Comment Concerning the Effect on the Diborane-Pentaborane Exchange Reaction of the Reported Deuterium Isotope Effect in the Decomposition of Diborane

1962 ◽  
Vol 1 (4) ◽  
pp. 973-975
Author(s):  
Joyce J. Kaufman
Keyword(s):  
Exchange Reaction ◽  
Isotope Effect ◽  
Deuterium Isotope Effect

Unequal primary kinetic isotope effects in the base-catalysed H–D exchange of diastereotopic protons

1980 ◽  
Vol 58 (1) ◽  
pp. 72-78 ◽  
Author(s):  
Robert R. Fraser ◽  
Philippe J. Champagne
Keyword(s):  
Transition State ◽  
Exchange Reaction ◽  
Isotope Effect ◽  
Isotope Effects ◽  
Kinetic Isotope Effects ◽  
Deuterium Isotope Effect ◽  
Kinetic Isotope

Primary kinetic isotope effects have been measured for the base-catalyzed exchange reaction of 4′,1″-dimethyl-1,2,3,4-dibenzcyclohepta-1,3-diene-6-one, 1. It was found that the isotope effects kH/kT and kD/kT for the faster exchanging protons (13.6 and 3.8 respectively) are significantly larger than the corresponding values for the slower exchanging protons (4.6 and 1.6 respectively). These differences could result from truly unequal isotope effects due to transition state differences or intrusion of a second pathway for exchange of the less reactive proton in the dedeuteration reaction. The data appear to support the latter interpretation. The secondary deuterium isotope effect was found to be 1.18.

Partial kinetic ‘resolution’ resulting from a deuterium isotope effect

1991 ◽  
Vol 0 (12) ◽  
pp. 801-802 ◽  
Author(s):  
Panayiotis Anastasis ◽  
Raymond Duffin ◽  
Christopher Gilmore ◽  
Karl Overton
Keyword(s):  
Isotope Effect ◽  
Kinetic Resolution ◽  
Deuterium Isotope Effect
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