journals Synthesis of the aglycon of scorzodihydrostilbenes B and D

2019 ◽  
Vol 15 ◽  
pp. 610-616
Author(s):  
Katja Weimann ◽  
Manfred Braun
Keyword(s):  
Antioxidative Agents ◽  
Ruthenium Catalysis

Benzyl- and methyl-protected 2,4-dihydroxyacetophenones are added under ruthenium catalysis to 4-methoxy- and 3,4-dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes are obtained that feature the skeleton of scorzodihydrostilbenes – antioxidative agents that were recently isolated from Scorzonera radiata. Selective deprotection liberates the corresponding phenols, among them the aglycon of scorzodihydrostilbenes B and D.

scholarly journals Regiodivergent C−H and Decarboxylative C−C Alkylation by Ruthenium Catalysis: ortho versus meta Position‐Selectivity

2020 ◽  
Vol 59 (42) ◽  
pp. 18795-18803 ◽  
Author(s):  
Korkit Korvorapun ◽  
Marc Moselage ◽  
Julia Struwe ◽  
Torben Rogge ◽  
Antonis M. Messinis ◽  
...  
Keyword(s):  
Meta Position ◽  
Ruthenium Catalysis
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