Angioedema of the upper aerodigestive tract: risk factors associated with airway intervention and management algorithm

2014 ◽  
Vol 4 (3) ◽  
pp. 239-245 ◽  
Author(s):  
Christopher D. Brook ◽  
Anand K. Devaiah ◽  
Elizabeth M. Davis
2013 ◽  
Vol 149 (2_suppl) ◽  
pp. P46-P46
Author(s):  
Christopher Brook ◽  
Anand K. Devaiah ◽  
Elizabeth Mahoney

Surgery ◽  
2002 ◽  
Vol 131 (1) ◽  
pp. S1-S6 ◽  
Author(s):  
Masaru Morita ◽  
Hiroshi Saeki ◽  
Masaki Mori ◽  
Hiroyuki Kuwano ◽  
Keizo Sugimachi

Epigenetics ◽  
2012 ◽  
Vol 7 (3) ◽  
pp. 270-277 ◽  
Author(s):  
Samson Mani ◽  
Kasia Szymańska ◽  
Cyrille Cuenin ◽  
David Zaridze ◽  
Karen Balassiano ◽  
...  

2002 ◽  
Vol 99 (2) ◽  
pp. 267-272 ◽  
Author(s):  
Christine M. Kasum ◽  
David R. Jacobs ◽  
Kristin Nicodemus ◽  
Aaron R. Folsom

2010 ◽  
Vol 46 (3) ◽  
pp. 588-598 ◽  
Author(s):  
D.I. Conway ◽  
P.A. McKinney ◽  
A.D. McMahon ◽  
W. Ahrens ◽  
N. Schmeisser ◽  
...  

2018 ◽  
Vol 159 (2) ◽  
pp. 320-327 ◽  
Author(s):  
Mitchell L. Worley ◽  
Evan M. Graboyes ◽  
Julie Blair ◽  
Suhael Momin ◽  
Kent E. Armeson ◽  
...  

Objective To describe swallowing outcomes in elderly patients undergoing microvascular reconstruction of the upper aerodigestive tract and identify risk factors for poor postoperative swallowing function. Study Design Case series with chart review. Setting Academic medical center. Subjects and Methods Sixty-six patients aged ≥70 years underwent microvascular reconstruction of the upper aerodigestive tract. The primary outcome measure was the Functional Oral Intake Scale (FOIS); preoperative and postoperative scores were dichotomized to define “good swallowing” and “poor swallowing.” Logistic regression was performed to identify risk factors for poor postoperative swallowing function. Results In total, 91% of reconstructions were performed for oncologic defects. The most common defect site was the oral cavity (67%), and the anterolateral thigh (29%) was the most frequently used donor site. At 3-year follow up, 75% of patients had good swallowing function with 95% of patients who achieved good swallowing function doing so within 6 months of surgery. On multivariable analysis, patients with pT4 tumors (odds ratio [OR], 5.2; 95% confidence interval [CI], 1.0-25.6) and those undergoing at least partial glossectomy (OR, 4.7; 95% CI, 1.1-20.7) were more likely to experience poor swallowing function at 6-month follow-up. Conclusion Approximately half of elderly patients achieve good swallowing function within 6 months following microvascular reconstruction of the upper aerodigestive tract. Elderly patients with pT4 tumors and those requiring glossectomy are at highest risk for poor swallowing outcomes. These data can be used to inform preoperative patient counseling and design interventions aimed at improving swallowing function in those at high risk for poor outcomes.


PEDIATRICS ◽  
1994 ◽  
Vol 94 (1) ◽  
pp. 113-114
Author(s):  
Roger W. Byard

Sudden collapse due to acute upper aerodigestive tract obstruction in infants and young children is most often caused by ingested food or toy parts.1,2 Although attention has been previously drawn to the different pattern of food asphyxiation in children compared with adults,2 the following two cases taken from the autopsy files of the Adelaide Children's Hospital over a 20-year period demonstrate particular risk factors associated with young children eating in daycare centers. CASE REPORTS Case 1 A 19-month-old healthy boy was eating a sausage happily in a daycare center when last observed by a caretaker who was then absent for several minutes.


2017 ◽  
Vol 35 (15_suppl) ◽  
pp. 1542-1542
Author(s):  
Kenro Hirata ◽  
Akira Yokoyama ◽  
Rieko Nakamura ◽  
Tai Omori ◽  
Hirofumi Kawakubo ◽  
...  

1542 Background: Squamous cell dysplasia and carcinoma in the upper aerodigestive tract (UAT) was frequently accompanied by melanosis in the UAT. Soft palatal melanosis can be detected by visual inspection during routine physical examination or even personally in a mirror. Methods: We reviewed digitalized records of high-quality endoscopic images of the soft palate of 1786 Japanese alcoholic men who underwent endoscopic screening combined with esophageal iodine staining and evaluated to what extent the presence of soft palatal melanosis combined with other risk factors can predict the risk of UAT neoplasia. Results: Soft palatal melanosis was observed in 381 (21·3%) of the subjects (mild, 15·0%; distinct, 6·3%). An older age, an inactive heterozygous aldehyde dehydrogenase-2 genotype, smoking, and a high mean corpuscular volume (MCV) were positively associated with the presence of soft palatal melanosis. The age-adjusted odds ratio (OR [95% CI]) for neoplasia in the UAT was 1·92 [1·40–2·64] in the group with melanosis and 2·51 (1·55–4·06) in the group with distinct melanosis, compared with the melanosis-free group. A multiple logistic analysis including the alcohol and aldehyde dehydrogenases genotypes and non-genetic risk factors showed that the presence of soft palatal melanosis was independently associated with a high risk of neoplasia in the UAT. We calculated the individual number of risk factors out of four easily identifiable and significant factors: age ≥55 years, current/former alcohol flushing, MCV ≥106 fl, and distinct soft palatal melanosis. Compared with the risk-factor-free condition, the OR (95% CI) values of UAT neoplasia for one, two, three and four risk factors were 1·49 (0·97–2·30), 3·14 (2·02–4·88), 4·80 (2·71–8·51) and 7·80 (2·17–28·1), respectively. Conclusions: Soft palatal melanosis combined with other simple risk assessments provides a simple new strategy for identifying heavy drinkers with a high risk for UAT neoplasia.


Sign in / Sign up

Export Citation Format

Share Document