Association between the DRD2 A1 allele and opium addiction in the Iranian population

2005 ◽  
Vol 134B (1) ◽  
pp. 39-41 ◽  
Author(s):  
Maria Shahmoradgoli Najafabadi ◽  
Mina Ohadi ◽  
Mohammad Taghi Joghataie ◽  
Faraz Valaie ◽  
Yasser Riazalhosseini ◽  
...  
Keyword(s):  
Iranian Population ◽  
Opium Addiction

Barriers to antiretroviral therapy adherence among prisoners in one prison in Iran

2019 ◽  
Vol 19 ◽  
Author(s):  
Behnam Farhoudi ◽  
Seyed Ahmad Seyedalinaghi ◽  
Masoud Jafarinasab ◽  
Seyed Mohammad Ghavam ◽  
Omid Dadras ◽  
...  
Keyword(s):  
Antiretroviral Therapy ◽  
Patient Adherence ◽  
Social Stigma ◽  
Group Discussion ◽  
Life Quality ◽  
Hiv Treatment ◽  
People Living With Hiv ◽  
Dramatic Improvement ◽  
Art Adherence ◽  
Opium Addiction

Background: Antiretroviral medications have improved the survival and life quality of people living with HIV and turned HIV into a chronic controllable disease. However, the success of HIV treatment depends on many factors; the patient adherence is one the most important indicators which. In this study, we explored the potential barriers to an effective adherence antiretroviral therapy (ART) among the HIV-positive prisoners of Ghezelhesar prison, Iran. Methods: To explore and identify the barriers toward ART adherence, a focus group discussion was held with six prisoners eligible for ART but rejected to be treated or did not retain on ART. The prisoners were recruited through purposive sampling method. All the words, behaviors and even body languages were precisely recorded and analyzed to reach the final results. Results: The most reported obstacles toward ART adherence were the lack of trust in effectiveness of medications and drug complications. Other reasons were inadequate nutrition, lack of amenities, social stigma, lack of economic and psychological support, misbehavior of prison staff and inadequate methadone prescription for those with opium addiction. Conclusion: Due to the results and the fact that adequate Methadone prescription for opium addiction, improving life quality and receiving emotional and medical support from staff could improve adherence to HIV medication in prisoners, comprehensive education of prisoners about their health condition along with staff education may improve the life condition of HIV infected prisoners and may cause dramatic improvement in ART adherence and prisoners health.

Prognostic factors of lupus nephritis in an Iranian population

2017 ◽  
Vol 2 (1) ◽  
pp. 17-22
Author(s):  
Hossein Soleymani Salehabadi ◽  
Hamidreza Bashiri ◽  
Nader Nouri Majelan ◽  
Ali Dehghan ◽  
Mohammadbagher Owlia
Keyword(s):  
Prognostic Factors ◽  
Lupus Nephritis ◽  
Iranian Population

scholarly journals The Prevalence and Patterns of Palmaris Longus Muscle Absence in an Iranian Population

2019 ◽  
Vol 9 (4) ◽  
pp. 279-282
Author(s):  
Mehdi Forouzesh ◽  
Abdolrazagh Barzegar ◽  
Fardin Fallah
Keyword(s):  
Gender Difference ◽  
Clinical Importance ◽  
Tendon Graft ◽  
Iranian Population ◽  
Geographical Variability ◽  
Palmaris Longus ◽  
Longus Muscle ◽  
Palmaris Longus Muscle ◽  
And Gender ◽  
Gender Specific

Palmaris Longus (PL) is a muscle of the forearm, i.e., not functionally necessary and does not exist in all people. It is a choice for tendon graft and investigating its prevalence is of clinical importance. During April-October 2009, 102 cadavers (78 males, 24 females) were bilaterally necropsied for PL exploration in Zanjan City, Iran. PL Absence (PLA) was observed in 37 (36.3%) cases (28 males, 9 females). PLA prevalence was similar in men (36%) and women (37.5%). Of PLA cases, 19 (51%) were unilateral (14 males, 5 females), and 18 (49%) were bilateral (14 males, 4 females). In conclusion, PLA prevalence of 36.3% in our population was similar to other studies conducted in Iran. We found no gender difference in PLA prevalence and its patterns. Due to geographical variability in PLA rate, future regional and national studies with more magnificent sample sizes are recommended to determine the prevalence and gender-specific patterns of PLA.

scholarly journals In silico prediction of HBD gene variants in the Iranian population

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Keivan Moradi ◽  
Aboozar Mohammadi ◽  
Mohsen Kazeminia
Keyword(s):  
Persian Gulf ◽  
Globin Gene ◽  
Iranian Population ◽  
Gene Variants ◽  
In Silico Prediction ◽  
Screening Programs ◽  
Prediction Tools ◽  
Clinical Laboratories ◽  
The Persian Gulf ◽  
Thalassemia Screening

Abstract Background The quantification of hemoglobin A2 (Hb A2; α2δ2) is used as a valuable test to differentiate α- and ß-thal carriers in clinical laboratories. Therefore, the HBD (δ-globin) gene variants could result in reduced levels of Hb A2 and have implications for thalassemia screening programs. The aim of the present study was to predict the consequences of HBD gene variants identified in the Iranome project. Results The highest number of variants was in the Persian Gulf Islanders. The variants of p.Gln132Glu (HBD: c.394C>G), p.Gly17Arg (HBD: c.49G>C), p.Thr5Ile (HBD: c.14C>T), and p.Ala28Ser (HBD: c.82G>T) presented damage results in three or more prediction tools. In addition, it seems that the p.Gly30= (HBD: c.90C>T) decreases the use of authentic splice and, instead, creates a new donor splice site (DSS) or leads to the use of a cryptic DSS. Conclusions Most of these variants have been associated with a decrease in Hb A2 levels. Due to the high mutational diversity in the HBB gene in the Iranian population and the use of Hb A2 quantification to differentiate α- and ß-thal carriers among Iranian clinical laboratories, some attention should be taken to a possible co-inheritance of HBD gene variants to avoid the misdiagnosis of ß-thal carriers.

rs12977 of RAC1 is associated with the progress of gastric cancer in Iranian population

Gene Reports ◽  
2021 ◽  
pp. 101069
Author(s):  
Aliasghar Fallahiyan Javani ◽  
Mohammad Fazilati ◽  
Mansoureh Azadeh ◽  
Kamran Ghaedi
Keyword(s):  
Gastric Cancer ◽  
Iranian Population

Assessment of association between HLA alleles and acquired aplastic anemia in Iranian population

2021 ◽  
Vol 18 ◽  
pp. 100075
Author(s):  
Mohammad Taheri ◽  
Mohammad Taghi Akbari ◽  
Mohammadreza Ostadali ◽  
Amir Ali Hamidieh ◽  
Hamid Fallah ◽  
...  
Keyword(s):  
Aplastic Anemia ◽  
Iranian Population ◽  
Hla Alleles

Investigating the association between rs6983267 polymorphism and susceptibility to gastrointestinal cancers in Iranian population

2021 ◽  
Vol 48 (3) ◽  
pp. 2273-2284
Author(s):  
Farzaneh Karimi ◽  
Seyedeh Mina Amiri-Moghaddam ◽  
Zakieh Bagheri ◽  
Ahmad Reza Bahrami ◽  
Ladan Goshayeshi ◽  
...  
Keyword(s):  
Iranian Population ◽  
Gastrointestinal Cancers

scholarly journals Author Correction: Clinical and genetic spectrum of glycogen storage disease in Iranian population using targeted gene sequencing

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zahra Beyzaei ◽  
Fatih Ezgu ◽  
Bita Geramizadeh ◽  
Mohammad Hadi Imanieh ◽  
Mahmood Haghighat ◽  
...  
Keyword(s):  
Glycogen Storage Disease ◽  
Storage Disease ◽  
Gene Sequencing ◽  
Glycogen Storage ◽  
Iranian Population ◽  
Targeted Gene Sequencing
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