The relative ribonucleic acid content of lens and retina during lens induction in the chick

1956 ◽  
Vol 99 (1) ◽  
pp. 131-155 ◽  
Author(s):  
Morris S. McKeehan
1976 ◽  
Vol 27 (5) ◽  
pp. 669 ◽  
Author(s):  
DA Little ◽  
LJ Lambourne

The concentrations of nucleic acids, deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), in ovine uterine tissue were studied to determine whether the ratio RNA/DNA might be used in the bioassay of oestrogenic activity. As the uterus decreased in size with time after ovariectomy, the concentration of DNA increased markedly, but the total content of DNA in the uterus remained constant (mean value 342 ? 8 (SE) mg). The RNA concentration of the tissue decreased during involution, with the result that a highly significant reduction of 33% in the RNA/DNA ratio occurred within 2 weeks of ovariectomy. The ratio decreased further with time. Other ewes were treated for 3 days with diethylstilboestrol dipropionate (10 µg/day), commencing 2 weeks after ovariectomy; the stage of the oestrous cycle at which the ovaries were removed had no effect on the response to the oestrogen. Changes in the nucleic acid concentrations in the uteri of these ewes, and the results obtained during involution, indicate that the RNA/DNA ratio of uterine tissue in ovariectomized ewes has potential as a basis for the bioassay of materials of low oestrogenic potency.


1955 ◽  
Vol 53 (2-3-4) ◽  
pp. 499-501
Author(s):  
Helion Povoa Jr.

RNA was determined in red blood cells of man and other mammals. Our report is based on 41 determinations. Red blood cells of rat showed the highest values in comparison with the blood cells of guinea pig, rabbit, horse and sheep which showed the lowest values, and man with intermediate ones. The method used was a combination of Schimidt and Thanhauser and Schneider extractions with the final reactions of pentose with the orcinol reagent colorimetrically measured.


Nature ◽  
1955 ◽  
Vol 176 (4476) ◽  
pp. 310-310 ◽  
Author(s):  
H. E. WADE
Keyword(s):  

1956 ◽  
Vol 13 (2) ◽  
pp. 141-149 ◽  
Author(s):  
F. DOLJANSKI ◽  
Z. ESHKOL ◽  
D. GIVOL ◽  
E. KAUFMANN ◽  
E. MARGOLIASH

SUMMARY Following the observation that large daily doses of thiourea induced numerous mitoses in the liver of rats [Rachmilewitz, Rosin & Doljanski, 1950], the concomitant chemical changes in the liver and urine of thiourea-treated rats were investigated. It was found that: (1) The mitogenetic reaction, which occurred on the 3rd day of treatment with the drug, was preceded by (a) a decrease in liver catalase activity to 30–50% of the normal within 12 hr; (b) an increase in total liver weight and concentration of liver ribonucleic acid within 2 days. The enlarged liver was normal with respect to protein, lipid, water and deoxyribonucleic acid content. (2) The concentration of liver glycogen decreased markedly on the 1st day of thiourea treatment but returned to normal by the 2nd or 3rd day. (3) During the period of treatment with thiourea there was an increase in the urinary excretion of uric acid, allantoin, and phosphate, as well as glucosuria and polyuria. There was no change in the excretion of urea and total sulphate. (4) All these changes, both in the liver and the urine, were fully reversible on withdrawing the drug.


1997 ◽  
Vol 56 (5) ◽  
pp. 1323-1329 ◽  
Author(s):  
Sylvie Bilodeau-Goeseels ◽  
Gilbert A. Schultz

1967 ◽  
Vol 6 (1) ◽  
pp. 70-72 ◽  
Author(s):  
Giovanni Maraini ◽  
Mario Santori ◽  
Francesco Carta

1969 ◽  
Vol 13 (3) ◽  
pp. 251-265 ◽  
Author(s):  
David M. Hunt ◽  
Barrie Burnet

A method is described for quantifying the phenotypic expression of eyeless using gauged estimates of the mean and standard deviation of the distribution of facet numbers.Gene-environment interactions of four eyeless alleles ey, ey2ey4 and eyK are compared in different genetic backgrounds and on a standardized Pacific background. The original strains differ in mean phenotypic value and in direction of response to variations in the ribonucleic acid content of the larval culture medium, whereas the four Pacific strains are more concordant. Consequently these differences are in part attributable to modifier genes present in the different genetic backgrounds of the original strains. Modifier genes also influence the periods in development at which eyeless is sensitive to nutritional treatments.On the standardized Pacific background deficiencies of cholesterol cause an increase, whereas deficiencies of RNA or thiamine cause a decrease in the expressvity of all four eyeless alleles, but non-identity of their interaction profiles over an array of different suboptimal environments suggest that they may form a group of heteroalleles.


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