scholarly journals “Graft Recipient Weight Ratio” or “Graft Volume Standard Liver Volume Ratio” in clinical practice in living donor liver transplantation

2021 ◽  
Author(s):  
Koichiro Haruki ◽  
Kenei Furukawa ◽  
Shinji Onda ◽  
Yoshihiro Shirai ◽  
Toru Ikegami
Keyword(s):  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Weight Ratio ◽  
Volume Ratio ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Standard Liver Volume ◽  
Graft Recipient ◽  
Graft Volume

A new formula for calculating standard liver volume for living donor liver transplantation without using body weight

2015 ◽  
Vol 63 (4) ◽  
pp. 848-854 ◽  
Author(s):  
Takashi Kokudo ◽  
Kiyoshi Hasegawa ◽  
Emilie Uldry ◽  
Yutaka Matsuyama ◽  
Junichi Kaneko ◽  
...  
Keyword(s):  
Liver Transplantation ◽  
Body Weight ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Liver Volume ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Standard Liver Volume ◽  
New Formula

scholarly journals Portal flow modulation in living donor liver transplantation: review with a focus on splenectomy

Surgery Today ◽  
2019 ◽  
Vol 50 (1) ◽  
pp. 21-29 ◽  
Author(s):  
Tomoharu Yoshizumi ◽  
Masaki Mori
Keyword(s):  
Liver Transplantation ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Current Knowledge ◽  
Liver Volume ◽  
Weight Ratio ◽  
Portal Flow ◽  
Donor Liver ◽  
Flow Modulation ◽  
Donor Liver Transplantation

Abstract Small-for-size graft (SFSG) syndrome after living donor liver transplantation (LDLT) is the dysfunction of a small graft, characterized by coagulopathy, cholestasis, ascites, and encephalopathy. It is a serious complication of LDLT and usually triggered by excessive portal flow transmitted to the allograft in the postperfusion setting, resulting in sinusoidal congestion and hemorrhage. Portal overflow injures the liver directly through nutrient excess, endothelial activation, and sinusoidal shear stress, and indirectly through arterial vasoconstriction. These conditions may be attenuated with portal flow modulation. Attempts have been made to control excessive portal flow to the SFSG, including simultaneous splenectomy, splenic artery ligation, hemi-portocaval shunt, and pharmacological manipulation, with positive outcomes. Currently, a donor liver is considered a SFSG when the graft-to-recipient weight ratio is less than 0.8 or the ratio of the graft volume to the standard liver volume is less than 40%. A strategy for transplanting SFSG safely into recipients and avoiding extensive surgery in the living donor could effectively address the donor shortage. We review the literature and assess our current knowledge of and strategies for portal flow modulation in LDLT.

scholarly journals PREOPERATIVE COMPUTED TOMOGRAPHY VOLUMETRY AND GRAFT WEIGHT ESTIMATION IN ADULT LIVING DONOR LIVER TRANSPLANTATION

2017 ◽  
Vol 30 (1) ◽  
pp. 38-41 ◽  
Author(s):  
Rafael S. PINHEIRO ◽  
Ruy J. CRUZ-JR ◽  
Wellington ANDRAUS ◽  
Liliana DUCATTI ◽  
Rodrigo B. MARTINO ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Living Donor ◽  
Living Donor Liver Transplantation ◽  
Normal Liver ◽  
Liver Parenchyma ◽  
Donor Liver ◽  
Donor Liver Transplantation ◽  
Graft Weight ◽  
Computed Tomography Volumetry ◽  
Graft Volume

ABSTRACT Background: Computed tomography volumetry (CTV) is a useful tool for predicting graft weights (GW) for living donor liver transplantation (LDLT). Few studies have examined the correlation between CTV and GW in normal liver parenchyma. Aim: To analyze the correlation between CTV and GW in an adult LDLT population and provide a systematic review of the existing mathematical models to calculate partial liver graft weight. Methods: Between January 2009 and January 2013, 28 consecutive donors undergoing right hepatectomy for LDLT were retrospectively reviewed. All grafts were perfused with HTK solution. Estimated graft volume was estimated by CTV and these values were compared to the actual graft weight, which was measured after liver harvesting and perfusion. Results: Median actual GW was 782.5 g, averaged 791.43±136 g and ranged from 520-1185 g. Median estimated graft volume was 927.5 ml, averaged 944.86±200.74 ml and ranged from 600-1477 ml. Linear regression of estimated graft volume and actual GW was significantly linear (GW=0.82 estimated graft volume, r2=0.98, slope=0.47, standard deviation of 0.024 and p<0.0001). Spearman Linear correlation was 0.65 with 95% CI of 0.45 - 0.99 (p<0.0001). Conclusion: The one-to-one rule did not applied in patients with normal liver parenchyma. A better estimation of graft weight could be reached by multiplying estimated graft volume by 0.82.

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