Self-Assembled Synthetic Viral Capsids from a 24-mer Viral Peptide Fragment

2010 ◽  
Vol 122 (50) ◽  
pp. 9856-9859 ◽  
Author(s):  
Kazunori Matsuura ◽  
Kenta Watanabe ◽  
Tsubasa Matsuzaki ◽  
Kazuo Sakurai ◽  
Nobuo Kimizuka
2010 ◽  
Vol 49 (50) ◽  
pp. 9662-9665 ◽  
Author(s):  
Kazunori Matsuura ◽  
Kenta Watanabe ◽  
Tsubasa Matsuzaki ◽  
Kazuo Sakurai ◽  
Nobuo Kimizuka

Nanoscale ◽  
2019 ◽  
Vol 11 (21) ◽  
pp. 10160-10166 ◽  
Author(s):  
Idit Kopatz ◽  
Ran Zalk ◽  
Yael Levi-Kalisman ◽  
Efrat Zlotkin-Rivkin ◽  
Gabriel A. Frank ◽  
...  

DNA origami in self-assembled SV40 capsid, a new type of encapsulation substrate for medical applications.


2020 ◽  
Vol 56 (52) ◽  
pp. 7092-7095
Author(s):  
Hiroto Furukawa ◽  
Hiroshi Inaba ◽  
Fumihito Inoue ◽  
Yoshihiro Sasaki ◽  
Kazunari Akiyoshi ◽  
...  

We demonstrated a simple strategy for constructing enveloped artificial viral capsids by self-assembly of anionic artificial viral capsid and lipid bilayer containing cationic lipid.


2017 ◽  
Vol 23 (7-8) ◽  
pp. 636-643 ◽  
Author(s):  
Yoko Nakamura ◽  
Saki Yamada ◽  
Shoko Nishikawa ◽  
Kazunori Matsuura
Keyword(s):  

2013 ◽  
Vol 45 (5) ◽  
pp. 529-534 ◽  
Author(s):  
Kazunori Matsuura ◽  
Kenta Watanabe ◽  
Yoshihiro Matsushita ◽  
Nobuo Kimizuka

2017 ◽  
Vol 15 (23) ◽  
pp. 5070-5077 ◽  
Author(s):  
Seiya Fujita ◽  
Kazunori Matsuura

A β-annulus-coiled-coil-B peptide self-assembled into an artificial viral capsid and then the addition of a complementary coiled-coil-A peptide showed the formation of capsids with coiled-coil spikes on the surface.


2016 ◽  
Vol 14 (33) ◽  
pp. 7869-7874 ◽  
Author(s):  
Kazunori Matsuura ◽  
Tomohiro Nakamura ◽  
Kenta Watanabe ◽  
Takanori Noguchi ◽  
Kosuke Minamihata ◽  
...  

His-tagged proteins were encapsulated into artificial viral capsids self-assembled from Ni-NTA-modified β-annulus peptides.


Nanomaterials ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. 543 ◽  
Author(s):  
Junzheng Wu ◽  
Ying Zhang ◽  
Nenghui Zhang

The condensation of DNA helices has been regularly found in cell nucleus, bacterial nucleoids, and viral capsids, and during its relevant biodetections the attractive interactions between DNA helices could not be neglected. In this letter, we theoretically characterize the elastic properties of double-stranded DNA (dsDNA) self-assembled 2D films and their multiscale correlations with the dynamic detection signals of DNA-microbeams. The comparison of attraction- and repulsion-dominated DNA films shows that the competition between attractive and repulsive micro-interactions endows dsDNA films in multivalent salt solutions with anomalous elastic properties such as tensile surface stresses and negative moduli; the occurrence of the tensile surface stress for the attraction-dominated DNA self-assembled film reveals the possible physical mechanism of the condensation found in organism. Furthermore, dynamic analyses of a hinged–hinged DNA-microbeam reveal non-monotonous frequency shifts due to attraction- or repulsion-dominated dsDNA adsorptions and dynamic instability occurrence during the detections of repulsion-dominated DNA films. This dynamic instability implies the existence of a sensitive interval of material parameters in which DNA adsorptions will induce a drastic natural frequency shift or a jump of vibration mode even with a tiny variation of the detection conditions. These new insights might provide us some potential guidance to achieve an ultra-highly sensitive biodetection method in the future.


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