scholarly journals Severe visual loss caused by inhalational methanol poisoning in fireworks production: A report on 3 cases

2021 ◽  
Author(s):  
Lei Luo ◽  
XueQin Zhu ◽  
JiMeng Li ◽  
Feng Yang ◽  
YanYan Xiong ◽  
...  
Keyword(s):  
Visual Loss ◽  
Methanol Poisoning ◽  
Severe Visual Loss

scholarly journals Severe Visual Loss Caused by Inhalational Methanol Poisoning in Fireworks Production: A Report on 3 Cases

2021 ◽  
Author(s):  
Lei Luo ◽  
Xueqin Zhu ◽  
Jimeng Li ◽  
Feng Yang ◽  
YanYan Xiong ◽  
...  
Keyword(s):  
Metabolic Acidosis ◽  
Visual Loss ◽  
Manufacturing Industry ◽  
Occupational Injury ◽  
Inhalation Exposure ◽  
High Concentration ◽  
Methanol Poisoning ◽  
Severe Visual Loss ◽  
Methanol Exposure ◽  
Relationship Of

Abstract BACKGROUND Explosion injury is a common occupational injury with fireworks production. There are few reports about the relationship of severe visual loss and acute methanol poisoning in fireworks laborers. CASE SUMMARY Here we report 3 patients of visual loss caused by inhalation exposure to high concentration of methanol, who were engaged in the granulation process of fireworks manufacturing industry. They presented with severe metabolic acidosis and visual impairments, accompanied with headache, chest tightness, shortness of breath, dizziness and vomiting. One patient developed bilateral blindness and two patients improved after timely hemodialysis treatment.CONCLUSION This case report emphasizes the risk of methanol poisoning in the fireworks industry or other factories using commercial alcohol. Early hemodialysis intervention and metabolic acidosis correction are crucial for rescuing visual impairment caused by methanol exposure. The awareness and supervision of commercial alcohol are indispensable for similar industrial manufactures.

Leber's Hereditary Optic Neuropathy as a Cause of Severe Visual Loss in Childhood

PEDIATRICS ◽  
1993 ◽  
Vol 91 (5) ◽  
pp. 988-989
Author(s):  
C. M. MOORMAN ◽  
J. S. ELSTON ◽  
P. MATTHEWS
Keyword(s):  
Optic Neuropathy ◽  
Visual Loss ◽  
Age Of Onset ◽  
Transmitted Disease ◽  
Point Mutations ◽  
Leber’S Hereditary Optic Neuropathy ◽  
Leber's Hereditary Optic Neuropathy ◽  
Severe Visual Loss ◽  
Sporadic Cases ◽  
Hereditary Optic Neuropathy

Leber's hereditary optic neuropathy (LHON) is a rare, maternally transmitted disease that most commonly causes acute or subacute visual loss in young men, typically between the ages of 17 and 24 years (although perhaps 14% of affected individuals are women), which may be associated with systemic disorders, eg, cardiac dysrhythmias and neurologic problems.1 Onset is usually asymmetric, but intervals between involvement of the two eyes are usually less than a few months. A definitive diagnosis rested on a family history, age of onset, and the characteristic circumpapillary microangiopathy of the optic disc in the acute phase. However, recent demonstration of point mutations of mitochondrial DNA in affected individuals means that confirmation of the diagnosis can now be obtained in atypical or sporadic cases.2

scholarly journals MOG Antibody Positive Optic Perineuritis: an Observational Study in Han Chinese

2021 ◽  
Author(s):  
CHAO MENG ◽  
Jia-wei Wang ◽  
Lei Liu ◽  
Wen-jing Wei ◽  
Jian-hua Tao ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Visual Loss ◽  
Clinical Symptoms ◽  
Optic Chiasm ◽  
Han Chinese ◽  
Younger Patients ◽  
Brainstem Lesions ◽  
Severe Visual Loss ◽  
Mri Changes ◽  
Magnet Resonance

Abstract ObjectiveTo shed light on the clinical characteristics, magnet resonance imaging(MRI) changes, and prognosis of myelin oligodendrocyte glycoprotein antibody (MOG-IgG) positive OPN in Han Chinese.MethodsWe observed 39 MOG-IgG positive patients in our ward from January 1, 2017 , to December 31, 2019. Twenty patients met OPN inclusion criteria included contrast enhancement surrounding the optic nerve, and at least one of the following clinical symptoms: 1) reduction of visual acuity, 2) impairment of visual field, and 3) eye pain. Single course group(n=11) and recurrence group(n=9) were used for comparison. Outcome variables included Wingerchuk visual acuity classification.Results Of the 20 patients with MOG-IgG positive OPN, 12(60%) were women. Ten cases (50%) presented with bilateral and 17 eyes (56.67%) with severe visual loss (SVL,≤ 0.1). Twenty-one(70.00%) eyes showed edema of optic disc. Twenty-five eyes (83.3%) had longitudinally extensive perineural enhancement. At follow-up, 4 (13%) eyes still had SVL, while 26 (87%) eyes had no SVL, and of the 19 ON patients, 3 (9%) eyes still had SVL. Seven patients (35.00%) experienced at least a relapse(median interval 13.5 months ), and of the 19 ON cases, 4 (21%) patients experienced relapse. The relapse occurred more often in younger patients than the older (mean year: 38.00 vs. 45.54 years; P = 0.025). There were no optic chiasm and brainstem lesions.ConclusionsMOG-IgG positive OPN in Han Chinese often causes severe bilateral visual loss and longitudinally extensive perineural lesion. Younger patients are more likely to relapse. Optic chiasm and brainstem lesions were relatively rare.

Bilateral severe visual loss in brucellosis

2004 ◽  
Vol 12 (3) ◽  
pp. 233-236 ◽  
Author(s):  
Murat Tunç ◽  
Hakan Durukan
Keyword(s):  
Visual Loss ◽  
Severe Visual Loss

Unexplained drowsiness and progressive visual loss: Methanol poisoning diagnosed at autopsy

2003 ◽  
Vol 15 (1) ◽  
pp. 97-99 ◽  
Author(s):  
Laurence Weinberg ◽  
Jonathan Stewart ◽  
Jonathan Paul Wyatt ◽  
Joseph Mathew
Keyword(s):  
Visual Loss ◽  
Methanol Poisoning
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