scholarly journals Terminal Alkyne Coupling Reactions through a Ring: Mechanistic Insights and Regiochemical Switching

2018 ◽  
Vol 130 (37) ◽  
pp. 12179-12182 ◽  
Author(s):  
Caroline M. Storey ◽  
Matthew R. Gyton ◽  
Rhiann E. Andrew ◽  
Adrian B. Chaplin
Keyword(s):  
Coupling Reactions ◽  
Terminal Alkyne ◽  
Alkyne Coupling

scholarly journals Reactions of Rh(PNP) pincer complexes with terminal alkynes: homocoupling through a ring or not at all

2020 ◽  
Vol 49 (46) ◽  
pp. 16649-16652
Author(s):  
Thomas M. Hood ◽  
Adrian B. Chaplin
Keyword(s):  
Pincer Complexes ◽  
Coupling Reactions ◽  
Terminal Alkynes ◽  
Terminal Alkyne ◽  
Pincer Ligand ◽  
Alkyne Coupling

“Switching on” a metal's capacity to promote terminal alkyne coupling reactions using a macrocyclic pincer ligand.

scholarly journals Terminal Alkyne Coupling Reactions Through a Ring: Effect of Ring Size on Rate and Regioselectivity

2020 ◽  
Vol 26 (64) ◽  
pp. 14715-14723 ◽  
Author(s):  
Caroline M. Storey ◽  
Matthew R. Gyton ◽  
Rhiann E. Andrew ◽  
Adrian B. Chaplin
Keyword(s):  
Ring Size ◽  
Coupling Reactions ◽  
Terminal Alkyne ◽  
Alkyne Coupling ◽  
Ring Effect

scholarly journals Terminal Alkyne Coupling Reactions through a Ring: Mechanistic Insights and Regiochemical Switching

2018 ◽  
Vol 57 (37) ◽  
pp. 12003-12006 ◽  
Author(s):  
Caroline M. Storey ◽  
Matthew R. Gyton ◽  
Rhiann E. Andrew ◽  
Adrian B. Chaplin
Keyword(s):  
Coupling Reactions ◽  
Terminal Alkyne ◽  
Alkyne Coupling

Cross-Coupling Reactions with 2-Amino-/Acetylamino-Substituted 3-Iodo-1,4-naphthoquinones: Convenient Synthesis of Novel Alkenyl- and Alkynylnaphthoquinones and Derivatives

Synthesis ◽  
2021 ◽  
Author(s):  
Felipe C. Demidoff ◽  
Leandro L. de Carvalho ◽  
Eduardo José P. Rodrigues Filho ◽  
Andréa Luzia F. de Souza ◽  
Chaquip D. Netto
Keyword(s):  
Click Chemistry ◽  
Organic Synthesis ◽  
Biological Activities ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Large Array ◽  
Terminal Alkyne ◽  
Co Catalyst ◽  
Cross Coupling Reactions ◽  
Convenient Synthesis

AbstractFunctionalized 1,4-naphthoquinones have been employed as versatile synthons in organic synthesis, in addition to presenting a large array of biological activities. Herein, the applications of 2-amino-/ acetylamino-substituted 3-iodo-1,4-naphthoquinones in cross-coupling reactions are described to successfully afford sixteen novel 3-styryl-1,4-naphthoquinones (amino-stilbene-quinone hybrids) and four 3-alkynyl-1,4-naphthoquinone in overall good yields. Interestingly, the alkynylated derivatives could be obtained from ligand- and Pd-free CuI-mediated cross-coupling reactions, after extensive investigations to exclude Pd as a co-catalyst. Lastly, the desilanized terminal alkyne was subjected to click chemistry reactions to give two novel triazole-1,4-naphthoquinone hybrids.

Alkyne−Alkyne Coupling Reactions with W(CO)(PhC⋮CPh)3and W(NCMe)(PhC⋮CPh)3

1997 ◽  
Vol 16 (12) ◽  
pp. 2698-2708 ◽  
Author(s):  
Wen-Yann Yeh ◽  
Chi-Lin Ho ◽  
Michael Y. Chiang ◽  
I-Ting Chen
Keyword(s):  
Coupling Reactions ◽  
Alkyne Coupling

Regiospecific Palladium-Catalyzed Cross-Coupling Reactions Using the Operational Equivalent of 1,3-Dilithiopropyne

Synthesis ◽  
2020 ◽  
Vol 52 (16) ◽  
pp. 2387-2394 ◽  
Author(s):  
Jorge A. Cabezas ◽  
Natasha Ferllini
Keyword(s):  
Coupling Reaction ◽  
Cross Coupling ◽  
Coupling Reactions ◽  
Terminal Alkyne ◽  
Copper Iodide ◽  
Reaction Conditions ◽  
Cross Coupling Reactions ◽  
Cross Coupling Reaction ◽  
Palladium Catalyzed ◽  
High Yields

A regiospecific palladium-catalyzed cross-coupling reaction using the operational equivalent of the dianion 1,3-dilithiopropyne, with aromatic iodides is reported. This reaction gives high yields of 1-propyn-1-yl-benzenes and 2-(propyn-1-yl)thiophenes in the presence of catalytic amounts of palladium(0) or (II) and stoichiometric amounts of copper iodide. No terminal alkyne or allene isomers were detected. Reaction conditions were very mild and several functional groups were tolerated.

scholarly journals Alkene-Directed, Nickel-Catalyzed Alkyne Coupling Reactions.

ChemInform ◽  
2004 ◽  
Vol 35 (31) ◽  
Author(s):  
Karen M. Miller ◽  
Torsak Luanphaisarnnont ◽  
Carmela Molinaro ◽  
Timothy F. Jamison
Keyword(s):  
Coupling Reactions ◽  
Alkyne Coupling
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