A New Strategy for Solid-Phase Synthesis ofO-Glycopeptides

1992 ◽  
Vol 31 (7) ◽  
pp. 857-859 ◽  
Author(s):  
Tim Bielfeldt ◽  
Stefan Peters ◽  
Morten Meldal ◽  
Klaus Bock ◽  
Hans Paulsen
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
New Strategy

A new strategy for total solid-phase synthesis of polymyxins

2015 ◽  
Vol 56 (33) ◽  
pp. 4796-4799 ◽  
Author(s):  
Wei-Liang Xu ◽  
A-Long Cui ◽  
Xin-Xin Hu ◽  
Xue-Fu You ◽  
Zhuo-Rong Li ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Total Solid ◽  
Phase Synthesis ◽  
New Strategy

Solid-phase synthesis of larger peptides by a new strategy of detachment from the resin

Biopolymers ◽  
1981 ◽  
Vol 20 (9) ◽  
pp. 1833-1843 ◽  
Author(s):  
Ching-I Niu ◽  
Shi-Zhen Yang ◽  
An-Qing Ma ◽  
Yun-Neng Chen ◽  
Yong-Qing Jiang ◽  
...  
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
New Strategy

ChemInform Abstract: A New Strategy for Solid-Phase Synthesis of O-Glycopeptides.

ChemInform ◽  
2010 ◽  
Vol 23 (42) ◽  
pp. no-no
Author(s):  
T. BIELFELDT ◽  
S. PETERS ◽  
M. MELDAL ◽  
K. BOCK ◽  
H. PAULSEN
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
New Strategy

New strategy towards the efficient solid phase synthesis of cyclopeptides

Tetrahedron ◽  
2006 ◽  
Vol 62 (6) ◽  
pp. 1124-1130 ◽  
Author(s):  
Thomas Berthelot ◽  
Mario Gonçalves ◽  
Georges Laïn ◽  
Karine Estieu-Gionnet ◽  
Gérard Déléris
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
New Strategy

scholarly journals Liquid-Phase and Ultrahigh-Frequency-Acoustofluidics-Based Solid-Phase Synthesis of Biotin-Tagged 6′/3′-Sialyl-N-Acetylglucosamine by Sequential One-Pot Multienzyme System

Catalysts ◽  
2020 ◽  
Vol 10 (11) ◽  
pp. 1347
Author(s):  
Mengge Gong ◽  
Tiechuan Li ◽  
Lina Wu ◽  
Zhenxing Zhang ◽  
Lishi Ren ◽  
...  
Keyword(s):  
Magnetic Beads ◽  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Ultrahigh Frequency ◽  
Oligosaccharide Synthesis ◽  
One Pot ◽  
Microfluidic Mixing ◽  
Phase Synthesis ◽  
Multienzyme System ◽  
New Strategy

6′/3′-Sialylated N-acetyllactosamine (6′/3′-SLN) is important for discrimination of the source (human or avian) of influenza virus strains. Biotinylated oligosaccharides have been widely used for analysis and quick detection. The development of efficient strategies to synthesize biotin-tagged 6′/3′-SLN have become necessary. Effective mixing is essential for enzymatic solid-phase oligosaccharide synthesis (SPOS). In the current study, newly developed technology ultrahigh-frequency-acoustofluidics (UHFA), which can provide a powerful source for efficient microfluidic mixing, solid-phase oligosaccharide synthesis and one-pot multienzyme (OPME) system, were used to develop a new strategy for oligosaccharide synthesis. Firstly, biotinylated N-acetylglucosamine was designed and chemically synthesized through traditional approaches. Secondly, biotinylated 6′- and 3′-sialyl-N-acetylglucosamines were prepared in solution through two sequential OPME modules in with a yield of ~95%. Thirdly, 6′-SLN was also prepared through UHFA-based enzymatic solid-phase synthesis on magnetic beads with a yield of 64.4%. The current strategy would be potentially used for synthesis of functional oligosaccharides.

A New Strategy Towards the Efficient Solid-Phase Synthesis of Cyclopeptides

Synfacts ◽  
2006 ◽  
Vol 2006 (6) ◽  
pp. 0621-0621
Author(s):  
G. Déléris ◽  
T. Berthelot ◽  
M. Gonçalves ◽  
G. Laïn ◽  
K. Estieu-Gionnet
Keyword(s):  
Solid Phase Synthesis ◽  
Solid Phase ◽  
Phase Synthesis ◽  
New Strategy
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