scholarly journals Structural Studies Reveal Enantiospecific Recognition of a DNA G‐Quadruplex by a Ruthenium Polypyridyl Complex

2019 ◽  
Vol 131 (29) ◽  
pp. 9986-9990 ◽  
Author(s):  
Kane McQuaid ◽  
Holly Abell ◽  
Sarah P. Gurung ◽  
David R. Allan ◽  
Graeme Winter ◽  
...  
Keyword(s):  
Structural Studies ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
G Quadruplex

scholarly journals Structural Studies Reveal Enantiospecific Recognition of a DNA G‐Quadruplex by a Ruthenium Polypyridyl Complex

2019 ◽  
Vol 58 (29) ◽  
pp. 9881-9885 ◽  
Author(s):  
Kane McQuaid ◽  
Holly Abell ◽  
Sarah P. Gurung ◽  
David R. Allan ◽  
Graeme Winter ◽  
...  
Keyword(s):  
Structural Studies ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
G Quadruplex

Visual specific luminescent probing of hybrid G-quadruplex DNA by a ruthenium polypyridyl complex

2012 ◽  
Vol 48 (87) ◽  
pp. 10781 ◽  
Author(s):  
Guo-Liang Liao ◽  
Xiang Chen ◽  
Liang-Nian Ji ◽  
Hui Chao
Keyword(s):  
Ruthenium Polypyridyl ◽  
Quadruplex Dna ◽  
Polypyridyl Complex ◽  
G Quadruplex

A novel, label-free fluorescent aptasensor for cocaine detection based on a G-quadruplex and ruthenium polypyridyl complex molecular light switch

2016 ◽  
Vol 8 (18) ◽  
pp. 3740-3746 ◽  
Author(s):  
Songbai Zhang ◽  
Linping Wang ◽  
Meiling Liu ◽  
Yanqing Qiu ◽  
Mengna Wang ◽  
...  
Keyword(s):  
High Selectivity ◽  
Label Free ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
G Quadruplex ◽  
Molecular Light Switch ◽  
Cocaine Detection ◽  
Fluorescent Aptasensor

A [Ru(bpy)2(bqdppz)]2+ ligand with high selectivity towards G-quadruplex was synthesized and introduced to serve as a prominent molecular light switch via specifically recognizing the cocaine aptamer-involved G-quadruplex.

A Mixed Ruthenium Polypyridyl Complex Containing a PEG-Bipyridine Macroligand

2004 ◽  
Vol 25 (7) ◽  
pp. 793-798 ◽  
Author(s):  
Veronica Marin ◽  
Elisabeth Holder ◽  
Michael A. R. Meier ◽  
Richard Hoogenboom ◽  
Ulrich S. Schubert
Keyword(s):  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex

scholarly journals Intra-locked G-quadruplex structures formed by irregular DNA G-rich motifs

2020 ◽  
Vol 48 (6) ◽  
pp. 3315-3327 ◽  
Author(s):  
Arijit Maity ◽  
Fernaldo Richtia Winnerdy ◽  
Weili Denyse Chang ◽  
Gang Chen ◽  
Anh Tuân Phan
Keyword(s):  
Human Genome ◽  
Dna Sequences ◽  
Structural Features ◽  
Nmr Structure ◽  
Solution Nmr ◽  
Structural Studies ◽  
High Propensity ◽  
G Quadruplex ◽  
High Prevalence

Abstract G-rich DNA sequences with tracts of three or more continuous guanines (G≥3) are known to have high propensity to adopt stable G-quadruplex (G4) structures. Bioinformatic analyses suggest high prevalence of G-rich sequences with short G-tracts (G≤2) in the human genome. However, due to limited structural studies, the folding principles of such sequences remain largely unexplored and hence poorly understood. Here, we present the solution NMR structure of a sequence named AT26 consisting of irregularly spaced G2 tracts and two isolated single guanines. The structure is a four-layered G4 featuring two bi-layered blocks, locked between themselves in an unprecedented fashion making it a stable scaffold. In addition to edgewise and propeller-type loops, AT26 also harbors two V-shaped loops: a 2-nt V-shaped loop spanning two G-tetrad layers and a 0-nt V-shaped loop spanning three G-tetrad layers, which are named as VS- and VR-loop respectively, based on their distinct structural features. The intra-lock motif can be a basis for extending the G-tetrad core and a very stable intra-locked G4 can be formed by a sequence with G-tracts of various lengths including several G2 tracts. Findings from this study will aid in understanding the folding of G4 topologies from sequences containing irregularly spaced multiple short G-tracts.

scholarly journals Catalytic Water-Oxidation Activity of a Weakly Coupled Binuclear Ruthenium Polypyridyl Complex

2017 ◽  
Vol 2017 (4) ◽  
pp. 768-768 ◽  
Author(s):  
Tiago A. Matias ◽  
Ana P. Mangoni ◽  
Sergio H. Toma ◽  
Francisca N. Rein ◽  
Reginaldo C. Rocha ◽  
...  
Keyword(s):  
Water Oxidation ◽  
Ruthenium Polypyridyl ◽  
Oxidation Activity ◽  
Polypyridyl Complex ◽  
Weakly Coupled

Spectroelectrochemical studies of a ruthenium complex containing the pH sensitive 4,4′-dihydroxy-2,2′-bipyridine ligand

2018 ◽  
Vol 47 (12) ◽  
pp. 4149-4161 ◽  
Author(s):  
Erin J. Viere ◽  
Ashley E. Kuhn ◽  
Margaret H. Roeder ◽  
Nicholas A. Piro ◽  
W. Scott Kassel ◽  
...  
Keyword(s):  
Electronic Properties ◽  
Ruthenium Complex ◽  
Ph Sensitive ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
Structural And Electronic Properties ◽  
Bipyridine Ligand

The effects of oxidation by one electron on the structural and electronic properties of a ruthenium polypyridyl complex with a pH sensitive ligand is detailed.

scholarly journals Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies

2020 ◽  
Vol 59 (11) ◽  
pp. 7710-7720 ◽  
Author(s):  
Anja Busemann ◽  
Can Araman ◽  
Ingrid Flaspohler ◽  
Alessandro Pratesi ◽  
Xue-Quan Zhou ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Ruthenium Polypyridyl ◽  
Polypyridyl Complex ◽  
Interaction Studies
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