scholarly journals Association between bilateral oophorectomy and cognitive decline in older women from the Baltimore Longitudinal Study of Aging

2021 ◽  
Vol 17 (S6) ◽  
Author(s):  
Rebekah Reuben ◽  
Yang An ◽  
Susan M. Resnick ◽  
Gillian Einstein
Keyword(s):  
Longitudinal Study ◽  
Cognitive Decline ◽  
Older Women ◽  
Bilateral Oophorectomy ◽  
Baltimore Longitudinal Study

scholarly journals Pulse Pressure and Pulse Wave Velocity Are Related to Cognitive Decline in the Baltimore Longitudinal Study of Aging

Hypertension ◽  
2008 ◽  
Vol 51 (1) ◽  
pp. 99-104 ◽  
Author(s):  
Shari R. Waldstein ◽  
S. Carrington Rice ◽  
Julian F. Thayer ◽  
Samer S. Najjar ◽  
Angelo Scuteri ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Pulse Wave Velocity ◽  
Cognitive Decline ◽  
Wave Velocity ◽  
Pulse Pressure ◽  
Pulse Wave ◽  
Baltimore Longitudinal Study

scholarly journals Longitudinal Association Between Perceived Fatigability and Cognitive Function in Older Adults: Results from the Baltimore Longitudinal Study of Aging

2019 ◽  
Vol 75 (9) ◽  
pp. e67-e73
Author(s):  
Elizabeth A Salerno ◽  
Amal A Wanigatunga ◽  
Yang An ◽  
Jacek K Urbanek ◽  
Eleanor M Simonsick ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Executive Functions ◽  
Cognitive Decline ◽  
Perceived Exertion ◽  
Rating Of Perceived Exertion ◽  
Future Research ◽  
Mixed Effect ◽  
Age Related ◽  
Baltimore Longitudinal Study

Abstract Background Cognitive decline is consistently associated with diminished life satisfaction and inability to live independently. Identifying early, novel markers of cognitive decline is imperative for improving clinical detection and promoting long-term quality of life. Fatigability, one’s perceived exertion after a standardized walking task, has been associated with declines in physical function; however, it remains unclear as to whether these effects may also extend to cognitive function. Methods We examined whether perceived fatigability, assessed as the rating of perceived exertion (RPE) after a 5 min slow-paced treadmill walk (0.67 m/s, 0% grade), is longitudinally associated with cognitive performance in the domains of memory, executive functions, language, and attention among 934 cognitively intact individuals aged at least 50 years participating in the Baltimore Longitudinal Study of Aging (BLSA); Mage = 69.6 ± 10.1, 51.9% female participants. Continuous associations between RPE and each domain (individual test and composite scores) were assessed using linear mixed-effect models adjusted for demographics and comorbid conditions. Results In fully adjusted models, higher fatigability at baseline was associated with declines in all cognitive domains over an average 2.2 years of follow-up (p < .04 for all). Longitudinally, increased fatigability over time was associated with worsened executive functions (β= −0.01, p = .002). Conclusions These findings suggest that perceived fatigability after a standardized walking task may aid in identification of individuals at a higher risk of future cognitive decline. Future research should examine underlying biological mechanisms contributing to this relationship as well as whether future interventions may target fatigability in midlife to attenuate age-related cognitive decline.

1344: Metabolic Factors Associated with Benign Prostatic Hyperplasia: The Baltimore Longitudinal Study of Aging

2006 ◽  
Vol 175 (4S) ◽  
pp. 432-433 ◽  
Author(s):  
J. Kellogg Parsons ◽  
H. Ballentine Carter ◽  
Alan W. Partin ◽  
B. Gwen Windham ◽  
E. Jeffrey Metter ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Benign Prostatic Hyperplasia ◽  
Prostatic Hyperplasia ◽  
Metabolic Factors ◽  
Factors Associated ◽  
Baltimore Longitudinal Study

scholarly journals Social isolation, rather than loneliness, is associated with cognitive decline in older adults: the China Health and Retirement Longitudinal Study

2021 ◽  
pp. 1-8
Author(s):  
Bin Yu ◽  
Andrew Steptoe ◽  
Yongjie Chen ◽  
Xiaohua Jia
Keyword(s):  
Older Adults ◽  
Longitudinal Study ◽  
Cognitive Function ◽  
Episodic Memory ◽  
Cognitive Decline ◽  
Social Isolation ◽  
Mental Status ◽  
Chinese Older Adults ◽  
Confounding Variables

Abstract Background Social isolation and loneliness have each been associated with cognitive decline, but most previous research is limited to Western populations. This study examined the relationships of social isolation and loneliness on cognitive function among Chinese older adults. Methods This study used two waves of data (2011 and 2015) from the China Health and Retirement Longitudinal Study and analyses were restricted to those respondents aged 50 and older. Social isolation, loneliness, and cognitive function were measured at baseline. Follow-up measures on cognitive function were obtained for 7761 participants (mean age = 60.97, s.d. = 7.31; male, 50.8%). Lagged dependent variable models adjusted for confounding factors were used to evaluate the association between baseline isolation, loneliness, and cognitive function at follow-up. Results Loneliness was significantly associated with the cognitive decline at follow-up (episodic memory: β = −0.03, p < 0.01; mental status: β = −0.03, p < 0.01) in the partially adjusted models. These associations became insignificant after additional confounding variables (chronic diseases, health behaviors, disabilities, and depressive symptoms) were taken into account (all p > 0.05). By contrast, social isolation was significantly associated with decreases in all cognitive function measures at follow-up (episodic memory: β = −0.05, p < 0.001; mental status: β = −0.03, p < 0.01) even after controlling for loneliness and all confounding variables. Conclusions Social isolation is associated with cognitive decline in Chinese older adults, and the relationships are independent of loneliness. These findings expand our knowledge about the links between social relationships and the cognitive function in non-Western populations.

Verbal fluency in normal aging and cognitive decline: Results of a longitudinal study

2021 ◽  
Vol 68 ◽  
pp. 101195
Author(s):  
Claudia Frankenberg ◽  
Jochen Weiner ◽  
Maren Knebel ◽  
Ayimunishagu Abulimiti ◽  
Pablo Toro ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Decline ◽  
Verbal Fluency ◽  
Normal Aging
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