scholarly journals Association Between Accelerated Multimorbidity and Age-Related Cognitive Decline in Older Baltimore Longitudinal Study of Aging Participants without Dementia

2016 ◽  
Vol 64 (5) ◽  
pp. 965-972 ◽  
Author(s):  
Elisa Fabbri ◽  
Yang An ◽  
Marco Zoli ◽  
Toshiko Tanaka ◽  
Eleanor M. Simonsick ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Decline ◽  
Age Related ◽  
Baltimore Longitudinal Study ◽  
Age Related Cognitive Decline

Visual Search Load Effects on Age-Related Cognitive Decline: Evidence From the Yakumo Longitudinal Study

2017 ◽  
Vol 130 (1) ◽  
pp. 73 ◽  
Author(s):  
Takeshi Hatta ◽  
Kimiko Kato ◽  
Chie Hotta ◽  
Mari Higashikawa ◽  
Akihiko Iwahara ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Visual Search ◽  
Cognitive Decline ◽  
Age Related ◽  
Load Effects ◽  
Age Related Cognitive Decline

scholarly journals Longitudinal Association Between Perceived Fatigability and Cognitive Function in Older Adults: Results from the Baltimore Longitudinal Study of Aging

2019 ◽  
Vol 75 (9) ◽  
pp. e67-e73
Author(s):  
Elizabeth A Salerno ◽  
Amal A Wanigatunga ◽  
Yang An ◽  
Jacek K Urbanek ◽  
Eleanor M Simonsick ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Function ◽  
Executive Functions ◽  
Cognitive Decline ◽  
Perceived Exertion ◽  
Rating Of Perceived Exertion ◽  
Future Research ◽  
Mixed Effect ◽  
Age Related ◽  
Baltimore Longitudinal Study

Abstract Background Cognitive decline is consistently associated with diminished life satisfaction and inability to live independently. Identifying early, novel markers of cognitive decline is imperative for improving clinical detection and promoting long-term quality of life. Fatigability, one’s perceived exertion after a standardized walking task, has been associated with declines in physical function; however, it remains unclear as to whether these effects may also extend to cognitive function. Methods We examined whether perceived fatigability, assessed as the rating of perceived exertion (RPE) after a 5 min slow-paced treadmill walk (0.67 m/s, 0% grade), is longitudinally associated with cognitive performance in the domains of memory, executive functions, language, and attention among 934 cognitively intact individuals aged at least 50 years participating in the Baltimore Longitudinal Study of Aging (BLSA); Mage = 69.6 ± 10.1, 51.9% female participants. Continuous associations between RPE and each domain (individual test and composite scores) were assessed using linear mixed-effect models adjusted for demographics and comorbid conditions. Results In fully adjusted models, higher fatigability at baseline was associated with declines in all cognitive domains over an average 2.2 years of follow-up (p < .04 for all). Longitudinally, increased fatigability over time was associated with worsened executive functions (β= −0.01, p = .002). Conclusions These findings suggest that perceived fatigability after a standardized walking task may aid in identification of individuals at a higher risk of future cognitive decline. Future research should examine underlying biological mechanisms contributing to this relationship as well as whether future interventions may target fatigability in midlife to attenuate age-related cognitive decline.

scholarly journals Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0204833 ◽  
Author(s):  
Asri Maharani ◽  
Piers Dawes ◽  
James Nazroo ◽  
Gindo Tampubolon ◽  
Neil Pendleton ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Decline ◽  
Cataract Surgery ◽  
Age Related ◽  
Age Related Cognitive Decline ◽  
English Longitudinal Study

scholarly journals Correction: Cataract surgery and age-related cognitive decline: A 13-year follow-up of the English Longitudinal Study of Ageing

PLoS ONE ◽  
2018 ◽  
Vol 13 (11) ◽  
pp. e0208045 ◽  
Author(s):  
Asri Maharani ◽  
Piers Dawes ◽  
James Nazroo ◽  
Gindo Tampubolon ◽  
Neil Pendleton ◽  
...  
Keyword(s):  
Longitudinal Study ◽  
Cognitive Decline ◽  
Cataract Surgery ◽  
Age Related ◽  
Age Related Cognitive Decline ◽  
English Longitudinal Study

Dietary intake of unsaturated fatty acids and age-related cognitive decline: A 8.5-year follow-up of the Italian Longitudinal Study on Aging

2006 ◽  
Vol 27 (11) ◽  
pp. 1694-1704 ◽  
Author(s):  
Vincenzo Solfrizzi ◽  
Anna Maria Colacicco ◽  
Alessia D’Introno ◽  
Cristiano Capurso ◽  
Francesco Torres ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Longitudinal Study ◽  
Dietary Intake ◽  
Cognitive Decline ◽  
Unsaturated Fatty Acids ◽  
Age Related ◽  
Age Related Cognitive Decline

Activity Engagement in Cognitive Aging: A Review of the Evidence

2013 ◽  
Vol 23 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Yvonne Rogalski ◽  
Muriel Quintana
Keyword(s):  
Older Adults ◽  
Cognitive Decline ◽  
Cognitive Aging ◽  
Social Activity ◽  
Current Evidence ◽  
Omega 3 ◽  
Neuroprotective Effects ◽  
Activity Engagement ◽  
Age Related ◽  
Age Related Cognitive Decline

The population of older adults is rapidly increasing, as is the number and type of products and interventions proposed to prevent or reduce the risk of age-related cognitive decline. Advocacy and prevention are part of the American Speech-Language-Hearing Association’s (ASHA’s) scope of practice documents, and speech-language pathologists must have basic awareness of the evidence contributing to healthy cognitive aging. In this article, we provide a brief overview outlining the evidence on activity engagement and its effects on cognition in older adults. We explore the current evidence around the activities of eating and drinking with a discussion on the potential benefits of omega-3 fatty acids, polyphenols, alcohol, and coffee. We investigate the evidence on the hypothesized neuroprotective effects of social activity, the evidence on computerized cognitive training, and the emerging behavioral and neuroimaging evidence on physical activity. We conclude that actively aging using a combination of several strategies may be our best line of defense against cognitive decline.

scholarly journals Targeting impaired nutrient sensing with repurposed therapeutics to prevent or treat age-related cognitive decline and dementia: A systematic review

2021 ◽  
Vol 67 ◽  
pp. 101302
Author(s):  
Benjamin Kioussis ◽  
Camilla S.L. Tuttle ◽  
Daniel S. Heard ◽  
Brian K. Kennedy ◽  
Nicola T. Lautenschlager ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Decline ◽  
Nutrient Sensing ◽  
Age Related ◽  
Age Related Cognitive Decline
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