scholarly journals AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

Aggregate ◽  
2021 ◽  
Author(s):  
Sanaz Naghibi ◽  
Tong Chen ◽  
Amin Jamshidi Ghahfarokhi ◽  
Youhong Tang
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Protein Imaging

scholarly journals Back Cover: AIEgen‐enhanced protein imaging: Probe design and sensing mechanisms

Aggregate ◽  
2021 ◽  
Vol 2 (3) ◽  
Author(s):  
Sanaz Naghibi ◽  
Tong Chen ◽  
Amin Jamshidi Ghahfarokhi ◽  
Youhong Tang
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Back Cover ◽  
Protein Imaging

scholarly journals Techniques for Molecular Imaging Probe Design

2011 ◽  
Vol 10 (6) ◽  
pp. 7290.2011.00003 ◽  
Author(s):  
Fred Reynolds ◽  
Kimberly A. Kelly
Keyword(s):  
Molecular Imaging ◽  
Target Selection ◽  
Relevant Information ◽  
Probe Design ◽  
Imaging Probe ◽  
Molecular Imaging Probes ◽  
Genomics And Proteomics ◽  
Imaging Probes ◽  
Molecular Imaging Probe ◽  
Underlying Mechanisms

Molecular imaging allows clinicians to visualize disease-specific molecules, thereby providing relevant information in the diagnosis and treatment of patients. With advances in genomics and proteomics and underlying mechanisms of disease pathology, the number of targets identified has significantly outpaced the number of developed molecular imaging probes. There has been a concerted effort to bridge this gap with multidisciplinary efforts in chemistry, proteomics, physics, material science, and biology—all essential to progress in molecular imaging probe development. In this review, we discuss target selection, screening techniques, and probe optimization with the aim of developing clinically relevant molecularly targeted imaging agents.

An Integrated Imaging Probe Design: The Synthesis of99mTc/Re-Containing Macrocyclic Peptide Scaffolds

2014 ◽  
Vol 21 (2) ◽  
pp. 568-578 ◽  
Author(s):  
Jennifer L. Hickey ◽  
Emily J. Simpson ◽  
Jinqiang Hou ◽  
Leonard G. Luyt
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Peptide Scaffolds ◽  
Macrocyclic Peptide

Frontispiece: An Integrated Imaging Probe Design: The Synthesis of99mTc/Re-Containing Macrocyclic Peptide Scaffolds

2015 ◽  
Vol 21 (2) ◽  
pp. n/a-n/a
Author(s):  
Jennifer L. Hickey ◽  
Emily J. Simpson ◽  
Jinqiang Hou ◽  
Leonard G. Luyt
Keyword(s):  
Probe Design ◽  
Imaging Probe ◽  
Peptide Scaffolds ◽  
Macrocyclic Peptide

scholarly journals Metallic nanoparticles as synthetic building blocks for cancer diagnostics: from materials design to molecular imaging applications

2015 ◽  
Vol 3 (28) ◽  
pp. 5657-5672 ◽  
Author(s):  
Vincenzo Mirabello ◽  
David G. Calatayud ◽  
Rory L. Arrowsmith ◽  
Haobo Ge ◽  
Sofia I. Pascu
Keyword(s):  
Molecular Imaging ◽  
Medical Diagnosis ◽  
Metallic Nanoparticles ◽  
Building Blocks ◽  
Cancer Diagnostics ◽  
Probe Design ◽  
Degenerative Diseases ◽  
Imaging Probe ◽  
Molecular Imaging Probe ◽  
Synthetic Scaffolds

New perspectives on the efficiency of metallic nanoparticles as synthetic scaffolds for molecular imaging probe design and their use in medical diagnosis of degenerative diseases such as cancer.

Effects of a Supplemental Spanish Phonological Awareness Intervention on Latinx Preschoolers' Dual Language Emergent Literacy Skills

2020 ◽  
Vol 29 (3) ◽  
pp. 1283-1300
Author(s):  
Xigrid T. Soto ◽  
Andres Crucet-Choi ◽  
Howard Goldstein
Keyword(s):  
At Risk ◽  
Phonological Awareness ◽  
Emergent Literacy ◽  
Language Learners ◽  
Literacy Instruction ◽  
Dual Language ◽  
Literacy Skills ◽  
Dual Language Learners ◽  
Probe Design ◽  
Emergent Literacy Skills

Purpose Preschoolers' phonological awareness (PA) and alphabet knowledge (AK) skills are two of the strongest predictors of future reading. Despite evidence that providing at-risk preschoolers with timely emergent literacy interventions can prevent academic difficulties, there is a scarcity of research focusing on Latinx preschoolers who are dual language learners. Despite evidence of benefits of providing Latinxs with Spanish emergent literacy instruction, few studies include preschoolers. This study examined the effects of a supplemental Spanish PA and AK intervention on the dual emergent literacy skills of at-risk Latinx preschoolers. Method A multiple probe design across four units of instruction evaluated the effects of a Spanish supplemental emergent literacy intervention that explicitly facilitated generalizations to English. Four Latinx preschoolers with limited emergent literacy skills in Spanish and English participated in this study. Bilingual researchers delivered scripted lessons targeting PA and AK skills in individual or small groups for 12–17 weeks. Results Children made large gains as each PA skill was introduced into intervention and generalized the PA skills they learned from Spanish to English. They also improved their English initial sound identification skills, a phonemic awareness task, when instruction was delivered in Spanish but with English words. Children made small to moderate gains in their Spanish letter naming and letter–sound correspondence skills and in generalizing this knowledge to English. Conclusion These findings provide preliminary evidence Latinx preschoolers who are dual language learners benefit from emergent literacy instruction that promotes their bilingual and biliterate development.

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