scholarly journals A Nanostrategy for Efficient Imaging‐Guided Antitumor Therapy through a Stimuli‐Responsive Branched Polymeric Prodrug

2020 ◽  
Vol 7 (6) ◽  
pp. 1903243 ◽  
Author(s):  
Hao Cai ◽  
Xinghang Dai ◽  
Xiaoming Wang ◽  
Ping Tan ◽  
Lei Gu ◽  
...  
2019 ◽  
Vol 37 (1) ◽  
Author(s):  
Zhiqiang Zhang ◽  
Miao Yu ◽  
Tong An ◽  
Jun Yang ◽  
Meijuan Zou ◽  
...  

2019 ◽  
Vol 19 (12) ◽  
pp. 1900329 ◽  
Author(s):  
Yue Wang ◽  
Na Shen ◽  
Kazuo Sakurai ◽  
Zhaohui Tang

Author(s):  
JunJie Tang ◽  
Xiaoge Zhang ◽  
Lili Cheng ◽  
Yadong Liu ◽  
You Chen ◽  
...  

2018 ◽  
Vol 182 ◽  
pp. 235-244 ◽  
Author(s):  
Shuang Bai ◽  
Yong-E Gao ◽  
Xiaoqian Ma ◽  
Xiaoxiao Shi ◽  
Meili Hou ◽  
...  

2021 ◽  
Vol 11 (20) ◽  
pp. 9541
Author(s):  
Zhichu Xiang ◽  
Mouquan Liu ◽  
Jun Song

Biocompatible nanosystems based on polymeric materials are promising drug delivery nanocarrier candidates for antitumor therapy. However, the efficacy is unsatisfying due to nonspecific accumulation and drug release of the nanoparticles in normal tissue. Recently, the nanosystems that can be triggered by tumor-specific stimuli have drawn great interest for drug delivery applications due to their controllable drug release properties. In this review, various polymers and external stimuli that can be employed to develop stimuli-responsive polymeric nanosystems are discussed, and finally, we delineate the challenges in designing this kind of Nanomedicine to improve the therapeutic efficacy.


2020 ◽  
Vol 582 ◽  
pp. 119330 ◽  
Author(s):  
Kishwor Poudel ◽  
Milan Gautam ◽  
Srijan Maharjan ◽  
Jee-Heon Jeong ◽  
Han-Gon Choi ◽  
...  

Pharmaceutics ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 630 ◽  
Author(s):  
Son H. Pham ◽  
Yonghyun Choi ◽  
Jonghoon Choi

The new era of nanotechnology has produced advanced nanomaterials applicable to various fields of medicine, including diagnostic bio-imaging, chemotherapy, targeted drug delivery, and biosensors. Various materials are formed into nanoparticles, such as gold nanomaterials, carbon quantum dots, and liposomes. The nanomaterials have been functionalized and widely used because they are biocompatible and easy to design and prepare. This review mainly focuses on nanomaterials responsive to the external stimuli used in drug-delivery systems. To overcome the drawbacks of conventional therapeutics to a tumor, the dual- and multi-responsive behaviors of nanoparticles have been harnessed to improve efficiency from a drug delivery point of view. Issues and future research related to these nanomaterial-based stimuli sensitivities and the scope of stimuli-responsive systems for nanomedicine applications are discussed.


2019 ◽  
Vol 5 (9) ◽  
pp. 4474-4484 ◽  
Author(s):  
Xuwu Zhang ◽  
Tian Yin ◽  
Shuai Wang ◽  
Zining Hao ◽  
Yaqian He ◽  
...  

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