Flexible Gold-Catalyzed Regioselective Oxidative Difunctionalization of Unactivated Alkenes

2011 ◽  
Vol 123 (4) ◽  
pp. 936-940 ◽  
Author(s):  
Teresa de Haro ◽  
Cristina Nevado
Keyword(s):  
Oxidative Difunctionalization

scholarly journals Organo-Redox-Catalysis for the difunctionalization of alkenes and oxidative Ritter reactions by C-H functionalization

2021 ◽  
Author(s):  
Martin Klussmann ◽  
Sensheng Liu
Keyword(s):  
Transition Metals ◽  
Redox Reactions ◽  
Organic Substrates ◽  
Redox Catalysis ◽  
Redox Catalysts ◽  
Oxidative Difunctionalization

Transition metals are the dominant catalysts for redox-reactions between peroxides and organic substrates. Here, we show that triarylamines can act as organic redox-catalysts, enabling oxidative difunctionalization reactions of alkenes and...

Recent Advances in the Intermolecular Oxidative Difunctionalization of Alkenes

2018 ◽  
Vol 19 (2-3) ◽  
pp. 440-451 ◽  
Author(s):  
Jie Lin ◽  
Ren‐Jie Song ◽  
Ming Hu ◽  
Jin‐Heng Li
Keyword(s):  
Recent Advances ◽  
Oxidative Difunctionalization

scholarly journals Synthesis and Biological Evaluation of Furo[3,2-c]pyrazole-5-carbimidates

2019 ◽  
Vol 31 (10) ◽  
pp. 2389-2393
Author(s):  
Sravanthi Siliveri ◽  
Harinadha Babu Vamaraju ◽  
Shivaraj
Keyword(s):  
Antibacterial Activity ◽  
Double Bond ◽  
Spectral Data ◽  
Biological Evaluation ◽  
Significant Protection ◽  
Edema Formation ◽  
Anti Inflammatory ◽  
Alkoxy Groups ◽  
Oxidative Difunctionalization ◽  
Synthesis And Biological Evaluation

In the present work, novel pyrazole fused dihydrofurans synthesized via a chronological addition of N-chloro succinimide and base piperidine to pyrano[3,2-c]pyrazole carbonitrile derivatives in methanol medium. Oxidative difunctionalization was done with the reagent N-chloro succinimide by the addition of both chlorine and alkoxy groups crosswise the chromene double bond. The addition of base results in the construction of dihydrofuran derivatives by ring contraction. The structures of newly synthesized compounds were characterized on the basis of physical and spectral data. Synthesized compounds were evaluated for antibacterial and anti-inflammatory activities. All the compounds exhibited significant antibacterial activity against all the four strains of bacteria and their MICs ranged between 1.56 and 12.55 μg/mL. In anti-inflammatory screening, among all the tested compounds, compounds 7, 8, 9, 11, 12, 13, 14, 16, 17 and 18 exhibited significant protection against the edema formation at a concentration of 100 mg/kg.

Visible-light-promoted oxidative difunctionalization of alkenes with sulfonyl chlorides to access β-keto sulfones under aerobic conditions

2017 ◽  
Vol 58 (37) ◽  
pp. 3667-3671 ◽  
Author(s):  
Teng-fei Niu ◽  
Jing Cheng ◽  
Chang-li Zhuo ◽  
Ding-yun Jiang ◽  
Xing-ge Shu ◽  
...  
Keyword(s):  
Visible Light ◽  
Aerobic Conditions ◽  
Sulfonyl Chlorides ◽  
Oxidative Difunctionalization

Visible-light-induced dual C–C bond formation via selective C(sp3)–H bond cleavage: efficient access to alkylated oxindoles from activated alkenes and simple ethers under metal-free conditions

2017 ◽  
Vol 19 (7) ◽  
pp. 1732-1739 ◽  
Author(s):  
Dong Xia ◽  
Yang Li ◽  
Tao Miao ◽  
Pinhua Li ◽  
Lei Wang
Keyword(s):  
Visible Light ◽  
Bond Cleavage ◽  
Bond Formation ◽  
Metal Free ◽  
Efficient Access ◽  
Oxidative Difunctionalization

A visible-light-induced oxidative difunctionalization of activated alkenes with simple ethersviaselective C(sp3)–H bond cleavage and dual C–C bond formation was developed.

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