Weak Bases‐Mediated Modified Favorskii Reaction‐Type Direct Alkynylation/( E )‐Alkenylation: A Unified Rapid Access to α,β‐Unsaturated Ketones and Propargyl Alcohols

2019 ◽  
Vol 8 (12) ◽  
pp. 2257-2268 ◽  
Author(s):  
Mohit K. Tiwari ◽  
Lalit Yadav ◽  
Bharti Rajesh Kumar Shyamlal ◽  
Sandeep Chaudhary
Keyword(s):  
Reaction Type ◽  
Unsaturated Ketones ◽  
Rapid Access ◽  
Weak Bases ◽  
Favorskii Reaction ◽  
Propargyl Alcohols

Visible-light-induced remote C(sp3)-H sulfonylvinylation: assembly of cyanoalkylated vinyl sulfones

2021 ◽  
Author(s):  
Ping Bao ◽  
Feiyan Yu ◽  
Fu-Sheng He ◽  
Zhimei Tang ◽  
Wei-Ping Deng ◽  
...  
Keyword(s):  
Visible Light ◽  
Rapid Access ◽  
Three Component Reaction ◽  
Propargyl Alcohols

A photoinduced sulfonylvinylation of unactivated C(sp3)-H bond through a three-component reaction of propargyl alcohols, potassium metabisulfite and cycloketone oxime esters is developed. This approach enables rapid access to cyanoalkylated vinyl...

Rhodium-Catalyzed Regioselective Double Annulation of Enaminones with Propargyl Alcohols: Rapid Access to Arylnapthalene Lignan Derivatives

2021 ◽  
Author(s):  
Attunuri Nagireddy ◽  
Dattatri ◽  
Ramesh Kotipalli ◽  
Jagadeesh Babu Nanubolu ◽  
Maddi Sridhar Reddy
Keyword(s):  
Rapid Access ◽  
Propargyl Alcohols

ChemInform Abstract: Carbon Dioxide Mediated Catalytic Rearrangement of Propargyl Alcohols into α,β-Unsaturated Ketones.

ChemInform ◽  
2008 ◽  
Vol 39 (9) ◽  
Author(s):  
Yudai Sugawara ◽  
Wataru Yamada ◽  
Shunsuke Yoshida ◽  
Taketo Ikeno ◽  
Tohru Yamada
Keyword(s):  
Carbon Dioxide ◽  
Unsaturated Ketones ◽  
Propargyl Alcohols

An iodine-promoted Meyer–Schuster rearrangement for the synthesis of α-iodo unsaturated ketones

2015 ◽  
Vol 2 (5) ◽  
pp. 506-509 ◽  
Author(s):  
Hai-Tao Zhu ◽  
Ming-Jin Fan ◽  
De-Suo Yang ◽  
Xiao-Ling Wang ◽  
Sen Ke ◽  
...  
Keyword(s):  
Unsaturated Ketones ◽  
Propargyl Alcohols

A facile and efficient iodine-promoted Meyer–Schuster rearrangement of propargyl alcohols for the synthesis of α-iodo-α,β-unsaturated ketones is presented.

Carbon Dioxide-Mediated Catalytic Rearrangement of Propargyl Alcohols into α,β-Unsaturated Ketones

2007 ◽  
Vol 129 (43) ◽  
pp. 12902-12903 ◽  
Author(s):  
Yudai Sugawara ◽  
Wataru Yamada ◽  
Shunsuke Yoshida ◽  
Taketo Ikeno ◽  
Tohru Yamada
Keyword(s):  
Carbon Dioxide ◽  
Unsaturated Ketones ◽  
Propargyl Alcohols

Improved synthesis of tertiary propargyl alcohols by the Favorskii reaction of alkyl aryl (hetaryl) ketones with acetylene

2013 ◽  
Vol 49 (1) ◽  
pp. 8-11 ◽  
Author(s):  
E. Yu. Shmidt ◽  
I. A. Bidusenko ◽  
N. I. Protsuk ◽  
A. I. Mikhaleva ◽  
B. A. Trofimov
Keyword(s):  
Alkyl Aryl ◽  
Favorskii Reaction ◽  
Propargyl Alcohols

ChemInform Abstract: Improved Synthesis of Tertiary Propargyl Alcohols by the Favorskii Reaction of Alkyl Aryl (Hetaryl) Ketones with Acetylene.

ChemInform ◽  
2013 ◽  
Vol 44 (25) ◽  
pp. no-no
Author(s):  
E. Yu. Shmidt ◽  
I. A. Bidusenko ◽  
N. I. Protsuk ◽  
A. I. Mikhaleva ◽  
B. A. Trofimov
Keyword(s):  
Alkyl Aryl ◽  
Favorskii Reaction ◽  
Propargyl Alcohols

Modern Annulation Strategies for the Synthesis of Cyclo[b]fused Indoles

Synlett ◽  
2018 ◽  
Vol 30 (03) ◽  
pp. 245-251 ◽  
Author(s):  
Edgar Haak
Keyword(s):  
Broad Spectrum ◽  
Biological Activities ◽  
Molecular Structures ◽  
Selective Synthesis ◽  
Indole Derivatives ◽  
Rapid Access ◽  
Propargyl Alcohols

2,3-Annulated indoles exhibit a broad spectrum of biological activities. Various annulation strategies are applied to generate these scaffolds from prefunctionalized aniline or indole derivatives. Only a few methodologies allow the direct annulation of indole itself, often associated with regioselectivity issues or restrictions on available substitution patterns. More recently, ruthenium-catalyzed cascade transformations of readily available propargyl alcohols have been applied to the selective synthesis of various cyclo[b]fused indoles directly from indole. These efficient processes provide rapid access to intricate molecular structures from simple starting materials and facilitate the preparation of drug-like molecules.

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