scholarly journals Palladium-Catalyzed Atom-Transfer Radical Cyclization at Remote Unactivated C(sp3 )−H Sites: Hydrogen-Atom Transfer of Hybrid Vinyl Palladium Radical Intermediates

2018 ◽  
Vol 57 (10) ◽  
pp. 2712-2715 ◽  
Author(s):  
Maxim Ratushnyy ◽  
Marvin Parasram ◽  
Yang Wang ◽  
Vladimir Gevorgyan
Keyword(s):  
Hydrogen Atom ◽  
Hydrogen Atom Transfer ◽  
Radical Cyclization ◽  
Atom Transfer ◽  
Radical Intermediates ◽  
Palladium Catalyzed ◽  
Atom Transfer Radical Cyclization

Sulfamides Direct Radical-Mediated Chlorination of Aliphatic C–H Bonds

2019 ◽  
Author(s):  
Melanie Short ◽  
Mina Shehata ◽  
Matthew Sanders ◽  
Jennifer Roizen
Keyword(s):  
Hydrogen Atom ◽  
Transfer Reaction ◽  
Hydrogen Atom Transfer ◽  
Chain Propagation ◽  
Propagation Mechanism ◽  
Atom Transfer ◽  
Radical Chain ◽  
Radical Intermediates ◽  
Transfer Processes ◽  
Unusual Position

Sulfamides guide intermolecular chlorine transfer to gamma-C(sp<sup>3</sup>) centers. This unusual position-selectivity arises because accessed sulfamidyl radical intermediates engage in otherwise rare 1,6-hydrogen-atom transfer processes. The disclosed chlorine-transfer reaction relies on a light-initiated radical chain-propagation mechanism to oxidize C(sp<sup>3</sup>)-H bonds.

Sulfamides Direct Radical-Mediated Chlorination of Aliphatic C–H Bonds

2019 ◽  
Author(s):  
Melanie Short ◽  
Mina Shehata ◽  
Matthew Sanders ◽  
Jennifer Roizen
Keyword(s):  
Hydrogen Atom ◽  
Transfer Reaction ◽  
Hydrogen Atom Transfer ◽  
Chain Propagation ◽  
Propagation Mechanism ◽  
Atom Transfer ◽  
Radical Chain ◽  
Radical Intermediates ◽  
Transfer Processes ◽  
Unusual Position

Sulfamides guide intermolecular chlorine transfer to gamma-C(sp<sup>3</sup>) centers. This unusual position-selectivity arises because accessed sulfamidyl radical intermediates engage in otherwise rare 1,6-hydrogen-atom transfer processes. The disclosed chlorine-transfer reaction relies on a light-initiated radical chain-propagation mechanism to oxidize C(sp<sup>3</sup>)-H bonds.

Iron-catalyzed hydrogen atom transfer induced cyclization of 1,6-enynes for the synthesis of ketoximes: a combined experimental and computational study

2021 ◽  
Author(s):  
Mingming Zhao ◽  
Wei He ◽  
Liang-Hua Zou ◽  
Dawei Wang ◽  
Tian-Yu Sun ◽  
...  
Keyword(s):  
Hydrogen Atom ◽  
Computational Study ◽  
Hydrogen Atom Transfer ◽  
Radical Cyclization ◽  
Atom Transfer

An iron-catalyzed reductive radical cyclization/hydro-oximation of 1,6-enynes with tBuONO was developed, leading to functionalized benzofuran, benzothiophene, and cyclopentenyl-based ketoximes.

scholarly journals Concise Total Synthesis of (+)-Aphanorphine

Synlett ◽  
2021 ◽  
Author(s):  
Yukun Guan ◽  
Cheng Wang
Keyword(s):  
Hydrogen Atom ◽  
Total Synthesis ◽  
Hydrogen Atom Transfer ◽  
Radical Cyclization ◽  
Atom Transfer ◽  
Key Features ◽  
Form Ring

AbstractA concise total synthesis of (+)-aphanorphine is described. The key features of the strategy include a Pd-catalyzed intermolecular trimethylenemethane [3+2]-cycloaddition to form ring C and a Co-catalyzed radical cyclization through a hydrogen-atom transfer to close ring B. The synthesis was completed in six steps.

scholarly journals Characterization and Fate of Hydrogen-Bonded Free-Radical Intermediates and Their Coupling Products from the Hydrogen Atom Transfer Agent 1,8-Naphthalenediol

ACS Omega ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 3918-3927 ◽  
Author(s):  
Paola Manini ◽  
Massimo Bietti ◽  
Marco Galeotti ◽  
Michela Salamone ◽  
Osvaldo Lanzalunga ◽  
...  
Keyword(s):  
Free Radical ◽  
Hydrogen Atom ◽  
Hydrogen Atom Transfer ◽  
Atom Transfer ◽  
Radical Intermediates ◽  
Hydrogen Bonded
Sign in / Sign up

Export Citation Format

Share Document