Biosensing by Tandem Reactions of Structure Switching, Nucleolytic Digestion, and DNA Amplification of a DNA Assembly

2015 ◽  
Vol 54 (33) ◽  
pp. 9637-9641 ◽  
Author(s):  
Meng Liu ◽  
Wenqing Zhang ◽  
Qiang Zhang ◽  
John D. Brennan ◽  
Yingfu Li
2015 ◽  
Vol 127 (33) ◽  
pp. 9773-9777 ◽  
Author(s):  
Meng Liu ◽  
Wenqing Zhang ◽  
Qiang Zhang ◽  
John D. Brennan ◽  
Yingfu Li

2017 ◽  
Vol 89 ◽  
pp. 964-969 ◽  
Author(s):  
Junlong Li ◽  
Kexin Sun ◽  
Zhongping Chen ◽  
Jifei Shi ◽  
Dandan Zhou ◽  
...  

2020 ◽  
Vol 2 (10) ◽  
pp. 929-941
Author(s):  
Hong Je Cho ◽  
Bingjun Xu
Keyword(s):  

2020 ◽  
Vol 362 (23) ◽  
pp. 5524-5528
Author(s):  
Mengxue Lu ◽  
Xin Wang ◽  
Zongli Xiong ◽  
Jingxiang Duan ◽  
Wen Ren ◽  
...  

Author(s):  
Jingwen Chen ◽  
Long Qi ◽  
Biying Zhang ◽  
Minda Chen ◽  
Takeshi Kobayashi ◽  
...  

The study of the reaction mechanism and complex network for heterogeneously catalyzed tandem reactions is challenging but can guide reaction design and optimization. Here, we describe using a bifunctional metal-organic...


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kelsey E. Witt ◽  
Karthik Yarlagadda ◽  
Julie M. Allen ◽  
Alyssa C. Bader ◽  
Mary L. Simon ◽  
...  

AbstractPaleofeces or coprolites are often used to reconstruct diet at archaeological sites, usually using macroscopic analyses or targeted DNA amplification and sequencing. Here we present an integrative analysis of dog coprolites, combining macroscopic analyses, stable isotope measurements, and DNA shotgun sequencing to examine diet and health status. Dog coprolites used in this study were recovered from the Janey B. Goode and East Saint Louis archaeological sites, both of which are located in the American Bottom, an extensive Mississippi River floodplain in Southwestern Illinois. Based on the context of recovery, coprolites are assigned to the Late Woodland and Terminal Late Woodland periods (ca. 600–1050 AD). Given the scarcity of human remains from this time period, these dog coprolites can be useful as a proxy for understanding human diet during the Late Woodland period. We find that the Late Woodland dogs consumed a variety of fish as well as bird and plant taxa, possibly including maize, and also harbored intestinal parasites and pathogenic bacteria. By sequencing the fecal microbiome of the coprolites, we find some similarities to modern dog microbiomes, as well as specific taxa that can be used to discriminate between modern and ancient microbiomes, excluding soil contaminants. As dogs are often used as a surrogate to assess human diet, humans living with these dogs likely had a similar diet and were affected by similar parasites. These analyses, when integrated, show a more comprehensive view of ancient dog and human diet and health in the region during the initial expansion of maize agriculture than any individual method could alone.


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