Bioinspired Engineering of a Multivalent Aptamer‐Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells

2019 ◽  
Vol 58 (8) ◽  
pp. 2236-2240 ◽  
Author(s):  
Yanling Song ◽  
Yuanzhi Shi ◽  
Mengjiao Huang ◽  
Wei Wang ◽  
Yang Wang ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Capture And Release

Biomimetic recognition strategy for efficient capture and release of circulating tumor cells

2021 ◽  
Vol 188 (6) ◽  
Author(s):  
Ji Zheng ◽  
Dayong Li ◽  
Jin Jiao ◽  
Chengjie Duan ◽  
Youjing Gong ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Capture And Release

Folic Acid-Functionalized Hybrid Photonic Barcodes for Capture and Release of Circulating Tumor Cells

2018 ◽  
Vol 10 (25) ◽  
pp. 21206-21212 ◽  
Author(s):  
Chengxin Luan ◽  
Huan Wang ◽  
Qi Han ◽  
Xiaoyan Ma ◽  
Dagan Zhang ◽  
...  
Keyword(s):  
Folic Acid ◽  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Capture And Release

scholarly journals Photoresponsive immunomagnetic nanocarrier for capture and release of rare circulating tumor cells

2015 ◽  
Vol 6 (11) ◽  
pp. 6432-6438 ◽  
Author(s):  
Song-Wei Lv ◽  
Jing Wang ◽  
Min Xie ◽  
Ning-Ning Lu ◽  
Zhen Li ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Release System ◽  
System P ◽  
Capture And Release

7-Aminocoumarin compound was synthesized and used as phototrigger to cage EpCAM-antibody to construct a photocontrolled CTCs capture and release system.

Magnetic particles assisted capture and release of rare circulating tumor cells using wavy-herringbone structured microfluidic devices

Lab on a Chip ◽  
2017 ◽  
Vol 17 (19) ◽  
pp. 3291-3299 ◽  
Author(s):  
Wentao Shi ◽  
Shunqiang Wang ◽  
Ahmad Maarouf ◽  
Christopher G. Uhl ◽  
Ran He ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Magnetic Particles ◽  
Microfluidic Devices ◽  
Rare Tumor ◽  
Capture And Release

Wavy-herringbone structured microfluidic devices promote capture and collection of rare tumor cells assisted by magnetic particles.

Nanotopographic Biomaterials for Isolation of Circulating Tumor Cells

2014 ◽  
Vol 5 (4) ◽  
Author(s):  
Weiyi Qian ◽  
Yan Zhang ◽  
Andrew Gordon ◽  
Weiqiang Chen
Keyword(s):  
Tumor Cells ◽  
Circulating Tumor Cells ◽  
Cancer Diagnosis ◽  
Cancer Metastasis ◽  
Early Cancer ◽  
Tumor Mass ◽  
Early Cancer Diagnosis ◽  
Capture And Release ◽  
Increasing Demand ◽  
Detection Technologies

Circulating tumor cells (CTCs) shed from the primary tumor mass and circulating in the bloodstream of patients are believed to be vital to understand of cancer metastasis and progression. Capture and release of CTCs for further enumeration and molecular characterization holds the key for early cancer diagnosis, prognosis and therapy evaluation. However, detection of CTCs is challenging due to their rarity, heterogeneity and the increasing demand of viable CTCs for downstream biological analysis. Nanotopographic biomaterial-based microfluidic systems are emerging as promising tools for CTC capture with improved capture efficiency, purity, throughput and retrieval of viable CTCs. This review offers a brief overview of the recent advances in this field, including CTC detection technologies based on nanotopographic biomaterials and relevant nanofabrication methods. Additionally, the possible intracellular mechanisms of the intrinsic nanotopography sensitive responses that lead to the enhanced CTC capture are explored.

Sign in / Sign up

Export Citation Format

Share Document