scholarly journals Does Size Really Matter? The Steric Isotope Effect in a Supramolecular Host-Guest Exchange Reaction

2010 ◽  
Vol 49 (21) ◽  
pp. 3635-3637 ◽  
Author(s):  
Jeffrey S. Mugridge ◽  
Robert G. Bergman ◽  
Kenneth N. Raymond
Keyword(s):  
Exchange Reaction ◽  
Isotope Effect

scholarly journals Does Size Really Matter? The Steric Isotope Effect in a Supramolecular Host-Guest Exchange Reaction

2010 ◽  
Vol 122 (21) ◽  
pp. 3717-3719 ◽  
Author(s):  
Jeffrey S. Mugridge ◽  
Robert G. Bergman ◽  
Kenneth N. Raymond
Keyword(s):  
Exchange Reaction ◽  
Isotope Effect

Unequal primary kinetic isotope effects in the base-catalysed H–D exchange of diastereotopic protons

1980 ◽  
Vol 58 (1) ◽  
pp. 72-78 ◽  
Author(s):  
Robert R. Fraser ◽  
Philippe J. Champagne
Keyword(s):  
Transition State ◽  
Exchange Reaction ◽  
Isotope Effect ◽  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Deuterium Isotope Effect ◽  
Kinetic Isotope

Primary kinetic isotope effects have been measured for the base-catalyzed exchange reaction of 4′,1″-dimethyl-1,2,3,4-dibenzcyclohepta-1,3-diene-6-one, 1. It was found that the isotope effects kH/kT and kD/kT for the faster exchanging protons (13.6 and 3.8 respectively) are significantly larger than the corresponding values for the slower exchanging protons (4.6 and 1.6 respectively). These differences could result from truly unequal isotope effects due to transition state differences or intrusion of a second pathway for exchange of the less reactive proton in the dedeuteration reaction. The data appear to support the latter interpretation. The secondary deuterium isotope effect was found to be 1.18.

Innentitelbild: Does Size Really Matter? The Steric Isotope Effect in a Supramolecular Host-Guest Exchange Reaction (Angew. Chem. 21/2010)

2010 ◽  
Vol 122 (21) ◽  
pp. 3626-3626 ◽  
Author(s):  
Jeffrey S. Mugridge ◽  
Robert G. Bergman ◽  
Kenneth N. Raymond
Keyword(s):  
Exchange Reaction ◽  
Isotope Effect

Isotope effect on the location of variational transition states: The hydrogen exchange reaction

1986 ◽  
Vol 18 (9) ◽  
pp. 1079-1086
Author(s):  
Luis Bañares Morcillo ◽  
Angel Gonzalez Ureña ◽  
Michael Menzinger
Keyword(s):  
Exchange Reaction ◽  
Isotope Effect ◽  
Hydrogen Exchange ◽  
Transition States
Sign in / Sign up

Export Citation Format

Share Document