scholarly journals The relationship of a white matter hyperintensities rating scale and cognition among Mexican Americans

2020 ◽  
Vol 16 (S5) ◽  
Author(s):  
Raul Vintimilla ◽  
Kevin King ◽  
Meredith N. Braskie ◽  
Kristine Yaffe ◽  
Arthur W. Toga ◽  
...  
2010 ◽  
Vol 6 (4) ◽  
pp. S296
Author(s):  
Melissa J. Slavin ◽  
Brian Draper ◽  
Wei Wen ◽  
Henry Brodaty ◽  
Nicole A. Kochan ◽  
...  

2013 ◽  
Vol 30 (2) ◽  
pp. 219-229 ◽  
Author(s):  
Steven I. Pfeiffer ◽  
Solange Muglia Wechsler

There is a considerable amount of literature on leadership, particularly as it relates to organizations, government, and the military. However, educators and psychologists know considerably less about early precursors of leadership, how leadership develops in youth, possible gender differences, and the relationship of leadership, intelligence and creativity. A global consensus exists that leaders are needed and that we shouldn't delay the early development of leadership skills. The authors propose a model to enhance creative leadership and introduce a teacher-completed rating scale, the Gifted Rating Scales to help accomplish this. As demonstrated, there are possibilities to detect early creative and intellectual giftedness among children and youngsters in the classrooms and expectations to move from a basic level of competence to reach an elite or expert level in any field, facilitating the emergence of leadership.


2018 ◽  
Vol 132 (23) ◽  
pp. 2509-2518 ◽  
Author(s):  
Gargi Mahapatra ◽  
S. Carrie Smith ◽  
Timothy M. Hughes ◽  
Benjamin Wagner ◽  
Joseph A. Maldjian ◽  
...  

Blood-based bioenergetic profiling has promising applications as a minimally invasive biomarker of systemic bioenergetic capacity. In the present study, we examined peripheral blood mononuclear cell (PBMC) mitochondrial function and brain morphology in a cohort of African Americans with long-standing Type 2 diabetes. Key parameters of PBMC respiration were correlated with white matter, gray matter, and total intracranial volumes. Our analyses indicate that these relationships are primarily driven by the relationship of systemic bioenergetic capacity with total intracranial volume, suggesting that systemic differences in mitochondrial function may play a role in overall brain morphology.


2020 ◽  
Vol 7 (1) ◽  
Author(s):  
Halimatus Saidah

ABSTRAKHubungan tingkat kecemasan emosional ibu Post Partum dengan kejadian Post Partum Blues  sangat penting diketahui karena pada fase ini terjadi perubahan secara fisiologis maupun secara psikologis yang dapat mempengaruhi kelabilan emosional ibu setelah melahirkan. Tujuan dari penelitian ini untuk mengetahui hubungan tingkat kecemasan emosional ibu Post Partum dengan kejadian Post Partum Blues  yang ada dikelurahan sukorame wilayah kerja puskesmas sukorame.Desain yang digunakan pada penelitian ini menggunakan analitik korelasional dengan pendekatan Cross Sectional. Sampel penelitian menggunakan teknik Purposive Sampling, diperoleh jumlah sampel 24 orang responden dengan kriteria responden yaitu ibu Post Partum hari ke 7- minggu ke 2, nifas normal. Pengumpulan data menggunakan lembar ceklist skala Hamilton Anxiety Rating Scale dan kuesioner Edinburgh Post Natal Depression Scale. Analisa data menggunkan uji Sperman Rank.         Tingkat kecemasan emosional ibu post partum sebagian kecil (25,0%) yaitu 6 responden. dan kejadian Post Partum Blues  sebagian besar (62,5%) yaitu 15 responden. Hasil analisa data dengan menggunakan uji Spearmen Rank didapatkan hasil p-value 0,000 taraf signifikan (α = 0,05) dengan demikian ada hubungan antara tingkat kecemasan emosional ibu post partum dengan kejadian Post Partum Blues  di Kelurahan Sukorame wilayah Kerja Puskesmas Sukorame. Dan  nilai koefisien (r) sebesar 0,859 kekuatan korelasi dalam kategori sangat kuat dengan arah positif.Dari hasil penelitian ini dapat disimpulkan adanya hubungan antara tingkat kecemasan emosional ibu post partum dengan kejadian Post Partum Blues  di kelurahan Sukorame wilayah kerja Puskesmas Sukorame. Kata Kunci: Tingkat Kecemasan, Post Partum, dan Kejadian Post Partum Blues  ABSTRACT       The relationship between the level of emotional anxiety of the mother of post partum with Post Partum Blues  occurrence is very important because in this phase there is a change physiologically and psychologically wich can affect the emotional stability of mother after giving birth.       The purpose of this study to determine the relationship of emotional anxiety level of post partum mother with Post Partum Blues  incident that exist in sukorame’s Village its work area of puskesmas Sukorame.       Design used correlational analytics with cross sectional approach. The sample research using purposive sampling technique, obtained the number of samples 24 respondents with the criteria of respondents is post partum mother day 7 to week 2, its good puerperium. Data’s collection using hamilton anxiety rating scale and       Edinburgh Postnatal Depression Scale. Data’s processing is interpreted according to the classification of each measuring instrument.       The result of the research showed that  the relationship of emotional anxiety level of post partum mother with Post Partum Blues  incidence was the amount of the anxiety level 12,5%, 25% heavy anxiety , medium anxiety 16,6% and mild anxiety 20,9% with Post Partum Blues  event. While those without anxiety were 0% for Post Partum Blues  event.        From the result of this study it can be concluded that almost all postpartum mothers with anxiety that there is in the field of Sukorame work area puskesmas Sukorame experience Post Partum Blues . As for recommendation of this research is holding counseling about how to handle Post Partum Blues .Key Word : Anxiety level, Post Partum, Post Partum Blues  Event


Stroke ◽  
2005 ◽  
Vol 36 (10) ◽  
pp. 2126-2131 ◽  
Author(s):  
Christian Bocti ◽  
Richard H. Swartz ◽  
Fu-Qiang Gao ◽  
Demetrios J. Sahlas ◽  
Pearl Behl ◽  
...  

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Daiki Takano ◽  
Takashi Yamazaki ◽  
Tetsuya Maeda ◽  
Yuichi Satoh ◽  
Yasuko Ikeda ◽  
...  

[Introduction] White matter hyperintensities (WMH) are considered manifestation of arteriosclerotic small vessel disease and WMH burden increases risk of ischemic stroke and cognitive decline. There are only a few evidences concerning the relationship between polyunsaturated fatty acids (PUFA) and WMH. The present study was designed to elucidate the association between WMH and PUFA profile including eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (AA) in patients with Alzheimer’s disease (AD). [Methods] The present study was based on 119 patients who were diagnosed as having a probable AD according to the NINCDS-ADRDA criteria. Their mean age was 78.3 years old. All subjects underwent neuropsychological evaluation including mini mental state exam (MMSE) and 1.5-Tesla MRI. Fasting blood samples were also collected for the PUFA measurements. We measured the ratio of serum EPA, DHA and AA concentration to the total PUFA concentration. The WMH were evaluated on T2-weight images and classified into periventricular hyperintensity (PVH) and deep white matter hyperintensity (DWMH). The severity of WMH was graded 5 categories. We investigated the relationship between WMH and PUFA profiles. [Results] The EPA ratio correlated negatively with both PVH (rs=-0.2036, p=0.0264) and DWMH grade (rs=-0.3155, p=0.0005). It remained still significant after adjustment for age, sex, statins use, antithrombotics use, mean blood pressure and presence of hypertension (standardized partial regression coefficient(β)=-0.2516, p=0.0122 for PVH, β=-0.3598, p=0.0001 for DWMH). Neither DHA nor AA ratio correlated with DWMH or PVH grade. The EPA ratio but not DHA or AA ratio correlated positively with total MMSE score (rs=0.2310, p=0.0115). [Conclusions] Our data revealed that the serum EPA was protective against WMH as well as cognitive decline in AD patients. Pathophysiology underlying WMH is complex and the possible mechanisms involved in the pathogenesis of WMH encompass incomplete brain ischemia, increased permeability of blood-brain barrier, and inflammation responses. The relationship between serum EPA and WMH can be partly explained by those anti-ischemic and anti-arteriosclerotic effects of EPA.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Yan Chen ◽  
Renyuan Liu ◽  
Shuwei Qiu ◽  
Yun Xu

Introduction: Cerebral White matter hyperintensities(WMH) are frequent findings on MRI scan. They are well known to correlate with vascular cognitive impairment(VCI). However, controversies still remain about the relationship between WMH locations and cognitive function across studies. Hypothesis: Periventricular WMHs(PWH) rather than deep WMHs(DWH) are associated with cognitive decline in VCI. Methods: Fifty-nine subjects with WMHs on MRI were divided into three groups, normal control(NC), mild cognitive impairment(MCI) and vascular dementia(VaD), according to clinical manifestation and neuropsychological performance. WMH volumes were evaluated by Fazekas rating scale and segmental volumetric. Correlations between cognitive performance and WMH volumes were determined in virtue of Spearman correlation analysis. Receiver operator characteristic (ROC) curves were generated to define the classification cut-off value of WMH volumes for distinguishing VCI versus normal controls. Multiple linear regression analysis was used to predict cognitive performance with WMH volumes and locations after adjusting for sex ,age and education level. Results: Cognitive capacities were gradually declined from NC through MCI to VaD patients while WMH volumes and Fazekas scores altered oppositely. Both PWH and DWH volumes and Fazekas scores were correlated with cognitive performance, and moreover, WMH volumes were correlated with Fazekas scores. ROC analysis showed a cut-off value of PWH rather than DWH to distinguish VCI from NC(AUC=0.745 and 0.635, p =0.001 and 0.076, respectively). Linear regression analysis demonstrated that only PWH volumes were associated with cognitive performance( p < 0.001). Conclusion: Our study demonstrate that PWHs are independent predictors for vascular contribution in white matter lesions and suggest clinicians that PWH should be emphasized on evaluating vascular cognitive impairment related with white matter load.


2018 ◽  
Vol 28 (2) ◽  
pp. 105 ◽  
Author(s):  
Kim Pulvers ◽  
A. Paula Cupertino ◽  
Taneisha S. Scheuermann ◽  
Lisa Sanderson Cox ◽  
Yen-Yi Ho ◽  
...  

<p><strong>Background: </strong>Higher smoking prevalence and quantity (cigarettes per day) has been linked to acculturation in the United States among Latinas, but not Latino men. Our study examines variation between a dif­ferent and increasingly important target behavior, smoking level (nondaily vs daily) and acculturation by sex.</p><p><strong>Methods: </strong>An online English-language sur­vey was administered to 786 Latino smokers during July through August 2012. The Brief Acculturation Rating Scale for Mexican Americans–II (ARSMA-II) and other accul­turation markers were used. Multinomial lo­gistic regression models were implemented to assess the association between smoking levels (nondaily, light daily, and moderate/ heavy daily) with acculturation markers.</p><p><strong>Results: </strong>Greater ARMSA-II scores (rela­tive risk ratio, <em>RRR</em>=.81, 95% CI: .72-.91) and being born inside the United States (<em>RRR</em>=.42, 95% CI: .24-.74) were associated with lower relative risk of nondaily smoking. Greater Latino orientation (<em>RRR</em>=1.29, 95% CI: 1.11-1.48) and preference for Spanish language (<em>RRR</em>=1.06, 95% CI: 1.02-1.10) and media (<em>RRR</em>=1.12, 95% CI: 1.05-1.20) were associated with higher relative risk of nondaily smoking. The relationship between acculturation and smoking level did not differ by sex.</p><p><strong>Conclusion: </strong>This study found that among both male and female, English-speaking Latino smokers, nondaily smoking was associated with lower acculturation, while daily smoking was linked with higher ac­culturation.</p><p><em>Ethn Dis. </em>2018.28(2):105-114; doi:10.18865/ed.28.2.105.</p>


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