Reactive Oxygen Species-Responsive Protein Modification and Its Intracellular Delivery for Targeted Cancer Therapy

2014 ◽  
Vol 126 (49) ◽  
pp. 13662-13666 ◽  
Author(s):  
Ming Wang ◽  
Shuo Sun ◽  
Caleb I. Neufeld ◽  
Bernardo Perez-Ramirez ◽  
Qiaobing Xu
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Protein Modification ◽  
Reactive Oxygen ◽  
Intracellular Delivery ◽  
Oxygen Species ◽  
Targeted Cancer Therapy

scholarly journals Conducting polymer nanoparticles for targeted cancer therapy

RSC Advances ◽  
2015 ◽  
Vol 5 (47) ◽  
pp. 37943-37956 ◽  
Author(s):  
Mona Doshi ◽  
Marissa Krienke ◽  
Saeid Khederzadeh ◽  
Henry Sanchez ◽  
Alicja Copik ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Conducting Polymer ◽  
Targeted Delivery ◽  
Reactive Oxygen ◽  
Polymer Nanoparticles ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
Fluorescence Bioimaging

Functionalized conducting polymer nanoparticles allow for targeted delivery, tracking by fluorescence bioimaging, and therapeutics through formation of reactive oxygen species.

scholarly journals Integration of intracellular telomerase monitoring by electrochemiluminescence technology and targeted cancer therapy by reactive oxygen species

2017 ◽  
Vol 8 (12) ◽  
pp. 8025-8029 ◽  
Author(s):  
Huairong Zhang ◽  
Binxiao Li ◽  
Zhaomei Sun ◽  
Hong Zhou ◽  
Shusheng Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Cancer Therapy ◽  
Cancer Cells ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Targeted Cancer Therapy ◽  
High Efficacy

ROS and polyluminol–Pt NPs were used for intracellular telomerase detection and to induce apoptosis in HL-60 cancer cells with high efficacy.

A glucose-depleting silica nanosystem for increasing reactive oxygen species and scavenging glutathione in cancer therapy

2019 ◽  
Vol 55 (89) ◽  
pp. 13374-13377 ◽  
Author(s):  
Wee Kong Ong ◽  
Deblin Jana ◽  
Yanli Zhao
Keyword(s):  
Reactive Oxygen Species ◽  
Hydrogen Peroxide ◽  
Cancer Therapy ◽  
Reactive Oxygen ◽  
Species Level ◽  
Reactive Oxygen Species Level ◽  
Oxygen Species ◽  
Anticancer Treatment ◽  
Intracellular Glucose

A novel silica nanosystem is fabricated to convert intracellular glucose to hydrogen peroxide for enhancing reactive oxygen species level and triggering p-quinomethane release to scavenge glutathione, achieving synergistic anticancer treatment.

scholarly journals Ultrasound-induced reactive oxygen species generation and mitochondria-specific damage by sonodynamic agent/metal ion-doped mesoporous silica

RSC Advances ◽  
2019 ◽  
Vol 9 (68) ◽  
pp. 39924-39931 ◽  
Author(s):  
Kecan Lin ◽  
Ziguo Lin ◽  
Yujie Li ◽  
Youshi Zheng ◽  
Da Zhang
Keyword(s):  
Reactive Oxygen Species ◽  
Tumor Microenvironment ◽  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Metal Ion ◽  
Reactive Oxygen Species Generation ◽  
Reactive Oxygen ◽  
Oxygen Species

Herein, we design tumor microenvironment specific active nano sono-chemodynamic agent for synergistic photodynamic–chemodynamic cancer therapy.

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