scholarly journals Use of nitrous oxide causing severe visual loss 37 days after retinal surgery

2004 ◽  
Vol 93 (3) ◽  
pp. 464-466 ◽  
Author(s):  
E.J.K. Lee
Keyword(s):  
Nitrous Oxide ◽  
Visual Loss ◽  
Retinal Surgery ◽  
Severe Visual Loss

Leber's Hereditary Optic Neuropathy as a Cause of Severe Visual Loss in Childhood

PEDIATRICS ◽  
1993 ◽  
Vol 91 (5) ◽  
pp. 988-989
Author(s):  
C. M. MOORMAN ◽  
J. S. ELSTON ◽  
P. MATTHEWS
Keyword(s):  
Optic Neuropathy ◽  
Visual Loss ◽  
Age Of Onset ◽  
Transmitted Disease ◽  
Point Mutations ◽  
Leber’S Hereditary Optic Neuropathy ◽  
Leber's Hereditary Optic Neuropathy ◽  
Severe Visual Loss ◽  
Sporadic Cases ◽  
Hereditary Optic Neuropathy

Leber's hereditary optic neuropathy (LHON) is a rare, maternally transmitted disease that most commonly causes acute or subacute visual loss in young men, typically between the ages of 17 and 24 years (although perhaps 14% of affected individuals are women), which may be associated with systemic disorders, eg, cardiac dysrhythmias and neurologic problems.1 Onset is usually asymmetric, but intervals between involvement of the two eyes are usually less than a few months. A definitive diagnosis rested on a family history, age of onset, and the characteristic circumpapillary microangiopathy of the optic disc in the acute phase. However, recent demonstration of point mutations of mitochondrial DNA in affected individuals means that confirmation of the diagnosis can now be obtained in atypical or sporadic cases.2

scholarly journals MOG Antibody Positive Optic Perineuritis: an Observational Study in Han Chinese

2021 ◽  
Author(s):  
CHAO MENG ◽  
Jia-wei Wang ◽  
Lei Liu ◽  
Wen-jing Wei ◽  
Jian-hua Tao ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Visual Loss ◽  
Clinical Symptoms ◽  
Optic Chiasm ◽  
Han Chinese ◽  
Younger Patients ◽  
Brainstem Lesions ◽  
Severe Visual Loss ◽  
Mri Changes ◽  
Magnet Resonance

Abstract ObjectiveTo shed light on the clinical characteristics, magnet resonance imaging(MRI) changes, and prognosis of myelin oligodendrocyte glycoprotein antibody (MOG-IgG) positive OPN in Han Chinese.MethodsWe observed 39 MOG-IgG positive patients in our ward from January 1, 2017 , to December 31, 2019. Twenty patients met OPN inclusion criteria included contrast enhancement surrounding the optic nerve, and at least one of the following clinical symptoms: 1) reduction of visual acuity, 2) impairment of visual field, and 3) eye pain. Single course group(n=11) and recurrence group(n=9) were used for comparison. Outcome variables included Wingerchuk visual acuity classification.Results Of the 20 patients with MOG-IgG positive OPN, 12(60%) were women. Ten cases (50%) presented with bilateral and 17 eyes (56.67%) with severe visual loss (SVL,≤ 0.1). Twenty-one(70.00%) eyes showed edema of optic disc. Twenty-five eyes (83.3%) had longitudinally extensive perineural enhancement. At follow-up, 4 (13%) eyes still had SVL, while 26 (87%) eyes had no SVL, and of the 19 ON patients, 3 (9%) eyes still had SVL. Seven patients (35.00%) experienced at least a relapse(median interval 13.5 months ), and of the 19 ON cases, 4 (21%) patients experienced relapse. The relapse occurred more often in younger patients than the older (mean year: 38.00 vs. 45.54 years; P = 0.025). There were no optic chiasm and brainstem lesions.ConclusionsMOG-IgG positive OPN in Han Chinese often causes severe bilateral visual loss and longitudinally extensive perineural lesion. Younger patients are more likely to relapse. Optic chiasm and brainstem lesions were relatively rare.

Bilateral severe visual loss in brucellosis

2004 ◽  
Vol 12 (3) ◽  
pp. 233-236 ◽  
Author(s):  
Murat Tunç ◽  
Hakan Durukan
Keyword(s):  
Visual Loss ◽  
Severe Visual Loss

Progressive Severe Visual Loss after Long-Term Withdrawal from Thioridazine Treatment

2006 ◽  
Vol 16 (4) ◽  
pp. 651-653 ◽  
Author(s):  
I.A. Chaudhry ◽  
F.A. Shamsi ◽  
M. L. Weitzman
Keyword(s):  
Visual Loss ◽  
Severe Visual Loss

Acute severe visual loss and a brainstem mass

The Lancet ◽  
2012 ◽  
Vol 380 (9855) ◽  
pp. 1790
Author(s):  
Annal D Meleth ◽  
Usha Pinninti ◽  
Robert E Coffee ◽  
Petros E Carvounis
Keyword(s):  
Visual Loss ◽  
Severe Visual Loss
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