scholarly journals Association of brain amyloid accumulation and glucose hypometabolism with memory loss

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Ying Wang ◽  
Qi Huang ◽  
Shuhua Ren ◽  
Lin Huang ◽  
Donglang Jiang ◽  
...  
Keyword(s):  
Memory Loss ◽  
Amyloid Accumulation ◽  
With Memory ◽  
Glucose Hypometabolism

Role of MicroRNA Genes miR-1000 and miR-375 in Forming Olfactory Conditional Memory in Drosophila melanogaster

MicroRNA ◽  
2020 ◽  
Vol 09 ◽  
Author(s):  
Sadniman Rahman ◽  
Chaity Modak ◽  
Mousumi Akter ◽  
Mohammad Shamimul Alam
Keyword(s):  
Learning And Memory ◽  
Short Term Memory ◽  
Memory Loss ◽  
Memory Formation ◽  
Neural Integration ◽  
Significant Difference ◽  
Locomotion Speed ◽  
Microrna Genes ◽  
With Memory

Background: Learning and memory is basic aspects in neurogenetics as most of the neurological disorders start with dementia or memory loss. Several genes associated with memory formation have been discovered. MicroRNA genes miR-1000 and miR-375 were reported to be associated with neural integration and glucose homeostasis in some insects and vertebrates. However, neuronal function of these genes is yet to be established in D. melanogaster. Objective: Possible role of miR-1000 and miR-375 in learning and memory formation in this fly has been explored in the present study. Methods: Both appetitive and aversive olfactory conditional learning were tested in the miR-1000 and miR-375 knockout (KO) strains and compared with wild one. Five days old third instar larvae were trained by allowing them to be associated with an odor with reward (fructose) or punishment (salt). Then, the larvae were tested to calculate their preferences to the odor trained with. Learning index (LI) values and larval locomotion speed were calculated for all strains. Results: No significant difference was observed for larval locomotion speed in mutant strains. Knockout strain of miR-1000 showed significant deficiency in both appetitive and aversive memory formation whereas miR-375 KO strain showed a significantly lower response only in appetitive one. Conclusion: The results of the present study indicate important role played by these two genes in forming short-term memory in D. melanogaster.

Many caregivers of persons with memory loss or Alzheimer's disease are unaware of the abilities of their persons with AD to recall their drugs and medical histories

Dementia ◽  
2018 ◽  
pp. 147130121882096
Author(s):  
Thomas A Ala ◽  
GaToya Simpson ◽  
Marshall T Holland ◽  
Vajeeha Tabassum ◽  
Maithili Deshpande ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Memory Loss ◽  
Medical Histories ◽  
With Memory

scholarly journals Narrating a Valley in Max Frisch’s Der Mensch erscheint im Holozän: Material Agency, Rain, and the Geologic Past

Humanities ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 43
Author(s):  
Kiley M. Kost
Keyword(s):  
Climate Change ◽  
Memory Loss ◽  
Careful Consideration ◽  
Temporal Scale ◽  
Careful Examination ◽  
Embodied Experience ◽  
Material Ecocriticism ◽  
Material Agency ◽  
With Memory

The complex narrative composition of image and text in Max Frisch’s Der Mensch erscheint im Holozän discloses entanglements between humans and nonhuman entities that impact the narrative and that demand careful consideration. The story depicts the aging protagonist’s struggle with memory loss and his careful examination of the valley’s mountain formations in fear of a landslide. In this analysis, I show that both of these threats can be read as entangled with nonhuman agents. By focusing on the material dimension of the text, two central and related shifts occur: the background element of rain becomes foregrounded in the narrative, and the natural formations of the valley that are assumed to be static are revealed to be dynamic. These shifts lead to an interpretation of Frisch’s text focused on the impacts of rain and the temporal scale of the text’s geologic dimension. Approaching the text through the lens of material ecocriticism unveils the multiple agencies at play, decenters the human, and illustrates the embodied experience of climate change.

scholarly journals New Frontiers in Caregiving Research: Biopsychosocial Perspectives and Interventions

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 615-615
Author(s):  
Jyoti Savla ◽  
Karen Roberto ◽  
Mamta Sapra
Keyword(s):  
Family Caregivers ◽  
Memory Loss ◽  
Well Being ◽  
Psychoeducational Intervention ◽  
Loved One ◽  
Daily Diary Study ◽  
Physiological Processes ◽  
And Coping ◽  
With Memory ◽  
Health And Well Being

Abstract Although families embrace the opportunity to care for a loved one, caregiving is stressful and takes a toll on the caregiver’s health and well-being. Earlier studies of stress and coping among family caregivers focused on psychological outcomes and emotional well-being. In the last decade, stress researchers have broadened their focus to include biomarkers and health outcomes. Data from two studies of caregivers of persons with memory loss will be used to discuss two new frontiers of caregiving research. First, a daily-diary study will be used to identify the mechanism by which stress disrupts the physiological processes and proliferates into serious psychopathology and pre-clinical and clinical health conditions. Second, a mindfulness-based psychoeducational intervention study will be utilized to identify malleable factors that can be harnessed to lower stress and improve the well-being of family caregivers. Next steps for caregiving research in the context of demographic and technological trends will be discussed.

scholarly journals Communicating through music: creating accessible songs for Individuals with memory loss

2021 ◽  
Author(s):  
Hallie Anthony
Keyword(s):  
Verbal Memory ◽  
Memory Loss ◽  
Research Process ◽  
Future Research ◽  
Human Communication ◽  
Information Retention ◽  
Scholarly Literature ◽  
Musical Compositions ◽  
Original Musical ◽  
With Memory

This Major Research Paper (MRP) is a research-­creation project that explores the role, impact and influence of music n human communication. More specifically, this MRP investigates the way that music can assist in cognitive comprehension and information retention in individuals with varied forms of memory loss and considers the ways that music can be used to assist in aiding verbal memory and communicating emotion. It also offers insight on methods that could be utilized to further study this area of research. As a research-­creation project, this MRP includes three original musical compositions (Composition A1, Composition B2, and Composition C3) that were developed in response to the scholarly literature on this topic. The three musical compositions that have been produced for this project aim to communicate emotion, create aesthetic satisfaction, and aid in reinforcing the production of memories based on the information presented in the compositions. The composition creation process was informed by information gathered throughout the research process that addresses topics such as: the influence of music on individual listeners, emotion in music, and musical techniques that can be used to successfully communicate ideas. Beyond the scope of this MRP/research-­creation project, these compositions aim to serve as a basis for testing cognitive function in individuals with varied forms of memory loss. Detailed discussion of the design of the musical compositions, including information related to the composition influences, and a breakdown of each composition are included alongside the MRP’s focus on scholarly literature and research. Furthermore, the potential implications of these compositions, including the ways they could assist in future research, is discussed.

scholarly journals Brain amyloid accumulation and glucose hypometabolism in Chinese Alzheimer’s disease population

2020 ◽  
Vol 16 (S4) ◽  
Author(s):  
Shuhua Ren ◽  
Qi Huang ◽  
Donglang Jiang ◽  
Lin Huang ◽  
Ying Wang ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Amyloid Accumulation ◽  
Glucose Hypometabolism

scholarly journals Negotiating the Joint Career: Couples Adapting to Alzheimer's and Aging in Place

2012 ◽  
Vol 2012 ◽  
pp. 1-12 ◽  
Author(s):  
Renée L. Beard ◽  
Sasha Sakhtah ◽  
Vanessa Imse ◽  
James E. Galvin
Keyword(s):  
Population Aging ◽  
Qualitative Interviews ◽  
Aging In Place ◽  
Memory Loss ◽  
Community Services ◽  
Cognitive Status ◽  
Care Practices ◽  
The Impact ◽  
With Memory ◽  
Analyze Data

To understand the impact of memory loss on aging in place, this paper investigated dyads where one spouse had been diagnosed with memory loss. In-depth qualitative interviews were conducted with ten couples (N=20). Grounded theory methods were used to collect, code, and analyze data into themes. Data revealed consensus among and between dyads that it was best to focus on living, rather than what had been or might someday be lost. Nonetheless, differences according to gender and cognitive status (e.g., diagnosed or spouse) were reported. Given population aging, identifying the impact of gender roles and social norms on the potential for aging in place with memory loss is critical. Community services and care practices must be sensitive to the ways that couples prioritized and organized their relationship prior to diagnosis in order to encourage positive patterns of care between couples, foster successful adaptation to changing needs, and support in-home arrangements as long as possible.

INTRADURAL CLIVAL CHORDOMA AND ECCHORDOSIS PHYSALIPHORA

Neurosurgery ◽  
2009 ◽  
Vol 64 (2) ◽  
pp. E387-E388 ◽  
Author(s):  
Riccardo Ciarpaglini ◽  
Ernesto Pasquini ◽  
Diego Mazzatenta ◽  
Andrea Ambrosini-Spaltro ◽  
Vittorio Sciarretta ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Memory Loss ◽  
Histological Findings ◽  
Postoperative Radiation ◽  
Resonance Imaging ◽  
Postoperative Radiation Therapy ◽  
Ecchordosis Physaliphora ◽  
Subtotal Removal ◽  
With Memory

Abstract OBJECTIVE Purely intradural clival chordomas are rare neoplasms, and only a few cases have been reported. The reported cases present features similar to ecchordosis physaliphora, which is a notochordal remnant. We describe these 2 entities and their differential diagnoses, clinical courses, and management. This is the first reported case to be treated using a neuroendoscopic technique. CLINICAL PRESENTATION A 60-year-old man presenting with memory loss underwent magnetic resonance imaging, which revealed an intradural retroclival mass without bone involvement. INTERVENTION The patient underwent an endoscopic transsphenoidal-transclival procedure with subtotal removal of the tumor. Histological findings confirmed the diagnosis of a chordoma. CONCLUSION Even if some parameters exist for a differential diagnosis, ecchordosis physaliphora and intradural chordoma may represent different aspects of the spectrum of the same pathology. Intradural clival chordomas have a better prognosis with respect to classic chordomas. Therefore, in subtotal removal such as that performed in our case, postoperative radiation therapy should be performed only if a regrowth of the remnant is seen during neuroradiological follow-up.

Sign in / Sign up

Export Citation Format

Share Document