scholarly journals Benzothiazole and stilbene derivatives as promising positron emission tomography myelin radiotracers for multiple sclerosis

2016 ◽  
Vol 80 (1) ◽  
pp. 166-167 ◽  
Author(s):  
Benedetta Bodini ◽  
Mattia Veronese ◽  
Federico Turkheimer ◽  
Bruno Stankoff
Keyword(s):  
Multiple Sclerosis ◽  
Positron Emission Tomography ◽  
Emission Tomography ◽  
Positron Emission ◽  
Stilbene Derivatives

Imaging central nervous system myelin by positron emission tomography in multiple sclerosis using [methyl-11C]-2-(4′-methylaminophenyl)- 6-hydroxybenzothiazole

2011 ◽  
Vol 69 (4) ◽  
pp. 673-680 ◽  
Author(s):  
Bruno Stankoff ◽  
Leorah Freeman ◽  
Marie-Stéphane Aigrot ◽  
Audrey Chardain ◽  
Frédéric Dollé ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Positron Emission Tomography ◽  
Central Nervous System ◽  
Nervous System ◽  
Emission Tomography ◽  
Positron Emission

scholarly journals Cerebral rituximab uptake in multiple sclerosis: A 89Zr-immunoPET pilot study

2017 ◽  
Vol 24 (4) ◽  
pp. 543-545 ◽  
Author(s):  
Marloes HJ Hagens ◽  
Joep Killestein ◽  
Maqsood M Yaqub ◽  
Guus AMS van Dongen ◽  
Adriaan A Lammertsma ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Positron Emission Tomography ◽  
Central Nervous System ◽  
Monoclonal Antibody ◽  
Emission Tomography ◽  
Positron Emission ◽  
Central Nervous System Penetration ◽  
Relapsing Remitting ◽  
Rapid Effect ◽  
Relapsing Remitting Multiple Sclerosis

Previous studies have demonstrated that the chimeric monoclonal antibody rituximab significantly reduces clinical and radiological disease activity in relapsing-remitting multiple sclerosis as early as 4 weeks after the first administration. The exact mechanisms leading to this rapid effect have not yet been clarified. The aim of this positron emission tomography study was to assess central nervous system penetration as a possible explanation, using zirconium-89-labelled rituximab. No evidence was found for cerebral penetration of [89Zr]rituximab.

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

10.3791/62094 ◽  
2021 ◽  
Author(s):  
Daniele de Paula Faria ◽  
Caroline Cristiano Real ◽  
Larissa Estessi de Souza ◽  
Alexandre Teles Garcez ◽  
Fabio Luis Navarro Marques ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Positron Emission Tomography ◽  
Rat Model ◽  
Positron Emission Tomography Imaging ◽  
Emission Tomography ◽  
Tomography Imaging ◽  
Positron Emission
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